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Researcher
Lies De Groef
- Disciplines:Animal cell and molecular biology, Animal morphology, anatomy and physiology, Animal pathology, Cell death and senescence, Cell signalling, Neurological and neuromuscular diseases, Neurophysiology, Ophthalmology
Affiliations
- Animal Physiology and Neurobiology (Division)
Member
From1 Jun 2012 → Today
Projects
1 - 10 of 28
- Building towards a patent - Exploitation of the killifish R&D platform to combat neurodegenerative diseasesFrom1 Feb 2024 → TodayFunding: IOF - mandates
- In vivo evaluation of the expression kinetics and immunogenicity of lipid nanoparticle mediated messenger RNA and self-amplifying messenger RNA delivery to the retina.From1 Jul 2023 → TodayFunding: Other federal public and semi-governmental institutions
- Neuron-glia biology in neurodegeneration.From1 Oct 2022 → TodayFunding: BOF - ZAP BOF mandates
- Hyperspectral retinal imaging as a novel biomarker for Alzheimer’s disease: towards a better understanding of the underlying pathological changesFrom26 Sep 2022 → TodayFunding: FWO Strategic Basic Research Grant
- Imaging the invisible in preclinical models using magnetic particle imagingFrom1 May 2022 → TodayFunding: FWO Large scale research infrastructure
- 3D SUper-Resolution to cryo-Electron MIcroscopy to study nanoscale subcellular dynamics and structure that alter in Neurodegenerative Diseases - 3SURE MINDFrom1 May 2022 → TodayFunding: FWO Large scale research infrastructure
- Hyperspectral retinal imaging as a novel diagnostic biomarker for Alzheimer's disease.From1 Jan 2022 → TodayFunding: Private funding of national origin - undefined
- The eye as a window to the brain: tackling neurodegenerative disordersFrom1 Nov 2021 → 31 Oct 2023Funding: Own budget, for example: patrimony, inscription fees, gifts
- The role of extracellular vesicle-microRNAs in Parkinson’s disease: from critical insights into their role in neuroinflammation towards novel microRNA-based therapiesFrom6 Oct 2021 → TodayFunding: FWO Strategic Basic Research Grant, BOF - doctoral mandates
- A killifish R&D platform for therapies improving healthy brain agingFrom1 Oct 2021 → 30 Sep 2023Funding: IOF - technology validation in lab
Publications
11 - 20 of 81
- Chronic Chemogenetic Activation of the Superior Colliculus in Glaucomatous Mice: Local and Retrograde Molecular Signature(2022)
Authors: Marie Claes, Stéphane Plaisance, Chris Van den Haute, Lies De Groef, Lut Arckens, Lieve Moons
- The DREADDful Hurdles and Opportunities of the Chronic Chemogenetic Toolbox(2022)
Authors: Marie Claes, Lies De Groef, Lieve Moons
- Retinal imaging biomarkers of neurodegenerative diseases(2022)
Authors: Eirini Christinaki, Hana Kulenovic, Jan Van Eijgen, Lies De Groef, Ingeborg Stalmans
Pages: 194 - 204 - Multimodal retinal imaging to detect and understand Alzheimer’s and Parkinson’s disease(2022)
Authors: Lieve Moons, Lies De Groef
Pages: 1 - 7 - The age factor in optic nerve regeneration: intrinsic and extrinsic barriers hinder successful recovery in the short-living killifish(2022)
Authors: Sophie Vanhunsel, Steven Bergmans, An Beckers, Lies De Groef, Lieve Moons
- Multimodale beeldvorming van het netvlies: een alternatieve blik op vroege diagnose van de ziekte van Alzheimer(2021)
Authors: Sophie Lemmens, Lieve Moons, Ingeborg Stalmans, Lies De Groef
Pages: 41 - 46 - The eye as a window to the brain: Retinal phenotyping of Parkinson’s disease mouse models(2021)
Authors: Lien Veys, Lies De Groef, Lieve Moons
- Early Intervention and Lifelong Treatment with GLP1 Receptor Agonist Liraglutide in a Wolfram Syndrome Rat Model with an Emphasis on Visual Neurodegeneration, Sensorineural Hearing Loss and Diabetic Phenotype(2021)
Authors: Lieve Moons, Lies De Groef
- The Expression of RAAS Key Receptors, Agtr2 and Bdkrb1, Is Downregulated at an Early Stage in a Rat Model of Wolfram Syndrome(2021)
Authors: Lieve Moons, Lies De Groef
- Targeting Plasma Kallikrein With a Novel Bicyclic Peptide Inhibitor (THR-149) Reduces Retinal Thickening in a Diabetic Rat Model(2021)
Authors: Lies De Groef, Lieve Moons
Pages: 1 - 13