Researcher
Katrien Remaut
- Keywords:lipid nanoparticles, mRNA delivery, innate immunity, peritoneal carcinomatosis, non-viral gene delivery, ocular gene therapy
- Disciplines:Nanobiotechnology, Other biological sciences not elsewhere classified, Environmental safety and health of nanotechnology, Nanoscale characterisation, Nanotechnology not elsewhere classified, Nanophotonics, Nanometrology, Drug discovery and development not elsewhere classified, Clinical trials, Compound screening, Other pharmaceutical sciences not elsewhere classified, Biopharmaceuticals, In vitro testing, Non-clinical studies, Vaccines, Nanomaterials, Nanomanufacturing, Nanofabrication, growth and self assembly, Nanoelectromechanical systems
Affiliations
- Department of Pharmaceutics (Department)
Member
From1 Oct 2001 → Today
Infrastructure
1 - 1 of 1
- Confocal and two-photon Microscope (Consortium partner)
Projects
1 - 10 of 29
- ILM photodisruption: a biophotonic approach to promote retinal ganglion cell engraftment as a cure for blindnessFrom1 Nov 2023 → TodayFunding: FWO senior postdoctoral fellowship
- Postdoctoral Fellowship Program in National Glaucoma Research: "“Exploring ICG-mediated ILM photodisruption as a tool to boost retinal ganglion cell engraftment"From1 Jul 2023 → TodayFunding: Foreign private sponsor - undefined
- Let There Be Light: two biophotonic approaches to boost retinal ganglion cell transplantation as a cure for blindnessFrom1 Nov 2022 → TodayFunding: FWO Strategic Basic Research Grant
- Nanoparticle formulations of toll-like receptor agonists and oxaliplatin for local intraperitoneal delivery to treat colorectal peritoneal metastasisFrom1 Nov 2022 → TodayFunding: FWO Strategic Basic Research Grant
- INTRAPERITONEAL IMMUNE MODULATION FOR COLORECTAL PERITONEAL METASTASESFrom1 Nov 2022 → TodayFunding: FWO research project (including WEAVE projects)
- In vivo evaluation of the expression kinetics and immunogenicity of lipid nanoparticle mediated messenger RNA and self-amplifying messenger RNA delivery to the retinaFrom18 Apr 2022 → 17 Apr 2023Funding: Foundations, funds and other with scientific goal
- Toekenning: ARVO Foundation for Eye Research and the Eye Bank Association of America EyeFind Research: "Grant Karen Peynshaert"From1 Feb 2022 → 31 Jan 2023Funding: Foreign Nonprofit organisations and equivalents
- Design of a novel antisense oligonucleotide therapy for inherited blindnessFrom1 Nov 2021 → TodayFunding: FWO Strategic Basic Research Grant
- Intraperitoneal Aerosolized Liposomal Irinotecan (NalIRI) in Peritoneal Carcinomatosis from GI cancer: a phase I firstinhuman studyFrom1 Aug 2021 → TodayFunding: Private funding of national origin - undefined
- Genetic therapy for EYS- and USH2A-associated retinal dystrophy ("GET-READY")From1 Jun 2021 → TodayFunding: FWO research project (including WEAVE projects)
Publications
1 - 10 of 90
- Nucleic acid degradation as barrier to gene delivery : a guide to understand and overcome nuclease activity(2024)
Authors: Heyang Zhang, Jo Vandesompele, Kevin Braeckmans, Stefaan De Smedt, Katrien Remaut
Pages: 317 - 360 - Repositioning the antihistamine ebastine as an intracellular siRNA delivery enhancer(2023)
Authors: Cristina Muntean, Eva Blondeel, Laure Harinck, Kunal Pednekar, Jai Prakash, Olivier De Wever, Jeanne Leblond Chain, Stefaan De Smedt, Katrien Remaut, Koen Raemdonck
- Smart hydrogels delivered by high pressure aerosolization can prevent peritoneal adhesions(2023)
Authors: Helena Braet, Peter-Paul Fransen, Yong Chen, Simon Van Herck, Remco Mariën, Valérie Vanhoorne, Wim Ceelen, Annemieke Madder, Steven Ballet, Richard Hoogenboom, et al.
Pages: 138 - 150 - The effect of electrostatic high pressure nebulization on the stability, activity and ex vivo distribution of ionic self-assembled nanomedicines(2023)
Authors: Helena Braet, Valentina Andretto, Remco Mariën, Beyza Yücesan, Stefan van der Vegte, Ragna Haegebaert, Giovanna Lollo, Stefaan De Smedt, Katrien Remaut
Pages: 318 - 329 - Dual-modality hafnium oxide nanocrystals for in vivo computed tomography and fluorescence imaging of sentinel lymph nodes(2023)
Authors: Loren Deblock, Benedicte Descamps, Ilia Goemaere, Eline Goossens, Glenn Vergauwen, Jens Debacker, Philippe Tummers, Katrien Remaut, Isabel Van Driessche, Klaartje De Buysser, et al.
Pages: 8883 - 8896 - CO2-driven nebulization of pH-sensitive supramolecular polymers for intraperitoneal hydrogel formation and the treatment of peritoneal metastasis(2023)
Authors: Helena Braet, Peter-Paul Fransen, Remco Mariën, Giovanna Lollo, Wim Ceelen, Chris Vervaet, Lieve Balcaen, Frank Vanhaecke, Christian Vanhove, Stefan van der Vegte, et al.
Pages: 49022 - 49034 - Every nano-step counts : a critical reflection on do’s and don’ts in researching nanomedicines for retinal gene therapy(2023)
Authors: Karen Peynshaert, Joke Devoldere, Katrien Remaut
Pages: 259 - 271 - Yeast-produced fructosamine-3-kinase retains mobility after ex vivo intravitreal injection in human and bovine eyes as determined by Fluorescence Correlation Spectroscopy(2022)
Authors: An-Katrien Minnaert, Loes van Schie, Hendrik Grootaert, Jonas Himpe, Simon Devos, Wannes Weyts, Herlinde De Keersmaecker, Kevin Braeckmans, Katrien Remaut
- Laser-induced nanobubbles safely ablate vitreous opacities in vivo(2022)
Authors: Félix Sauvage, Van Phuc Nguyen, Yanxiu Li, Aranit Harizaj, J. Sebag, Dimitri Roels, Viktor Van Havere, Karen Peynshaert, Ranhua Xiong, Juan Fraire, et al.
Pages: 552 - 559 - Nanoparticle mediated targeting of toll-like receptors to treat colorectal cancer(2022)
Authors: Ragna Haegebaert, Maxime Kempers, Wim Ceelen, Ine Lentacker, Katrien Remaut
Pages: 16 - 30
Patents
1 - 2 of 2