Researcher
Laleh Khodaparast
- Disciplines:Applied immunology, Clinical microbiology
Affiliations
- Switch Laboratory (VIB-KU Leuven) (Division)
Member
From1 Nov 2015 → Today - Laboratory of Clinical Microbiology (Division)
Member
From1 May 2012 → 31 Oct 2015
Projects
1 - 2 of 2
- Investigating the mechanism of action of aggregation-inducing antimicrobial Pept-insFrom30 Oct 2017 → 21 Sep 2021Funding: Own budget, for example: patrimony, inscription fees, gifts
- The Possible Role of the Staphylococcus epidermidis LPxTG Surface Protein SesC in Biofilm Formation and its use as a potentional vaccine targetFrom18 Apr 2012 → 18 May 2017Funding: Own budget, for example: patrimony, inscription fees, gifts
Publications
1 - 10 of 23
- Exploiting the aggregation propensity of beta-lactamases to design inhibitors that induce enzyme misfolding(2023)
Authors: Laleh Khodaparast, Ladan Khodaparast, Emiel Michiels, Rodrigo Gallardo, Bert Houben, Frederic Rousseau, Joost Schymkowitz
- Reverse engineering synthetic antiviral amyloids (vol 11, 2832, 2020)(2023)
Authors: Emiel Michiels, Rodrigo Gallardo, Laleh Khodaparast, Ladan Khodaparast, Rob van der Kant, Bert Houben, Nikolaos Louros, Suzanne Kaptein, Guy Bormans, Johan Neyts, et al.
- Sequence-targeted Peptides Divert Functional Bacterial Amyloid Towards Destabilized Aggregates and Reduce Biofilm Formation(2023)
Authors: Nikolaos Louros, Laleh Khodaparast, Ladan Khodaparast, Frederic Rousseau, Joost Schymkowitz
- Enhanced therapeutic window for antimicrobial Pept-ins by investigating their structure-activity relationship(2023)
Authors: Laleh Khodaparast, Ladan Khodaparast, Nikolaos Louros, Rodrigo Gallardo, Frederic Rousseau, Joost Schymkowitz
- Exploiting the intrinsic misfolding propensity of the KRAS oncoprotein(2023)
Authors: Kobe Janssen, Filip Claes, Bert Houben, Mieke Nys, Laleh Khodaparast, Ladan Khodaparast, Nikolaos Louros, Rob van der Kant, Katerina Konstantoulea, Joost Schymkowitz, et al.
- Erratum for Mortier and Gayán et al., "Gene Erosion Can Lead to Gain-of-Function Alleles That Contribute to Bacterial Fitness".(2021)
Authors: Julien Mortier, Elisa Gayán, Ronald Van Eyken, Oscar Enrique Torres Montaguth, Laleh Khodaparast, Ladan Khodaparast, Bert Houben, Sebastien Carpentier, Frederic Rousseau, Joost Schymkowitz, et al.
Pages: e0246721 - Investigating the mechanism of action of aggregation-inducing antimicrobial Pept-ins(2021)
Authors: Guiqin Wu, Joost Schymkowitz, Frederic Rousseau, Laleh Khodaparast, Ladan Khodaparast
- Synthetic Pept-Ins as a Generic Amyloid-Like Aggregation-Based Platform for In Vivo PET Imaging of Intracellular Targets(2021)
Authors: Kaat Luyten, Laleh Khodaparast, Ladan Khodaparast, Filip Claes, Rodrigo Gallardo, Michel Koole, Joost Schymkowitz, Guy Bormans, Frederic Rousseau
Pages: 2052 - 2064 - The Dynamic Transition of Persistence toward the Viable but Nonculturable State during Stationary Phase Is Driven by Protein Aggregation(2021)
Authors: Liselot Dewachter, Celien Bollen, Dorien Wilmaerts, Elen Louwagie, Paul Matthay, Laleh Khodaparast, Ladan Khodaparast, Frederic Rousseau, Joost Schymkowitz, Jan Michiels
- Gene Erosion Can Lead to Gain-of-Function Alleles That Contribute to Bacterial Fitness(2021)
Authors: Julien Mortier, Ronald Van Eyken, Laleh Khodaparast, Ladan Khodaparast, Bert Houben, Sebastien Carpentier, Frederic Rousseau, Joost Schymkowitz, Abram Aertsen
Patents
1 - 1 of 1
- Beta-lactamase inhibitors (Inventor)