Researcher
Lien Spans
- Disciplines:Genetics, Systems biology, Molecular and cell biology
Affiliations
- Laboratory for Cytogenetics and Genome Research (Division)
Member
From1 Jan 2017 → 31 Dec 2017 - Laboratory for Genetics of Malignant Disorders (Division)
Member
From1 Jan 2015 → 31 Dec 2016 - Laboratory of Molecular Endocrinology (Division)
Member
From1 Sep 2009 → 31 Dec 2014
Publications
11 - 20 of 31
- Recurrent MALAT1-GLI1 oncogenic fusion and GLI1 upregulation define a subset of plexiform fibromyxoma(2016)
Authors: Lien Spans, Raf Sciot, Maria Debiec-Rychter
Pages: 335 - 343 - The Effect of F877L and T878A Mutations on Androgen Receptor Response to Enzalutamide(2016)
Authors: Stefan Prekovic, Arnout Voet, Thomas Van den Broeck, Elien Smeets, Lien Spans, Steven Joniau, Frank Claessens, Christine Helsen
Pages: 1702 - 1712 - The effect of F877L and T878A mutations on androgen receptor response to Enzalutamide(2016)
Authors: Stefan Prekovic, Martin E van Royen, Arnout Voet, Bart Geverts, Rene Houtman, Diana Melchers, Kam YJ Zhang, Thomas Van den Broeck, Elien Smeets, Lien Spans, et al.
Pages: 1702 - 1712 - Genomic and epigenomic analysis of high-risk prostate cancer reveals changes in hydroxymethylation and TET1(2016)
Authors: Lien Spans, Thomas Van den Broeck, Elien Smeets, Stefan Prekovic, Bernard Thienpont, Diether Lambrechts, R Jeffrey Karnes, Nicholas Erho, Mohammed Alshalalfa, Elai Davicioni, et al.
Pages: 24326 - 24338 - Genomic and epigenomic analysis of high-risk prostate cancer reveals changes in hydroxymethylation and TET1(2016)
Authors: Lien Spans, Thomas Van den Broeck, Elien Smeets, Stefan Prekovic, Bernard Thienpont, Diether Lambrechts, Christine Helsen, Thomas Gevaert, Lorenzo Tosco, Karin Haustermans, et al.
Pages: 24326 - 24338 - Dynamic Switching of Active Promoter and Enhancer Domains Regulates Tet1 and Tet2 Expression during Cell State Transitions between Pluripotency and Differentiation(2015)
Authors: Michela Bartoccetti, Rita Khoueiry, Lien Spans, Linde De Troyer, Frank Claessens, Kian Koh
Pages: 1026 - 1042 - What Determines the Difference in DNA Binding Between the Androgen and the Glucocorticoid Receptors?(2015)
Authors: Vanessa Dubois, Christine Helsen, Liesbeth Clinckemalie, Lien Spans, Michaël Laurent, Leen Antonio, Thomas Van den Broeck, Stefan Prekovic, Steven Joniau, Dirk Vanderschueren, et al.
Pages: 59 - 72 - Emerging mechanisms of enzalutamide resistance in prostate cancer(2014)
Authors: Frank Claessens, Christine Helsen, Stefan Prekovic, Thomas Van den Broeck, Lien Spans, Hendrik Van Poppel, Steven Joniau
Pages: 712 - 716 - Comparative genomic and transcriptomic analyses of LNCaP and C4-2B prostate cancer cell lines(2014)
Authors: Lien Spans, Christine Helsen, Liesbeth Clinckemalie, Thomas Van den Broeck, Stefan Prekovic, Steven Joniau, Evelyne Lerut, Frank Claessens
- The role of single nucleotide polymorphisms in predicting prostate cancer risk and therapeutic decision making(2014)
Authors: Thomas Van den Broeck, Steven Joniau, Liesbeth Clinckemalie, Christine Helsen, Stefan Prekovic, Lien Spans, Lorenzo Tosco, Hendrik Van Poppel, Frank Claessens