Researcher
Katleen De Preter
- Keywords (Ghent University):DNA and RNA sequencing, genomics, bioinformatics, single cell analysis, Computational deconvolution, liquid biopsies, biomarker studies
- Disciplines (Flanders Institute for Biotechnology):Analytical biochemistry, Cell death and senescence, Analysis of next-generation sequence data, General diagnostics
- Disciplines (Ghent University):Genomics, Medical metagenomics, Medical genomics, Medical epigenomics, Cancer diagnosis, Cancer biology, Molecular diagnostics
- See also: Katleen De Preter (Flanders Institute for Biotechnology)
Affiliations
- De Preter Lab (Research group)
Responsible
From25 Oct 2022 → Today - Department of Biomolecular Medicine (Department)
Member
From1 Oct 2018 → Today - Department of Pediatrics and medical genetics (Department)
Member
From1 Oct 2000 → 30 Sep 2018
Projects
1 - 10 of 19
- A SIOPEN pragmatic clinical trial to MOnitor NeuroblastomA relapse with LIquid biopsy Sensitive AnalysisFrom1 Jan 2024 → TodayFunding: HORIZON.2.1 - Health
- Universal, cost-effective and hypersensitive open-source technology platform for liquid biopsy based on methylome profiling of circulating DNA.From1 Jan 2024 → TodayFunding: BOF - projects
- NIPITplus, a multi-cancer blood test to predict immune checkpoint inhibitor response and monitor toxicityFrom1 Jan 2023 → TodayFunding: Foundations, funds and other with scientific goal
- Tracking epigenetic plasticity in circulating tumor-derived DNA to monitor drug resistance and guide personalized treatment in cancer patientsFrom1 Sep 2022 → 31 Dec 2022Funding: HORIZON.1.1 - European Research Council (ERC)
- SpatialConnect: linking tissue biology to the new era of single-cell spatial transcriptomicsFrom1 May 2022 → TodayFunding: FWO Medium Size Research Infrastructure
- Replication fork protector dependency factors: novel targets for combination treatment and immunomodulation in neuroblastoma (REINFORCE)From1 Jan 2022 → TodayFunding: BOF - projects
- The DNA methylome in Common Variable Immunodeficiencies (CVID): a comprehensive study characterizing its heterogeneity and its role in disease subclassificationFrom1 Nov 2021 → TodayFunding: FWO fellowships
- Prediction of immunotherapy response and toxicity in melanoma, renal cell and lung cancer using transcriptome based systemic immune phenotyping.From1 Nov 2021 → TodayFunding: FWO fellowships
- Development of a minimally-invasive test for accurate diagnosis of Cancer of Unknown Primary (CUP) using DNA methylation profilingFrom1 Oct 2021 → TodayFunding: BOF - projects
- Development of a fast, minimally-invasive and affordable test for accurate diagnosis of Cancer of Unknown Primary (CUP) using DNA methylation profiling.From1 Nov 2020 → 31 Oct 2022Funding: FWO Strategic Basic Research Grant
Publications
1 - 10 of 66
- MYCN and SNRPD3 cooperate to maintain a balance of alternative splicing events that drives neuroblastoma progression(2024)
Authors: Alice Salib, Nisitha Jayatilleke, Janith A. Seneviratne, Chelsea Mayoh, Katleen De Preter, Franki Speleman, Belamy B. Cheung, Daniel R. Carter, Glenn M. Marshall
Pages: 363 - 377 - Evaluation of single-sample network inference methods for precision oncology(2024)
Authors: Joke Deschildre, Boris Vandemoortele, Jens Uwe Loers, Katleen De Preter, Vanessa Vermeirssen
- Human iPSC modeling recapitulates in vivo sympathoadrenal development and reveals an aberrant developmental subpopulation in familial neuroblastoma(2024)
Authors: Stéphane Van Haver, Yujie Fan, Sarah-Lee Bekaert, Celine Everaert, Wouter Van Loocke, Vittorio Zanzani, Joke Deschildre, Ines Fernandez Maestre, Adrianna Amaro, Vanessa Vermeirssen, et al.
- Cell-free DNA as a diagnostic and prognostic biomarker in pediatric rhabdomyosarcoma(2023)
Authors: Nathalie S.M. Lak, Lieke M.J. van Zogchel, Lily Zappeij-Kannegieter, Ahmad Javadi, Ruben Van Paemel, Charlotte Vandeputte, Katleen De Preter, Bram De Wilde, Mathieu Chicard, Yasmine Iddir, et al.
- Performance evaluation of RNA purification kits and blood collection tubes in the Extracellular RNA Quality Control (exRNAQC) study(2023)
Authors: Anneleen Decock, Olivier De Wever, Celine Everaert, Hetty Helsmoortel, An Hendrix, Pieter Mestdagh, Annelien Morlion, Jo Vandesompele, Ruben Van Paemel, Francisco Avila Cobos, et al.
Number of pages: 1 - Performance evaluation of RNA purification kits and blood collection tubes in the Extracellular RNA Quality Control (exRNAQC) study(2023)
Authors: Anneleen Decock, Olivier De Wever, Celine Everaert, Hetty Helsmoortel, An Hendrix, Pieter Mestdagh, Annelien Morlion, Jo Vandesompele, Ruben Van Paemel, Francisco Avila Cobos, et al.
Number of pages: 1 - Mitotic dysregulation at tumor initiation creates a therapeutic vulnerability to combination anti-mitotic and pro-apoptotic agents for MYCN-driven neuroblastoma(2023)
Authors: Lei Zhai, Anushree Balachandran, Rebecca Larkin, Janith A. Seneviratne, Sylvia A. Chung, Amit Lalwani, Shoma Tsubota, Dominik Beck, Kenji Kadomatsu, Anneleen Beckers, et al.
- Dramatic impact of blood collection tube and RNA purification method on extracellular RNA transcriptomes(2023)
Authors: Jasper Anckaert, Francisco Avila Cobos, Anneleen Decock, Philippe Decruyenaere, Jill Deleu, Katleen De Preter, Olivier De Wever, Jilke De Wilde, Bert Dhondt, Thibaut D'huyvetter, et al.
Number of pages: 1 - Circulating immune cell dynamics as outcome predictors for immunotherapy in non-small cell lung cancer(2023)
Authors: Alvaro Marcos Rubio, Celine Everaert, Eufra Van Damme, Katleen De Preter, Karim Vermaelen
- Memory of stochastic single-cell apoptotic signaling promotes chemoresistance in neuroblastoma(2023)
Authors: Jordan F. Hastings, Sharissa L. Latham, Alvin Kamili, Madeleine S. Wheatley, Jeremy Z. R. Han, Marie Wong-Erasmus, Monica Phimmachanh, Max Nobis, Chiara Pantarelli, Antonia L. Cadell, et al.