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Researcher
Lies De Groef
- Disciplines:Animal cell and molecular biology, Animal morphology, anatomy and physiology, Animal pathology, Cell death and senescence, Cell signalling, Neurological and neuromuscular diseases, Neurophysiology, Ophthalmology
Affiliations
- Animal Physiology and Neurobiology (Division)
Member
From1 Jun 2012 → Today
Projects
1 - 10 of 28
- Building towards a patent - Exploitation of the killifish R&D platform to combat neurodegenerative diseasesFrom1 Feb 2024 → TodayFunding: IOF - mandates
- In vivo evaluation of the expression kinetics and immunogenicity of lipid nanoparticle mediated messenger RNA and self-amplifying messenger RNA delivery to the retina.From1 Jul 2023 → TodayFunding: Other federal public and semi-governmental institutions
- Neuron-glia biology in neurodegeneration.From1 Oct 2022 → TodayFunding: BOF - ZAP BOF mandates
- Hyperspectral retinal imaging as a novel biomarker for Alzheimer’s disease: towards a better understanding of the underlying pathological changesFrom26 Sep 2022 → TodayFunding: FWO Strategic Basic Research Grant
- 3D SUper-Resolution to cryo-Electron MIcroscopy to study nanoscale subcellular dynamics and structure that alter in Neurodegenerative Diseases - 3SURE MINDFrom1 May 2022 → TodayFunding: FWO Large scale research infrastructure
- Imaging the invisible in preclinical models using magnetic particle imagingFrom1 May 2022 → TodayFunding: FWO Large scale research infrastructure
- Hyperspectral retinal imaging as a novel diagnostic biomarker for Alzheimer's disease.From1 Jan 2022 → TodayFunding: Private funding of national origin - undefined
- The eye as a window to the brain: tackling neurodegenerative disordersFrom1 Nov 2021 → 31 Oct 2023Funding: Own budget, for example: patrimony, inscription fees, gifts
- The role of extracellular vesicle-microRNAs in Parkinson’s disease: from critical insights into their role in neuroinflammation towards novel microRNA-based therapiesFrom6 Oct 2021 → TodayFunding: FWO Strategic Basic Research Grant, BOF - doctoral mandates
- A killifish R&D platform for therapies improving healthy brain agingFrom1 Oct 2021 → 30 Sep 2023Funding: IOF - technology validation in lab
Publications
1 - 10 of 81
- The spreading and effects of human recombinant alpha-synuclein pre-formed fibrils in the cerebrospinal fluid of mice(2024)
Authors: Joyce Foroozandeh, Cristiano Lucci, Lies De Groef
Pages: ENEURO.002 - ENEU23.202 - Cdk5-dependent rapid formation and stabilization of dendritic spines by corticotropin-releasing factor(2024)
Authors: Lies De Groef, Lieve Moons
- Retina pathology as a target for biomarkers for Alzheimer's disease: Current status, ophthalmopathological background, challenges, and future directions(2024)
Authors: Lies De Groef, Dietmar Thal
Pages: 728 - 740 - Primary retinal tauopathy: A tauopathy with a distinct molecular pattern(2024)
Authors: Grzegorz Walkiewicz, Sophie Lemmens, Lies De Groef, Dietmar Thal
Pages: 330 - 340 - Molecular and Biochemical Analyses of Aging Hallmarks in the Central Nervous System of the Fast-Aging African Turquoise Killifish(2023)
Authors: Steven Bergmans, Caroline Zandecki, Eve Seuntjens, Lies De Groef, Lieve Moons
- A review on neurodegeneration in the fast-ageing killifish, the first animal model to study the natural occurrence of neuronal cell loss(2023)
Authors: Steven Bergmans, Lieve Moons, Lies De Groef
- Immune stimulation recruits a subset of pro-regenerative macrophages to the retina that promotes axonal regrowth of injured neurons(2023)
Authors: Luca Masin, Isabelle Scheyltjens, Steven Bergmans, Lies De Groef, Lieve Moons
- On the other end of the line: extracellular vesicle-mediated communication in glaucoma(2023)
Authors: Cristiano Lucci, Lies De Groef
- Helicobacter pylori-derived outer membrane vesicles contribute to Alzheimer's disease pathogenesis via C3-C3aR signalling(2023)
Authors: Lien Cools, Lies De Groef
- OCT biomarkers of neurodegenerative diseases – reading the tea leaves or seeing the truth?(2023)
Authors: Eirini Christinaki, Lies De Groef, Ingeborg Stalmans
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