Researcher
Kevin Braeckmans
- Keywords:nanomedicines, biophotonics, medical nanotechnology, drug delivery, microscopy
- Disciplines:Nanobiotechnology, Nanoscale characterisation, Nanophotonics, Nanometrology, In vitro testing, Biopharmaceuticals, Non-clinical studies, Nanomaterials, Medical nanotechnology, Biopharmaceutics, Physical pharmacy
Affiliations
- Department of Pharmaceutics (Department)
Member
From1 Aug 1999 → Today
Infrastructure
1 - 4 of 4
- Flanders BioImaging (Consortium partner)
- A multimodal non-linear optical platform for 2l3-photon excitation and 2ndl3rd harmonic imaging deep inside living tissues and animals (Consortium partner)
- Confocal and two-photon Microscope (Consortium coordinator)
- Stimulated Emission Depletion Microscope (Consortium coordinator)
Projects
1 - 10 of 56
- Engineering of universal iPSC-derived therapeutic cells by nanofiber photoporation.From1 Nov 2023 → TodayFunding: FWO Strategic Basic Research Grant
- Analysis and prevention of protein particle formation – An approach towards safer antibody drugs in the clinicFrom1 Nov 2023 → TodayFunding: FWO Strategic Basic Research Grant
- Engineering of universal iPSC-derived therapeutic cells by nanofiber photoporation.From1 Oct 2023 → 31 Oct 2023Funding: BOF - doctoral mandates
- Uncovering the mechanism underlying and consequences of alphaherpesvirus-induced formation of tunneling nanotubes (TNTs)From1 Oct 2023 → TodayFunding: BOF - doctoral mandates
- Flanders BioImaging: Leading Imaging Application Integrated Service and Enablement (FBI-LIAISE)From1 Jan 2023 → TodayFunding: FWO International research infrastructure (IRI)
- Evaluation of cellular dynamics using automated widefield imagingFrom15 Dec 2022 → TodayFunding: BOF - scientific equipment program
- Single-cell ICP-mass spectrometry in the biological sciences: on the way to real-world useFrom1 Nov 2022 → 31 Dec 2022Funding: FWO senior postdoctoral fellowship
- NOn-VIral gene modified STEM cell therapyFrom1 Nov 2022 → TodayFunding: HORIZON.3.1 - European Innovation Council (EIC)
- Selective photoporation of the nuclear envelope to mimic pathological defects and facilitate intranuclear delivery.From1 Oct 2022 → TodayFunding: BOF - mobility
- Cofunding core facility - Ghent Light Microscopy (GLiM)From1 Jul 2022 → TodayFunding: BOF - research organisations
Publications
21 - 30 of 235
- ICG-mediated photodisruption of the inner limiting membrane enhances retinal drug delivery(2022)
Authors: Karen Peynshaert, Helena Vanluchene, Kaat De Clerck, An-Katrien Minnaert, Morgane Verhoeven, Noémie Gouspillou, Nezahat Bostan, Toshio Hisatomi, Geraldine Accou, Félix Sauvage, et al.
Pages: 315 - 326 - Physical transfection technologies for macrophages and dendritic cells in immunotherapy(2021)
Authors: Aranit Harizaj, Ine Lentacker, Kevin Braeckmans
Pages: 229 - 247 - Vapor nanobubble-mediated photoporation constitutes a versatile intracellular delivery technology(2021)
Authors: Jana Ramon, Ranhua Xiong, Stefaan De Smedt, Koen Raemdonck, Kevin Braeckmans
- Concentration gradients in material sciences : methods to design and biomedical applications(2021)
Authors: Dawei Hua, Ranhua Xiong, Kevin Braeckmans, Benoit Scheid, Chaobo Huang, Félix Sauvage, Stefaan De Smedt
- Photothermal nanofibres enable safe engineering of therapeutic cells(2021)
Authors: Ranhua Xiong, Dawei Hua, Jelter Van Hoeck, Dominika Berdecka, Laurens Léger, Stijn De Munter, Juan Fraire, Laurens Raes, Aranit Harizaj, Félix Sauvage, et al.
Pages: 1281 - 1291 - Together is better : mRNA co‐encapsulation in lipoplexes is required to obtain ratiometric co‐delivery and protein expression on the single cell level(2021)
Authors: Heyang Zhang, Jeroen Bussmann, Florian H. Huhnke, Joke Devoldere, An-Katrien Minnaert, Wim Jiskoot, Friedhelm Serwane, Joachim Spatz, Magnus Röding, Stefaan De Smedt, et al.
- Cytosolic delivery of gadolinium via photoporation enables improved in vivo magnetic resonance imaging of cancer cells(2021)
Authors: Aranit Harizaj, Benedicte Descamps, Christophe Mangodt, Stephan Stremersch, Arianna Stoppa, Lieve Balcaen, Toon Brans, Nausikaa Devriendt, Juan Fraire, Eduardo Bolea Fernandez, et al.
Pages: 4005 - 4018 - Non-viral transfection technologies for next-generation therapeutic T cell engineering(2021)
Authors: Laurens Raes, Koen Raemdonck, Kevin Braeckmans
- Cas9 RNP transfection by vapor nanobubble photoporation for ex vivo cell engineering(2021)
Authors: Laurens Raes, Aranit Harizaj, Glenn Goetgeluk, Jelter Van Hoeck, Stephan Stremersch, Juan Fraire, Toon Brans, Olivier Gerrit de Jong, Roel Maas-Bakker, Enrico Mastrobattista, et al.
Pages: 696 - 707 - Bubble forming films for spatial selective cell killing(2021)
Authors: Dawei Hua, Aranit Harizaj, Mike Wels, Toon Brans, Stephan Stremersch, Herlinde De Keersmaecker, Eduardo Bolea Fernandez, Dimitri Roels, Kevin Braeckmans, Ranhua Xiong, et al.
Patents
1 - 9 of 9
- Composition comprising at least one nanobomb suitable for altering a biological barrier (Inventor)
- Composition for treatment of vitreous disease or disorder (Inventor)
- Method to increase the permeability of the plasma membrane of cells and a structure suitable for use in such method (Inventor)
- Method and device to provide a microfluidic flow (Inventor)
- Method and system for characterizing extracellular vesicles (Inventor)
- Composition comprising at least one nanobomb suitable for altering a biological barrier (Inventor)
- Composition for treatment of vitreous disease or disorder (Inventor)
- Method and system for characterizing extracellular vesicles (Inventor)
- Method and system for dispersion measurements (Inventor)