Researcher
Karim Vermaelen
- Keywords:immunology, Immuno-oncology, oncology, respiratory medicine
- Disciplines:Immunology not elsewhere classified, Cancer therapy, Cancer biology, Applied immunology, Immunomodulation therapy, Respiratory medicine, Cell therapy, Vaccinology, Oncology not elsewhere classified, Medical transcriptomics
Affiliations
- Department of Internal Medicine and Pediatrics (Department)
Member
From1 Oct 2018 → Today - Department of Internal medicine (Department)
Member
From1 Jan 1998 → 30 Sep 2018
Projects
1 - 10 of 32
- REACTION: A modular mRNA-encoded artificial receptor for focused re-ignition of anti-cancer immune responsesFrom1 Oct 2023 → TodayFunding: BOF - projects
- TARgeted Mrna re-engineering for enhanced Antibody and Cellular immunity (TARMAC)From15 Apr 2023 → 14 Apr 2024Funding: IOF - technology concept exploration
- HIGH-THROUGHPUT, HIGH-SENSITIVITY AND COST-EFFECTIVE MONITORING OF INNATE AND ADAPTIVE IMMUNE RESPONSES AT SINGLE CELL LEVELFrom15 Dec 2022 → TodayFunding: BOF - scientific equipment program
- Re-engineering vesicle sorting signals of the mannose-6-phosphate receptor in an mRNA-vaccine approach to enable full anti-cancer T-cell engagementFrom1 Nov 2022 → 31 Oct 2023Funding: Nonprofit institution or equivalents
- A patient derived xenograft (PDX) platform for in vivo evaluation of novel anticancer therapiesFrom1 May 2022 → TodayFunding: FWO Medium Size Research Infrastructure
- Dendritic Cell Immunotherapy In Lung CancerFrom1 Nov 2021 → 31 Oct 2022Funding: Nonprofit institution or equivalents
- SparXells: Enabling next-generation Dendritic Cell Therapy in Lung Cancer and beyondFrom1 Aug 2021 → 31 Jul 2023Funding: IWT / VLAIO personal funding - innovation mandates
- BioGelator for local immunotherapyFrom15 Jul 2021 → TodayFunding: IOF - technology validation in lab
- Proteomics-derived epitopes for dramatically improved anticancer and antibacterial vaccine developmentFrom1 Jan 2021 → TodayFunding: BOF - projects
- SparXells™ : Enabling Next-Generation Dendritic Cell Therapy in Lung cancer and BeyondFrom15 Oct 2020 → 31 Dec 2022Funding: IOF - technology validation in real environment
Publications
1 - 10 of 71
- Circulating immune cell dynamics as outcome predictors for immunotherapy in non-small cell lung cancer(2023)
Authors: Alvaro Marcos Rubio, Celine Everaert, Eufra Van Damme, Katleen De Preter, Karim Vermaelen
- Headspace volatile organic compound profiling of pleural mesothelioma and lung cancer cell lines as translational bridge for breath research(2022)
Authors: Eline Janssens, Zoë Mol, Lore Vandermeersch, Sabrina Lagniau, Karim Vermaelen, Jan Van Meerbeeck, Christophe Walgraeve, Elly Marcq, Kevin Lamote
- Application of an ultrasensitive NGS-based blood test for the diagnosis of early-stage lung cancer : sensitivity, a hurdle still difficult to overcome(2022)
Authors: Malaïka Van der Linden, Bram Van Gaever, Lennart Raman, Karim Vermaelen, Ingel Demedts, Veerle Surmont, Ulrike Himpe, Yolande Lievens, Liesbeth Ferdinande, Franceska Dedeurwaerdere, et al.
- Small-scale manufacturing of neoantigen-encoding messenger RNA for early-phase clinical trials(2022)
Authors: Rupert Mayer, Pam Devreker, Karin Weening, Nele Lootens, Saskia De Smet, Marieke Brusseel, Stijn De Munter, Lore Billiet, Glenn Goetgeluk, Hanne Jansen, et al.
Pages: 213 - 222 - Treatment of a patient with severe cytomegalovirus (CMV) infection after haploidentical stem cell transplantation with donor-derived CMV-specific T cells(2021)
Authors: Saskia De Smet, Kelly Heyns, Nele Lootens, Jonas Segaert, Tom Taghon, Georges Leclercq, Karim Vermaelen, Evelyne Willems, Etienne Baudoux, Frédéric Baron
Pages: 482 - 486 - The RNA Atlas expands the catalog of human non-coding RNAs (June, 10.1038/s41587-021-00936-1, 2021)(2021)
Authors: Lucia Lorenzi, Hua-Sheng Chiu, Francisco Avila Cobos, Stephen Gross, Justine Nuytens, Katrien Vanderheyden, Aidan Tay, Eric J. de Bony, Fien Gysens, Marieke Vromman, et al.
Pages: 1467 - 1467 - The RNA Atlas expands the catalog of human non-coding RNAs(2021)
Authors: Lucia Lorenzi, Hua-Sheng Chiu, Francisco Avila Cobos, Stephen Gross, Pieter-Jan Volders, Robrecht Cannoodt, Justine Nuytens, Katrien Vanderheyden, Jasper Anckaert, Steve Lefever, et al.
Pages: 1453 - 1465 - mRNA in cancer immunotherapy : beyond a source of antigen(2021)
Authors: Lien Van Hoecke, Rein Verbeke, Heleen Dewitte, Ine Lentacker, Karim Vermaelen, Karine Breckpot, Sandra Van Lint
- Shallow whole-genome sequencing of plasma cell-free DNA accurately differentiates small from non-small cell lung carcinoma(2020)
Authors: Lennart Raman, Malaïka Van der Linden, Kim Van der Eecken, Karim Vermaelen, Ingel Demedts, Veerle Surmont, Ulrike Himpe, Franceska Dedeurwaerdere, Liesbeth Ferdinande, Yolande Lievens, et al.
- Blood-based test for diagnosis and functional subtyping of familial Mediterranean fever(2020)
Authors: Hanne Van Gorp, Linyan Huang, Pedro Henrique Viana Saavedra, Marnik Vuylsteke, Tomoko Asaoka, Giusi Prencipe, Antonella Insalaco, Benson Ogunjimi, Jerold Jeyaratnam, Ilaria Cataldo, et al.
Pages: 960 - 968