Researcher

Laure Sorber

Research Expertise:Dr. Laure Sorber has extensive experience in molecular biomarkers and oncological research. In her PhD, she has focused on designing the optimal workflow for liquid biopsy, consisting of circulating cell-free (tumor) DNA (cfDNA / ctDNA) and RNA (cfRNA / ctRNA) analysis, for use in research and clinical settings. Her expertise in designing, (clinically) validating, performing and/or analyzing molecular analyses (digital droplet PCR, real-time quantitative / reverse transcriptase PCR, spectrophotometric and fluorometric analyses) has enabled her to act as instructor at Masterclasses. Furthermore, she has intensive experience in organizing (multicenter) studies and evaluating / optimizing sample workflows and quality. Currently, she is working on a joint project with Biocartis NV in which they are evaluating the detection of gene-fusions in a pan-cancer setting.

Keywords:PCR, MOLECULAR ANALYSIS, MOLECULAR DIAGNOSTICS, ONCOLOGY, Biomedical sciences (incl. biochemistry)

Disciplines:Biological system engineering, Biomaterials engineering, Biomechanical engineering, Medical biotechnology, Other (bio)medical engineering, Geomatic engineering, Product development, Safety engineering, Other engineering and technology, Anaesthesiology, Bioinformatics and computational biology, Biomechanics, Biophysics, Cardiac and vascular medicine, Dermatology, Diagnostics, Endocrinology and metabolic diseases, Gastro-enterology and hepatology, Gerontology and geriatrics, Gynaecology and obstetrics, Hematology, Immunology, Intensive care and emergency medicine, Laboratory medicine, Medical biochemistry and metabolism, Medical imaging and therapy, Medical systems biology, Microbiology, Molecular and cell biology, Morphological sciences, Neurosciences, Oncology, Ophthalmology and optometry, Orthopaedics, Otorhinolaryngology, Palliative care and end-of-life care, Paediatrics and neonatology, Physiology, Psychiatry and psychotherapy, Regenerative medicine, Respiratory medicine, Surgery, Tropical medicine, Urology and nephrology, Other basic sciences, Other translational sciences, Other medical and health sciences

Research techniques:Designing, validating, performing and/or analyzing molecular analyses: - real-time quantitative / reverse transcriptase PCR - digital droplet PCR - spectrophotometric and fluorometric analyses Processing of blood samples for the evaluation of circulating cell-free (tumor) DNA and RNA (cfDNA / ctDNA / cfRNA / ctRNA) as well as tissue and cytological samples for DNA and RNA analyses. Organizing of (multicenter) studies.

Users of research expertise:Researchers working on moleculair diagnostics and/or targeted therapies in oncology.