Researcher
Kathleen Machiels
- Disciplines:Endocrinology and metabolic diseases, Gastro-enterology and hepatology, Biomarker discovery and evaluation, Drug discovery and development, Medicinal products, Pharmaceutics, Pharmacognosy and phytochemistry, Pharmacology, Pharmacotherapy, Toxicology and toxinology, Other pharmaceutical sciences
Affiliations
- Translational Research in GastroIntestinal Disorders (Division)
Member
From1 Aug 2009 → 3 Jan 2022
Projects
1 - 6 of 6
- CHARM: CHAracterization and ReMediation of a dysbiotic colon microbiota configurationFrom1 Jan 2020 → 31 Dec 2023Funding: FWO research project
- Microbiota modulation strategies in Inflammatory Bowel Disease managementFrom1 Oct 2019 → 1 Oct 2023Funding: Own budget, for example: patrimony, inscription fees, gifts
- Fecal microbiota transplant in ulcerative colitis patients: what is the role of the human gut virome and can it be used as a biomarker for predicting treatment succesFrom1 Oct 2018 → 22 Apr 2024Funding: FWO Strategic Basic Research Grant
- Therapeutic manipulation of the gut microbiome in inflammatory bowel diseaseFrom1 Aug 2016 → 9 Dec 2021Funding: Own budget, for example: patrimony, inscription fees, gifts
- Fecal microbiota transplantation in patients with ulcerative colitis: fecal donor selection and interplay between intestinal microbiota, diet and host geneticsFrom1 Jan 2016 → 31 Dec 2019Funding: FWO research project (including WEAVE projects)
- Functional, temporal and spatial variability of the intestinal microbiome in the pathogenesis of inflammatory bowel disease.From1 Oct 2014 → 3 Jan 2021Funding: FWO fellowships
Publications
11 - 20 of 46
- SERUM PROTEOMIC PROFILING REVEALS CHANGES IN INFLAMMATORY PROFILES WITH CONSECUTIVE BIOLOGICAL THERAPIES IN PATIENTS WITH INFLAMMATORY BOWEL DISEASE(2018)
Authors: Sare Verstockt, Bram Verstockt, Gert Van Assche, Marc Ferrante, Kathleen Machiels, Séverine Vermeire
Pages: S1023 - S1023 - DISCRIMINATION OF ENDOSCOPIC POSTOPERATIVE RECURRENCE IN PATIENTS WITH CROHN'S DISEASE USING SEROLOGICAL INFLAMMATORY MARKERS(2018)
Authors: Kathleen Machiels, Sare Verstockt, Bram Verstockt, Gert Van Assche, Albert Wolthuis, André D'Hoore, Marc Ferrante, Séverine Vermeire
Pages: S586 - S587 - Effect of vedolizumab (anti-alpha 4 beta 7-integrin) therapy on histological healing and mucosal gene expression in patients with UC(2018)
Authors: Ingrid Arijs, Gert De Hertogh, Bart Lemmens, Magali de Bruyn, Wiebe Vanhove, Isabelle Cleynen, Kathleen Machiels, Marc Ferrante, Frans Schuit, Gert Van Assche, et al.
Pages: 43 - 52 - Dysregulated gene and miRNA expression in different stages of Crohn’s disease(2017)
Authors: Isabelle Cleynen, Sare Verstockt, Gert De Hertogh, Jan Van der Goten, Maaike Vancamelbeke, Bram Verstockt, Kathleen Machiels, Leentje Van Lommel, Frans Schuit, Paul Rutgeerts, et al.
- Low eukaryotic viral richness is associated with faecal microbiota transplantation success in patients with UC(2017)
Authors: Ward Deboutte, Tim Dierckx, Kathleen Machiels, Jun Wang, Kwe Claude Yinda, Piet Maes, Marc Van Ranst, Marie Joossens, Jeroen Raes, Séverine Vermeire, et al.
Pages: 1558 - + - IMPACT OF ILEOCECAL RESECTION IN CROHN'S DISEASE PATIENTS ON FECAL MICROBIOTA(2017)
Authors: Kathleen Machiels, Victoria Pascal, Joao Sabino, Alba Santiago, David Campos, Albert Wolthuis, Anthony de Buck van Overstraeten, André D'Hoore, Gert Van Assche, Marc Ferrante, et al.
Pages: S989 - S990 - MUCOSAL RECOLONIZATION AFTER ILEOCECAL RESECTION DIFFERS IN CROHN'S DISEASE PATIENTS DEVELOPING POSTOPERATIVE RECURRENCE(2017)
Authors: Kathleen Machiels, Marta Pozuelo del Rio, Joao Sabino, Alba Santiago, David Campos, Albert Wolthuis, Anthony de Buck van Overstraeten, André D'Hoore, Gert Van Assche, Marc Ferrante, et al.
Pages: S990 - S990 - Relationship between microbiota and development of early postoperative Crohn's disease recurrence(2017)
Authors: Kathleen Machiels, V Pascal, J Sabino, A Santiago, D Campos, Albert Wolthuis, A De Buck van Overstraeten, André D'Hoore, Gert Van Assche, Marc Ferrante, et al.
Pages: S53 - S53 - Impact of ileocecal resection in Crohn's disease patients on mucosal microbiota(2017)
Authors: Kathleen Machiels, M Pozuelo del Ro, J Sabino, A Santiago, D Campos, Albert Wolthuis, A De Buck van Overstraeten, André D'Hoore, Gert Van Assche, Marc Ferrante, et al.
Pages: S24 - S25 - Specific members of the predominant gut microbiota predict pouchitis following colectomy and IPAA in UC(2017)
Authors: Kathleen Machiels, João Guedelha Sabino, Leen Vandermosten, Marie Joossens, Ingrid Arijs, Magali de Bruyn, Gert Van Assche, Marc Ferrante, Jan Verhaegen, Kristel Van Steen, et al.
Pages: 79 - 88