Researcher
Lies De Groef
- Disciplines:Animal cell and molecular biology, Animal morphology, anatomy and physiology, Animal pathology, Cell death and senescence, Cell signalling, Neurological and neuromuscular diseases, Neurophysiology, Ophthalmology
Affiliations
- Animal Physiology and Neurobiology (Division)
Member
From1 Jun 2012 → Today
Projects
1 - 10 of 28
- Building towards a patent - Exploitation of the killifish R&D platform to combat neurodegenerative diseasesFrom1 Feb 2024 → TodayFunding: IOF - mandates
- In vivo evaluation of the expression kinetics and immunogenicity of lipid nanoparticle mediated messenger RNA and self-amplifying messenger RNA delivery to the retina.From1 Jul 2023 → TodayFunding: Other federal public and semi-governmental institutions
- Neuron-glia biology in neurodegeneration.From1 Oct 2022 → TodayFunding: BOF - ZAP BOF mandates
- Hyperspectral retinal imaging as a novel biomarker for Alzheimer’s disease: towards a better understanding of the underlying pathological changesFrom26 Sep 2022 → TodayFunding: FWO Strategic Basic Research Grant
- Imaging the invisible in preclinical models using magnetic particle imagingFrom1 May 2022 → TodayFunding: FWO Large scale research infrastructure
- 3D SUper-Resolution to cryo-Electron MIcroscopy to study nanoscale subcellular dynamics and structure that alter in Neurodegenerative Diseases - 3SURE MINDFrom1 May 2022 → TodayFunding: FWO Large scale research infrastructure
- Hyperspectral retinal imaging as a novel diagnostic biomarker for Alzheimer's disease.From1 Jan 2022 → TodayFunding: Private funding of national origin - undefined
- The eye as a window to the brain: tackling neurodegenerative disordersFrom1 Nov 2021 → 31 Oct 2023Funding: Own budget, for example: patrimony, inscription fees, gifts
- The role of extracellular vesicle-microRNAs in Parkinson’s disease: from critical insights into their role in neuroinflammation towards novel microRNA-based therapiesFrom6 Oct 2021 → TodayFunding: FWO Strategic Basic Research Grant, BOF - doctoral mandates
- A killifish R&D platform for therapies improving healthy brain agingFrom1 Oct 2021 → 30 Sep 2023Funding: IOF - technology validation in lab
Publications
41 - 50 of 81
- Target-Derived Neurotrophic Factor Deprivation Puts Retinal Ganglion Cells on Death Row: Cold Hard Evidence and Caveats(2019)
Authors: Marie Claes, Lies De Groef, Lieve Moons
- Non-viral delivery of chemically modified mRNA to the retina: Subretinal versus intravitreal administration(2019)
Authors: Lies De Groef, Lieve Moons
Pages: 315 - 330 - Differential distribution of peroxisomal proteins points to specific roles of peroxisomes in the murine retina(2019)
Authors: Lies De Groef, Marc Fransen, Lieve Moons, Paul P Van Veldhoven, Myriam Baes
Pages: 53 - 62 - The impact of matrix metalloproteinase-3 on neuroinflammation at the blood-retinal barrier: friend or foe?(2019)
Authors: Evy Lefevere, Lieve Moons, Ingeborg Stalmans, Lies De Groef
- Retinal alpha-synuclein deposits in Parkinson’s disease patients and animal models(2019)
Authors: Lien Veys, Marjan Vandenabeele, Veerle Baekelandt, Lieve Moons, Lies De Groef
Pages: 379 - 395 - Extensive growth is followed by neurodegenerative pathology in the continuously expanding adult zebrafish retina(2019)
Authors: Jessie Van houcke, Emiel Geeraerts, Sophie Vanhunsel, An Beckers, Ilse Bollaerts, Lies De Groef, Lieve Moons
Pages: 109 - 125 - Optogenetic stimulation of the superior colliculus confers retinal neuroprotection in a mouse glaucoma model(2019)
Authors: Emiel Geeraerts, Marie Claes, Manuel Salinas Navarro, Lies De Groef, Chris Van den Haute, Isabelle Scheyltjens, Veerle Baekelandt, Lut Arckens, Lieve Moons
Pages: 2313 - 2325 - Prior Exposure to Immunosuppressors Sensitizes Retinal Microglia and Accelerates Optic Nerve Regeneration in Zebrafish(2019)
Authors: Ilse Bollaerts, Jessie Van houcke, An Beckers, Kim Lemmens, Sophie Vanhunsel, Lies De Groef, Lieve Moons
- Oculo-visual abnormalities in Parkinson's disease: possible value as biomarkers.(2018)
Authors: Li Guo, Eduardo Maria Normando, Parth Shah, Lies De Groef, Maria Francesca Cordeiro
Pages: 1390 - 1390 - Oculo-visual abnormalities in Parkinson's disease: possible value as biomarkers.(2018)
Authors: Lies De Groef
Pages: 1390 - 1406