Researcher
Karim Vermaelen
- Keywords:immunology, Immuno-oncology, oncology, respiratory medicine
- Disciplines:Immunology not elsewhere classified, Cancer therapy, Cancer biology, Applied immunology, Immunomodulation therapy, Respiratory medicine, Cell therapy, Vaccinology, Oncology not elsewhere classified, Medical transcriptomics
Affiliations
- Department of Internal Medicine and Pediatrics (Department)
Member
From1 Oct 2018 → Today - Department of Internal medicine (Department)
Member
From1 Jan 1998 → 30 Sep 2018
Projects
1 - 10 of 32
- REACTION: A modular mRNA-encoded artificial receptor for focused re-ignition of anti-cancer immune responsesFrom1 Oct 2023 → TodayFunding: BOF - projects
- TARgeted Mrna re-engineering for enhanced Antibody and Cellular immunity (TARMAC)From15 Apr 2023 → TodayFunding: IOF - technology concept exploration
- HIGH-THROUGHPUT, HIGH-SENSITIVITY AND COST-EFFECTIVE MONITORING OF INNATE AND ADAPTIVE IMMUNE RESPONSES AT SINGLE CELL LEVELFrom15 Dec 2022 → TodayFunding: BOF - scientific equipment program
- Re-engineering vesicle sorting signals of the mannose-6-phosphate receptor in an mRNA-vaccine approach to enable full anti-cancer T-cell engagementFrom1 Nov 2022 → 31 Oct 2023Funding: Nonprofit institution or equivalents
- A patient derived xenograft (PDX) platform for in vivo evaluation of novel anticancer therapiesFrom1 May 2022 → TodayFunding: FWO Medium Size Research Infrastructure
- Dendritic Cell Immunotherapy In Lung CancerFrom1 Nov 2021 → 31 Oct 2022Funding: Nonprofit institution or equivalents
- SparXells: Enabling next-generation Dendritic Cell Therapy in Lung Cancer and beyondFrom1 Aug 2021 → 31 Jul 2023Funding: IWT / VLAIO personal funding - innovation mandates
- BioGelator for local immunotherapyFrom15 Jul 2021 → TodayFunding: IOF - technology validation in lab
- Proteomics-derived epitopes for dramatically improved anticancer and antibacterial vaccine developmentFrom1 Jan 2021 → TodayFunding: BOF - projects
- SparXells™ : Enabling Next-Generation Dendritic Cell Therapy in Lung cancer and BeyondFrom15 Oct 2020 → 31 Dec 2022Funding: IOF - technology validation in real environment
Publications
11 - 20 of 71
- Vaccine strategies to improve anti-cancer cellular immune responses(2019)
Authors: Karim Vermaelen
- Immunoengineering through cancer vaccines - A personalized and multi-step vaccine approach towards precise cancer immunity(2018)
Authors: Lien Lybaert, Karim Vermaelen, Bruno De Geest, Lutz Nuhn
Pages: 125 - 145 - An unusual presentation of a case of human psittacosis(2018)
Authors: Yannick Vande Weygaerde, Charlot Versteele, Elke Thijs, Anton De Spiegeleer, Eva Van Braeckel, Karim Vermaelen
Pages: 138 - 142 - Invasive aspergillosis mimicking metastatic lung cancer(2018)
Authors: Michiel Vanfleteren, Anne-Marie C Dingemans, Veerle Surmont, Karim Vermaelen, Alida A Postma, Astrid ML Oude lashof, Cordula CM Pitz, Lizza EL Hendriks
- An accelerated, clinical-grade protocol to generate high yields of type 1-polarizing messenger RNA loaded dendritic cells for cancer vaccination(2018)
Authors: Elisabeth Brabants, S De Smet, Pam Devreker, Nancy De Cabooter, Veronique Debacker, Melissa Dullaers, JP Van Meerbeeck, Karim Vermaelen
Pages: 1164 - 1181 - The transcriptome of lung tumor-infiltrating dendritic cells reveals a tumor-supporting phenotype and a microRNA signature with negative impact on clinical outcome(2017)
Authors: Lotte Pyfferoen, Elisabeth Brabants, Nancy De Cabooter, Kim Deswarte, Manon Vanheerswynghels, Sofie De Prijck, Glenn Waegemans, Melissa Dullaers, Pieter Mestdagh, Karim Vermaelen
- Polyelectrolyte-enrobed cancer cells in view of personalized immune-therapy(2017)
Authors: Lien Lybaert, Keun Ah Ryu, Alfred C Chon, Karim Vermaelen, Aaron Esser-Kahn, Bruno De Geest
- Biomarkers for early diagnosis of malignant mesothelioma : do we need another moonshot?(2017)
Authors: Sabrina Lagniau, Kevin Lamote, Jan Van Meerbeeck, Karim Vermaelen
Pages: 53751 - 53762 - The role of dicer in alveolar macrophages and dendritic cells in smoke-induced inflammation(2017)Volume: 195
Authors: Elise De Smet, Pieter Mestdagh, S Provoost, Karim Vermaelen
Number of pages: 1 - The immunophenotypic fingerprint of patients with primary antibody deficiencies is partially present in their asymptomatic first-degree relatives(2017)
Authors: Delfien Bogaert, Marieke De Bruyne, Veronique Debacker, Pauline Depuydt, Jan Philippé, Victoria Bordon Maria, Andrea Cerutti, Karim Vermaelen, Filomeen Haerynck, Melissa Dullaers
Pages: 192 - 202