Researcher
Laurens Liesenborghs
- Disciplines:Microbiology, Systems biology, Laboratory medicine
Affiliations
- Laboratory of Virology and Chemotherapy (Rega Institute) (Division)
Member
From1 Mar 2020 → 31 Aug 2023 - Centre for Molecular and Vascular Biology (Division)
Member
From1 Oct 2008 → 29 Feb 2020
Projects
1 - 3 of 3
- Towards a thermostable dual yellow fever/Lassa fever virus vaccine and therapeutic strategies against the Lassa and related mammarenaviruses.From1 Nov 2020 → 31 Oct 2022Funding: FWO junior postdoctoral fellowship
- Mapping the druggable genome/anti-virome of neglected & emerging RNA viruses using a strategy based on multicolor/multiplex high-content imaging, in vitro evolution and chemogenomicsFrom1 Mar 2020 → 28 Feb 2021Funding: BOF - postdoctoral mandates
- Bacterial pathogens modulate thrombin activity to overcome innate defence mechanisms.From1 Oct 2013 → 22 May 2019Funding: FWO fellowships
Publications
31 - 40 of 60
- An affinity-enhanced, broadly neutralizing heavy chain-only antibody protects against SARS-CoV-2 infection in animal models(2021)
Authors: Lana Langendries, Sofie Jacobs, Sebastiaan ter Horst, Laura Seldeslachts, Laurens Liesenborghs, Robbert Boudewijns, Hendrik Jan Thibaut, Kai Dallmeier, Greetje Vande Velde, Birgit Weynand, et al.
- itraconazole for COVID-19: Preclinical studies and a proof-of-concept randomized clinical trial Laurens (vol 66, 103288, 2021)(2021)
Authors: Laurens Liesenborghs, Dirk Jochmans, Ann Belmans, Iwein Gyselinck, Sebastiaan ter Horst, Erwin Dreesen, Tatjana Geukens, Ewout Landeloos, Bert Vandenberk, Lorenz Van der Linden, et al.
- Venous Thromboembolism in Patients Discharged after COVID-19 Hospitalization(2021)
Authors: Christophe Vandenbriele, Jan Gunst, Marc Jacquemin, Natalie Lorent, Laurens Liesenborghs, Kathelijne Peerlinck, Steffen Rex, Pieter Sinonquel, Lorenz Van der Linden, Robin Vos, et al.
Pages: 362 - 371 - Itraconazole for COVID-19: preclinical studies and a proof-of-concept randomized clinical trial(2021)
Authors: Laurens Liesenborghs, Dirk Jochmans, Ann Belmans, Iwein Gyselinck, Laure-Anne Teuwen, Sebastiaan ter Horst, Erwin Dreesen, Tatjana Geukens, Ewout Landeloos, Vincent Geldhof, et al.
- Direct antivirals working against the novel coronavirus: azithromycin (DAWn-AZITHRO), a randomized, multicenter, open-label, adaptive, proof-of-concept clinical trial of new antivirals working against SARS-CoV-2-azithromycin (vol 22, 126, 2021)(2021)
Authors: Iwein Gyselinck, Laurens Liesenborghs, Ewout Landeloos, Ann Belmans, Geert Verbeke, Peter Verhamme, Robin Vos, Wim Janssens
Pages: 0 - 0 - A randomized, multicentre, open-label phase II proof-of-concept trial investigating the clinical efficacy and safety of the addition of convalescent plasma to the standard of care in patients hospitalized with COVID-19: the Donated Antibodies Working against nCoV (DAWn-Plasma) trial(2020)
Authors: Timothy Devos, Tatjana Geukens, Anne Luyten, Piet Maes, Katleen Vandenberghe, Geert Verbeke, Laurens Liesenborghs, Peter Verhamme, Geert Meyfroidt
- A randomized, multicentre, open-label phase II proof-of-concept trial investigating the clinical efficacy and safety of the addition of convalescent plasma to the standard of care in patients hospitalized with COVID-19: the Donated Antibodies Working against nCoV (DAWn-Plasma) trial (vol 21, 981, 2020)(2020)
Authors: Timothy Devos, Tatjana Geukens, Alexander Schauwvlieghe, Kevin K Arien, Cyril Barbezange, Myriam Cleeren, Veerle Compernolle, Nicolas Dauby, Daniel Desmecht, David Grimaldi, et al.
- A randomized, open-label, adaptive, proof-of-concept clinical trial of modulation of host thromboinflammatory response in patients with COVID-19: the DAWn-Antico study(2020)
Authors: Thomas Vanassche, Quentin Van Thillo, Joost Wauters, Jan Gunst, Carine Wouters, Christophe Vandenbriele, Steffen Rex, Laurens Liesenborghs, Alexander Wilmer, Greet Van den Berghe, et al.
- A single-dose live-attenuated YF17D-vectored SARS-CoV-2 vaccine candidate(2020)
Authors: Lorena Sanchez Felipe, Thomas Vercruysse, Sapna Sharma, Ji Ma, Viktor Lemmens, Robbert Boudewijns, Bert Malengier-Devlies, Laurens Liesenborghs, Suzanne Kaptein, Madina Rasulova, et al.
Pages: 320 - 325 - STAT2 signaling restricts viral dissemination but drives severe pneumonia in SARS-CoV-2 infected hamsters(2020)
Authors: Robbert Boudewijns, Hendrik Jan Thibaut, Suzanne Kaptein, Valentijn Vergote, Laura Seldeslachts, Johan Van Weyenbergh, Sapna Sharma, Laurens Liesenborghs, Ji Ma, Sander Jansen, et al.
Pages: 5838 - 5838