Researcher
Lily Karamanou
- Disciplines:Microbiology, Systems biology, Laboratory medicine
Affiliations
- Laboratory of Clinical and Epidemiological Virology (Rega Institute) (Division)
Member
From1 Aug 2013 → Today
Projects
1 - 10 of 13
- Bcl-2/IP3R channel structural dynamics underlying complex formation, function and disease (BInamics)From1 Jan 2022 → TodayFunding: FWO research project
- Long-term observation and correlation of protein dynamics using combined single-molecule measurementsFrom1 Jan 2022 → TodayFunding: FWO research project
- Non-folding/folding of the secretome at the single molecule level (SMolFold)From22 Jun 2021 → TodayFunding: BOF - postdoctoral mandates
- Protein folding oscillations in the secretomeFrom1 Oct 2018 → TodayFunding: BOF - Concerted Research Project from 1994, IOF - Industrial Research Fund
- Structural dynamics of the non-folded, translocation-competent secretomeFrom1 May 2018 → 1 May 2022Funding: Own budget, for example: patrimony, inscription fees, gifts
- reconstitution of protein secretion through the Type 3 system.From1 Jan 2016 → 31 Dec 2020Funding: Other resources managed by FWO
- A "stepping-stone mechanism" for preprotein secretion through the Sec translocaseFrom13 Oct 2015 → 31 Oct 2016Funding: Own budget, for example: patrimony, inscription fees, gifts
- Assembly and substrate switching of the T3S protein export apparatus in enteropathogenic E. coliFrom31 Aug 2015 → 9 Sep 2019Funding: Own budget, for example: patrimony, inscription fees, gifts
- The 3D non-native code of secretory protein sorting and targeting (NONACO3D)From1 Aug 2015 → 2 Apr 2020Funding: FWO Strategic Basic Research Grant
- TOWARDS UNDERSTANDING THE FUNDAMENTAL ASPECTS OF SECRETION MECHANISMS IN E. COLI (Cytoplasmome/secretome divide in E. coli and in vitro reconstitution of the Type 3 Secretion in EPEC)From1 Aug 2015 → 24 Sep 2019Funding: Own budget, for example: patrimony, inscription fees, gifts
Publications
1 - 10 of 43
- Preproteins couple the intrinsic dynamics of SecA to its ATPase cycle to translocate via a catch and release mechanism(2022)
Authors: Jochem Smit, Spyridoula Karamanou, Anastassios Economou
Number of pages: 22 - Structural dynamics in the evolution of a bilobed protein scaffold.(2021)
Authors: Spyridoula Karamanou, Anastassios Economou
Pages: e202616511 - Bcl-xL acts as an inhibitor of IP3R channels, thereby antagonizing Ca2+-driven apoptosis(2021)
Authors: Nicolas Rosa, Nikolaos Louros, Spyridoula Karamanou, Frederic Rousseau, Joost Schymkowitz, Anastassios Economou, Jean-Baptiste Parys, Geert Bultynck
Pages: 788 - 805Number of pages: 18 - Probing Universal Protein Dynamics Using Hydrogen-Deuterium Exchange Mass Spectrometry-Derived Residue-Level Gibbs Free Energy(2021)
Authors: Jochem Smit, Srinath Krishnamurthy, Spyridoula Karamanou, Anastassios Economou
Pages: 12840 - 12847Number of pages: 8 - Structural Dynamics of the Functional Nonameric Type III Translocase Export Gate(2021)
Authors: Athina Portaliou, Jochem Smit, Spyridoula Karamanou, Anastassios Economou
Number of pages: 24 - A nexus of intrinsic dynamics underlies translocase priming(2021)
Authors: Srinath Krishnamurthy, Jochem Smit, Spyridoula Karamanou, Anastassios Economou
Pages: 846 - +Number of pages: 20 - Effective Small Molecule Antibacterials from a Novel Anti-Protein Secretion Screen(2021)
Authors: Mohamed Belal Hamed Soliman, Jozef Anné, Spyridoula Karamanou, Anastassios Economou
Number of pages: 17 - A Reporter System for Fast Quantitative Monitoring of Type 3 Protein Secretion in Enteropathogenic E. coli(2020)
Authors: Athina Portaliou, Spyridoula Karamanou, Anastassios Economou
Number of pages: 14 - BDA-366, a putative Bcl-2 BH4 domain antagonist, induces apoptosis independently of Bcl-2 in a variety of cancer cell models(2020)
Authors: Spyridoula Karamanou, Rita La Rovere, Flore Sneyers, Anastassios Economou, Geert Bultynck
Number of pages: 18 - Trigger factor is a bona fide secretory pathway chaperone that interacts with SecB and the translocase(2020)
Authors: Athina Portaliou, Bindu Srinivasu, Srinath Krishnamurthy, Anastassios Economou, Spyridoula Karamanou
Number of pages: 17