Researcher
Kathleen Machiels
- Disciplines:Endocrinology and metabolic diseases, Gastro-enterology and hepatology, Biomarker discovery and evaluation, Drug discovery and development, Medicinal products, Pharmaceutics, Pharmacognosy and phytochemistry, Pharmacology, Pharmacotherapy, Toxicology and toxinology, Other pharmaceutical sciences
Affiliations
- Translational Research in GastroIntestinal Disorders (Division)
Member
From1 Aug 2009 → 3 Jan 2022
Projects
1 - 6 of 6
- CHARM: CHAracterization and ReMediation of a dysbiotic colon microbiota configurationFrom1 Jan 2020 → 31 Dec 2023Funding: FWO research project
- Microbiota modulation strategies in Inflammatory Bowel Disease managementFrom1 Oct 2019 → 1 Oct 2023Funding: Own budget, for example: patrimony, inscription fees, gifts
- Fecal microbiota transplant in ulcerative colitis patients: what is the role of the human gut virome and can it be used as a biomarker for predicting treatment succesFrom1 Oct 2018 → 22 Apr 2024Funding: FWO Strategic Basic Research Grant
- Therapeutic manipulation of the gut microbiome in inflammatory bowel diseaseFrom1 Aug 2016 → 9 Dec 2021Funding: Own budget, for example: patrimony, inscription fees, gifts
- Fecal microbiota transplantation in patients with ulcerative colitis: fecal donor selection and interplay between intestinal microbiota, diet and host geneticsFrom1 Jan 2016 → 31 Dec 2019Funding: FWO research project (including WEAVE projects)
- Functional, temporal and spatial variability of the intestinal microbiome in the pathogenesis of inflammatory bowel disease.From1 Oct 2014 → 3 Jan 2021Funding: FWO fellowships
Publications
31 - 40 of 46
- Neutrophil gelatinase B-associated lipocalin and matrix metalloproteinase-9 complex as a surrogate serum marker of mucosal healing in ulcerative colitis(2014)
Authors: Magali de Bruyn, Ingrid Arijs, Kathleen Machiels, Kristel Van Steen, Gert Van Assche, Marc Ferrante, Paul Rutgeerts, Séverine Vermeire, Ghislain Opdenakker
Pages: 1198 - 207 - Predominant Gut Microbiota Predict Pouchitis Following Colectomy and IPAA in Ulcerative Colitis(2014)
Authors: Kathleen Machiels, Marie Joossens, Ingrid Arijs, Isabelle Terrasson, Vera Ballet, Marc Ferrante, Jan Verhaegen, Kristel Van Steen, Anthony de Buck van Overstraeten, Albert Wolthuis, et al.
Pages: S832 - S833 - Infliximab restores the dysfunctional matrix remodeling protein and growth factor gene expression in patients with inflammatory bowel disease(2014)
Authors: Magali de Bruyn, Kathleen Machiels, Jennifer Vandooren, Bart Lemmens, Christine Breynaert, Jan Van der Goten, Dominiek Staelens, Thomas Billiet, Gert De Hertogh, Marc Ferrante, et al.
Pages: 339 - 52 - Butyricicoccus pullicaecorum in inflammatory bowel disease(2013)
Authors: Kathleen Machiels, Clementine Perrier, Séverine Vermeire
Pages: 1745 - 1752 - Mucosal Gene Expression Profiles in Pouchitis and in Active Ileal Crohn's Disease are Very Similar(2012)
Authors: Ingrid Arijs, Jan Van der Goten, Marc Ferrante, Kathleen Machiels, Vicky De Preter, Leentje Van Lommel, Gert Van Assche, Séverine Vermeire, Frans Schuit, Paul Rutgeerts
Pages: S879 - S879 - Mucosal Gene Expression Differences Between Early and Post-Operative Recurrent/Late Ileal Crohn's Disease Suggest Increased Inflammatory Load in Early Disease(2012)
Authors: Ingrid Arijs, Jan Van der Goten, Gert De Hertogh, Marc Ferrante, Kathleen Machiels, Leentje Van Lommel, Gert Van Assche, Séverine Vermeire, Frans Schuit, Paul Rutgeerts
Pages: S881 - S881 - Pilot Study on the Safety and Efficacy of Faecal Microbiota Transplantation in Refractory Crohn's Disease(2012)
Authors: Séverine Vermeire, Marie Joossens, Kristin Verbeke, Falk Hildebrand, Kathleen Machiels, Karolien Van den Broeck, Gert Van Assche, Paul Rutgeerts
Pages: S360 - S360 - Bacterial Dysbiosis in Ulcerative Colitis Patients Differs From Crohn's Disease Patients(2012)
Authors: Kathleen Machiels, Marie Joossens, Joao Sabino, Vicky De Preter, Ingrid Arijs, Vera Ballet, Karolien Claes, Jan Verhaegen, Gert Van Assche, Paul Rutgeerts, et al.
Pages: S46 - S46 - Effects of haptoglobin polymorphisms and deficiency on susceptibility to inflammatory bowel disease and on severity of murine colitis(2012)
Authors: Isabelle Cleynen, Gert De Hertogh, Kristel Van Steen, Kathleen Machiels, Clementine Perrier, Vera Ballet, Marc Ferrante, Liesbet Henckaerts, Paul Rutgeerts, Jan Ceuppens, et al.
Pages: 528 - 534 - The heat shock protein 90 inhibitor IPI-504 induces KIT degradation, tumor shrinkage and cell proliferation arrest in xenografts models of gastrointestinal stromal tumors(2011)
Authors: Beppe Floris, Maria Debiec-Rychter, Agnieszka Wozniak, Kathleen Machiels, Raf Sciot, Patrick Schöffski
Pages: 1897 - 1908