Researcher
Kevin Braeckmans
- Keywords:nanomedicines, biophotonics, medical nanotechnology, drug delivery, microscopy
- Disciplines:Nanobiotechnology, Nanoscale characterisation, Nanophotonics, Nanometrology, In vitro testing, Biopharmaceuticals, Non-clinical studies, Nanomaterials, Medical nanotechnology, Biopharmaceutics, Physical pharmacy
Affiliations
- Department of Pharmaceutics (Department)
Member
From1 Aug 1999 → Today
Infrastructure
1 - 4 of 4
- Flanders BioImaging (Consortium partner)
- A multimodal non-linear optical platform for 2l3-photon excitation and 2ndl3rd harmonic imaging deep inside living tissues and animals (Consortium partner)
- Confocal and two-photon Microscope (Consortium coordinator)
- Stimulated Emission Depletion Microscope (Consortium coordinator)
Projects
1 - 10 of 56
- Engineering of universal iPSC-derived therapeutic cells by nanofiber photoporation.From1 Nov 2023 → TodayFunding: FWO Strategic Basic Research Grant
- Analysis and prevention of protein particle formation – An approach towards safer antibody drugs in the clinicFrom1 Nov 2023 → TodayFunding: FWO Strategic Basic Research Grant
- Engineering of universal iPSC-derived therapeutic cells by nanofiber photoporation.From1 Oct 2023 → 31 Oct 2023Funding: BOF - doctoral mandates
- Uncovering the mechanism underlying and consequences of alphaherpesvirus-induced formation of tunneling nanotubes (TNTs)From1 Oct 2023 → TodayFunding: BOF - doctoral mandates
- Flanders BioImaging: Leading Imaging Application Integrated Service and Enablement (FBI-LIAISE)From1 Jan 2023 → TodayFunding: FWO International research infrastructure (IRI)
- Evaluation of cellular dynamics using automated widefield imagingFrom15 Dec 2022 → TodayFunding: BOF - scientific equipment program
- Single-cell ICP-mass spectrometry in the biological sciences: on the way to real-world useFrom1 Nov 2022 → 31 Dec 2022Funding: FWO senior postdoctoral fellowship
- NOn-VIral gene modified STEM cell therapyFrom1 Nov 2022 → TodayFunding: HORIZON.3.1 - European Innovation Council (EIC)
- Selective photoporation of the nuclear envelope to mimic pathological defects and facilitate intranuclear delivery.From1 Oct 2022 → TodayFunding: BOF - mobility
- Cofunding core facility - Ghent Light Microscopy (GLiM)From1 Jul 2022 → TodayFunding: BOF - research organisations
Publications
41 - 50 of 235
- Does the mode of dispersion determine the properties of dispersed Pseudomonas aeruginosa biofilm cells?(2020)
Authors: Jasper Wille, Eline Teirlinck, Andrea Sass, Filip Van Nieuwerburgh, Volkhard Kaever, Kevin Braeckmans
- Vapor nanobubble is the more reliable photothermal mechanism for inducing endosomal escape of siRNA without disturbing cell homeostasis(2020)
Authors: Juan Fraire, Gaëlle Houthaeve, Jing Liu, Laurens Raes, Lotte Vermeulen, Stephan Stremersch, Toon Brans, Gerardo Garcia-Diaz Barriga, Sarah De Keulenaer, Filip Van Nieuwerburgh, et al.
Pages: 262 - 275 - Intracellular labeling with extrinsic probes : delivery strategies and applications(2020)
Authors: Jing Liu, Juan Fraire, Stefaan De Smedt, Ranhua Xiong, Kevin Braeckmans
- Fluorescence-based quantification of messenger RNA and plasmid DNA decay kinetics in extracellular biological fluids and cell extracts(2020)
Authors: Heyang Zhang, Koen Rombouts, Laurens Raes, Ranhua Xiong, Stefaan De Smedt, Kevin Braeckmans, Katrien Remaut
- Nanomaterials to avoid and destroy protein aggregates(2020)
Authors: Félix Sauvage, Joost Schymkowitz, Frederic Rousseau, Bela Z. Schmidt, Katrien Remaut, Kevin Braeckmans
- Intracellular delivery of mRNA in adherent and suspension cells by vapor nanobubble photoporation(2020)
Authors: Laurens Raes, Stephan Stremersch, Juan Fraire, Toon Brans, Glenn Goetgeluk, Stijn De Munter, Lien Van Hoecke, Rein Verbeke, Jelter Van Hoeck, Ranhua Xiong, et al.
- Targeted nanoparticles towards increased L cell stimulation as a strategy to improve oral peptide delivery in incretin-based diabetes treatment(2020)
Authors: Yining Xu, Herlinde De Keersmaecker, Kevin Braeckmans, Stefaan De Smedt, Patrice D. Cani, Véronique Préat, Ana Beloqui
- Long-term live-cell microscopy with labeled nanobodies delivered by laser-induced photoporation(2020)
Authors: Jing Liu, Tim Hebbrecht, Toon Brans, Eef Parthoens, Saskia Lippens, Chengnan Li, Herlinde De Keersmaecker, Winnok H. De Vos, Rabah Boukherroub, Jan Gettemans, et al.
Pages: 485 - 495 - Materials and technologies to combat counterfeiting of pharmaceuticals : current and future problem tackling(2020)
Authors: Heyang Zhang, Dawei Hua, Chaobo Huang, Sangram Keshari Samal, Ranhua Xiong, Félix Sauvage, Kevin Braeckmans, Katrien Remaut, Stefaan De Smedt
- The role of small proteins in Burkholderia cenocepacia J2315 biofilm formation, persistence and intracellular growth(2019)
Authors: Heleen Van Acker, Aurélie Crabbé, Dukas Jurenas, Lisa Ostyn, Andrea Sass, Simon Daled, Maarten Dhaenens, Dieter Deforce, Eline Teirlinck, Herlinde De Keersmaecker, et al.
Patents
1 - 9 of 9
- Composition comprising at least one nanobomb suitable for altering a biological barrier (Inventor)
- Composition for treatment of vitreous disease or disorder (Inventor)
- Method to increase the permeability of the plasma membrane of cells and a structure suitable for use in such method (Inventor)
- Method and device to provide a microfluidic flow (Inventor)
- Method and system for characterizing extracellular vesicles (Inventor)
- Composition comprising at least one nanobomb suitable for altering a biological barrier (Inventor)
- Composition for treatment of vitreous disease or disorder (Inventor)
- Method and system for characterizing extracellular vesicles (Inventor)
- Method and system for dispersion measurements (Inventor)