Researcher
Kathleen Claes
- Keywords:inherited predisposition for cancer
- Disciplines:Immunogenetics, Clinical genetics and molecular diagnostics, Epigenetics, Genetics, Cancer prevention, Cancer diagnosis, Oncology not elsewhere classified, Molecular diagnostics
Affiliations
- Department of Biomolecular Medicine (Department)
Member
From1 Oct 2018 → Today - Department of Pediatrics and medical genetics (Department)
Member
From1 Mar 1997 → 30 Sep 2018
Infrastructure
1 - 1 of 1
Projects
1 - 10 of 16
- Multi-omics approach to identify pancreatic cancer biomarkers in liquid biopsies of advanced stage patients by pioneering single cell mass spectrometry of CTCs and (epi)genetics characterization of cfDNAFrom1 Oct 2023 → TodayFunding: BOF - projects
- Joint Action on Networks of ExpertiseFrom1 Oct 2022 → TodayFunding: Other EU initiatives out of framework
- Cofunding core facility - UGent NGS CoreFrom1 Jul 2022 → TodayFunding: BOF - research organisations
- In vivo functional evaluation of unclassified variants, found in the breast cancer gene BRCA2, using CRISPR-mediated genome editing in zebrafishFrom15 Nov 2021 → TodayFunding: BOF - doctoral mandates
- Diagnosing HEreditary predisposition syndromes for Childhood cancer: Implementation in clinical PRactice (DHECIPR)From1 Jan 2021 → TodayFunding: FWO Applied Biomedical Research (TBM)
- CONDITIONAL: COvid-19: iNterplay between genetic preDisposITION and immunologicAl LandscapeFrom15 Apr 2020 → 14 Apr 2021Funding: BOF - projects
- Heading towards an in vivo predictive test for personalized ovarian cancer treatment: application of novel therapies in zebrafish patient derived xenograftsFrom1 Nov 2019 → TodayFunding: FWO Strategic Basic Research Grant
- RAPID - Radiosensitivity Analysis for patients with a Primary Immunodeficiency DiseaseFrom1 Oct 2018 → 30 Sep 2022Funding: FWO Applied Biomedical Research (TBM)
- Immunomonitoring of patients with non-small cell lung carcinoma treated with a tumor mutanome-targeted dendritic cell vaccineFrom1 Jan 2018 → 31 Dec 2021Funding: BOF - Doctoral projects
- Pancreatic cancer: hope to improve prognosis through thorough analysis of DNA and RNA markers for diagnosis and therapy monitoring in liquid biopsiesFrom1 Sep 2017 → 31 Dec 2023Funding: Nonprofit institution or equivalents
Publications
11 - 20 of 80
- Application of an ultrasensitive NGS-based blood test for the diagnosis of early-stage lung cancer : sensitivity, a hurdle still difficult to overcome(2022)
Authors: Malaïka Van der Linden, Bram Van Gaever, Lennart Raman, Karim Vermaelen, Ingel Demedts, Veerle Surmont, Ulrike Himpe, Yolande Lievens, Liesbeth Ferdinande, Franceska Dedeurwaerdere, et al.
- Genotype-phenotype associations in a large PTEN Hamartoma Tumor Syndrome (PHTS) patient cohort(2022)
Authors: Linda A. J. Hendricks, Nicoline Hoogerbrugge, Hanka Venselaar, Stefan Aretz, Isabel Spier, Eric Legius, Hilde Brems, Robin de Putter, Kathleen Claes, Gareth Evans, et al.
- Genetic testing in prostate cancer in clinical practice(2021)
Authors: Robin de Putter, Bram De Laere, Piet Ost, Kathleen Claes
Pages: 156 - 163 - Frequency of participation in external quality assessment programs focused on rare diseases : Belgian guidelines for human genetics centers(2021)
Authors: Josephine Lantoine, Anne Brysse, Vinciane Dideberg, Kathleen Claes, Sofie Symoens, Wim Coucke, Valerie Benoit, Sonia Rombout, Martine De Rycke, Sara Seneca, et al.
- Pathogenic neurofibromatosis type 1 (NF1) RNA splicing resolved by targeted RNAseq(2021)
Authors: R. Koster, R. D. Brandao, D. Tserpelis, C. E. P. van Roozendaal, C. N. van Oosterhoud, Kathleen Claes, A. D. C. Paulussen, M. Sinnema, M. Vreeburg, V van der Schoot, et al.
- Integration of genomics and transcriptomics to identify DNA damage defects in PID patients prone to cancer(2021)
Authors: Lynn Backers, Bram Parton, Mattias Van Heetvelde, Marieke De Bruyne, Kim De Leeneer, Anne Vral, Filomeen Haerynck, Kathleen Claes
Number of pages: 1 - Prevalence of germline pathogenic variants in cancer predisposing genes in Czech and Belgian pancreatic cancer patients(2021)
Authors: Greet Wieme, Jan Kral, Toon Rosseel, Petra Zemankova, Bram Parton, Michal Vocka, Mattias Van Heetvelde, Petra Kleiblova, Bettina Blaumeiser, Jana Soukupova, et al.
Number of pages: 1 - The predictive ability of the 313 variant-based polygenic risk score for contralateral breast cancer risk prediction in women of European ancestry with a heterozygous BRCA1 or BRCA2 pathogenic variant(2021)
Authors: Inge M. M. Lakeman, Alexandra J. van den Broek, Julien A. M. Vos, Daniel R. Barnes, Julian Adlard, Irene L. Andrulis, Adalgeir Arason, Norbert Arnold, Banu K. Arun, Judith Balmana, et al.
Pages: 1726 - 1737 - Hereditary syndromes and pancreatic cancer(2021)
Authors: Kathleen Claes, Laura Pölsler, Johannes Zschocke
Pages: 29 - 49 - Dealing with pseudogenes in in the next generation sequencing era(2021)Edition: 2Series: Methods in Molecular Biology
Authors: Kathleen Claes, Toon Rosseel, Kim De Leeneer, Laura Poliseno
Pages: 363 - 381