Researcher
Koen Van Laere
- Disciplines:Medical imaging and therapy, Medicinal products
Affiliations
- Nuclear Medicine & Molecular Imaging (Division)
Responsible
From1 Oct 2012 → Today - Nuclear Medicine & Molecular Imaging (Division)
Member
From1 Oct 2002 → Today
Infrastructure
1 - 3 of 3
- simultaneous time-of-flight PET-MR scanner (Consortium coordinator)
- Flanders BioImaging: towards an integrated, translational and multimodal imaging platform from molecule to man. (Consortium coordinator)
- FB-III (“FB triple-I”) : Flanders BioImaging: Integrating Imaging Infrastructure from cell to man. (Consortium coordinator)
Projects
1 - 10 of 51
- Prospective clinical diagnostic performance of the novel fibroblast imaging tracer 18F-AlF-FAPI-74 versus standard of care 18F-FDG PET/CT in inflammatory disorders and fever/inflammation of unknown origin.From16 Apr 2024 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Towards mechanistic biomarkers for amyotrophic lateral sclerosisFrom1 Jan 2024 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Prospective head-to-head comparison of cardiac [18F]-MFBG PET versus [123I]-MIBG SPECT in the differentiation between Parkinson’s disease and multiple system atrophy and between dementia with Lewy bodies and Alzheimer’s disease.From1 Oct 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- In vivo PET of synaptic density in cognitive disorders: prospective evaluation of neuronal dysfunction and relation to symptomatology.From1 Oct 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- [18F]-MFBG PET of the cardiac noradrenergic system for early differentiation in Parkinson’s disease and dementia with Lewy bodies.From1 Oct 2023 → TodayFunding: FWO Applied Biomedical Research (TBM)
- Flanders BioImaging: Leading Imaging Application Integrated Service and Enablement (FBI-LIAISE)From1 Jan 2023 → TodayFunding: FWO International research infrastructure (IRI)
- IMAGINATION : IMAGing bIomarkers for diagNosis, therAnosTIcs and drug develOpmeNtFrom1 Oct 2022 → TodayFunding: IOF - mandates
- A multi-modal approach to study C9orf72-mediated diseaseFrom16 May 2022 → 15 May 2023Funding: BOF - postdoctoral mandates
- Innovative concepts for PET-MR imaging of brain function and brain-gut interactionsFrom14 Jan 2022 → TodayFunding: BOF - doctoral mandates
- In vivo PET of synaptic density as potential diagnostic marker for AD and DLB: Prospective comparison with current imaging markers for neuronal dysfunction and relation to symptomatologyFrom1 Jan 2022 → TodayFunding: Private funding of national origin - undefined
Publications
21 - 30 of 452
- Relative glucose metabolic activity per synapse (rMAPS) is regionally varying but preserved in healthy ageing and in Huntington's disease - a dual 18F-FDG and 11C-UCB-J PET/MR study(2023)
Authors: Koen Van Laere, Greet Vanderlinden, Mathieu Vandenbulcke, Georg Schramm
- Longitudinal Synaptic Density PET with 11C-UCB-J 6 Months After Ischemic Stroke(2023)
Authors: Marjan Coremans, Mathieu Vandenbulcke, Geert Verheyden, Michel Koole, Koen Van Laere, Robin Lemmens
Pages: 911 - 921 - Higher diagnostic yield of 18F-FDG PET in inflammation of unknown origin compared to fever of unknown origin(2023)
Authors: Lien Moreel, Daniel Engelbert Blockmans, Koen Van Laere, Steven Vanderschueren
Pages: 71 - 76 - Development, initial validation, and application of a visual read method for [18F]MK-6240 tau PET(2023)
Authors: Koen Van Laere
- Differences in Cerebral Glucose Metabolism in ALS Patients with and without C9orf72 and SOD1 Mutations(2023)
Authors: Joke De Vocht, Fouke Ombelet, Pegah Masrori, Hilde Van Esch, Michel Koole, Patrick Dupont, Koen Van Laere, Philip Van Damme
- [18F] MFBG PET imaging: biodistribution, pharmacokinetics, and comparison with [123I] MIBG in neural crest tumour patients(2023)
Authors: Sofie Celen, Kristof Baete, Michel Koole, Oliver Bechter, Paul Clement, Koen Van Laere, Guy Bormans, Christophe Deroose
Pages: 1134 - 1145 - SDI-118, a Novel Procognitive SV2A Modulator: First-in-Human 1 Randomized Controlled Trial Including PET/fMRI Assessment of 2 Target Engagement(2023)
Authors: Michel Koole, Koen Van Laere, Stefan Sunaert
- In vivo imaging of synaptic density in Parkinson’s and Huntington’s disease.(2023)
Authors: Aline Delva, Wim Vandenberghe, Koen Van Laere
- In Vivo Detection of Neurofibrillary Tangles by 18F-MK-6240 PET/MR in Patients With Ischemic Stroke(2023)
Authors: Stefan Sunaert, Mathieu Vandenbulcke, Guy Bormans, Geert Verheyden, Michel Koole, Koen Van Laere, Robin Lemmens
Pages: E62 - E71 - Multiplex core of the human brain using structural, functional and metabolic connectivity derived from hybrid PET-MR imaging.(2023)
Authors: Koen Van Laere, Michel Koole
Pages: 1115965