Researcher
Lily Karamanou
- Disciplines:Microbiology, Systems biology, Laboratory medicine
Affiliations
- Laboratory of Clinical and Epidemiological Virology (Rega Institute) (Division)
Member
From1 Aug 2013 → Today
Projects
11 - 18 of 18
- reconstitution of protein secretion through the Type 3 system.From1 Jan 2016 → 31 Dec 2020Funding: International Cooperation and Mobility
- A "stepping-stone mechanism" for preprotein secretion through the Sec translocaseFrom13 Oct 2015 → 31 Oct 2016Funding: Own budget, for example: patrimony, inscription fees, gifts
- Assembly and substrate switching of the T3S protein export apparatus in enteropathogenic E. coliFrom31 Aug 2015 → 9 Sep 2019Funding: Own budget, for example: patrimony, inscription fees, gifts
- The 3D non-native code of secretory protein sorting and targeting (NONACO3D)From1 Aug 2015 → 2 Apr 2020Funding: FWO Strategic Basic Research Grant
- TOWARDS UNDERSTANDING THE FUNDAMENTAL ASPECTS OF SECRETION MECHANISMS IN E. COLI (Cytoplasmome/secretome divide in E. coli and in vitro reconstitution of the Type 3 Secretion in EPEC)From1 Aug 2015 → 24 Sep 2019Funding: Own budget, for example: patrimony, inscription fees, gifts
- Conformational dynamics of the Sec secretion systemFrom20 Feb 2015 → 29 Nov 2017Funding: Own budget, for example: patrimony, inscription fees, gifts
- Development of proteomics workflows and study of the mechanism for secretion through T3SS in Enteropathogenic E.coli (EPEC)From19 Feb 2015 → 24 Nov 2017Funding: Own budget, for example: patrimony, inscription fees, gifts
- Development and application of broadly applicable microscopy methods and probes for diffraction-unlimited fluctuation imaging of dynamic biological systems.From1 Jan 2015 → 31 Dec 2018Funding: FWO research project (including WEAVE projects)
Publications
1 - 10 of 50
- Enhanced protein secretion in reduced genome strains of Streptomyces lividans(2024)
Authors: Sebastien Carpentier, Kristel Bernaerts, Lily Karamanou
- EndophilinA-dependent coupling between activity-induced calcium influx and synaptic autophagy is disrupted by a Parkinson-risk mutation(2023)
Authors: Marianna Decet, Lily Karamanou, Nikolaos Louros, Tassos Economou, Frederic Rousseau, Joost Schymkowitz, Patrik Verstreken
Pages: 1402 - + - Evolutionary adaptation of the protein folding pathway for secretability(2022)
Authors: Dries Smets, Jochem Smit, Athina Portaliou, Lily Karamanou, Tassos Economou
- Signal Peptide-rheostat Dynamics Delay Secretory Preprotein Folding(2022)
Authors: Dries Smets, Jochem Smit, Ying Xu, Lily Karamanou, Tassos Economou
- Structural dynamics of the non-folded, translocation-competent secretome(2022)
Authors: Dries Smets, Tassos Economou, Lily Karamanou
- Bcl-xL acts as an inhibitor of IP3R channels, thereby antagonizing Ca2+-driven apoptosis(2022)
Authors: Nicolas Rosa, Rita La Rovere, Nikolaos Louros, Lily Karamanou, Frederic Rousseau, Joost Schymkowitz, Tassos Economou, Jan Parys, Geert Bultynck
Pages: 788 - 805 - Preproteins couple the intrinsic dynamics of SecA to its ATPase cycle to translocate via a catch and release mechanism(2022)
Authors: Jochem Smit, Athina Portaliou, Lily Karamanou, Tassos Economou
- Allosteric cross-talk between the hydrophobic cleft and the BH4 domain of Bcl-2 in control of inositol 1,4,5-trisphosphate receptor activity.(2022)
Authors: Lily Karamanou, Tassos Economou, Geert Bultynck
Pages: 375 - 391 - Structural dynamics in the evolution of a bilobed protein scaffold(2021)
Authors: Lily Karamanou, Tassos Economou
- Structural Dynamics of the Functional Nonameric Type III Translocase Export Gate(2021)
Authors: Athina Portaliou, Jochem Smit, Lily Karamanou, Tassos Economou