Researcher
Karen Vanhoorelbeke
- Disciplines:Biochemistry and metabolism, Cardiac and vascular medicine, Medical biochemistry and metabolism
Affiliations
- Chemistry, Kulak Kortrijk Campus (Department)
Responsible
From1 Oct 2018 → Today - Chemistry, Kulak Kortrijk Campus (Department)
Member
From1 Jan 2009 → Today - Faculty of Medicine (Faculty)
Member
From1 Oct 2004 → 30 Sep 2006 - Faculty of Science, Kulak Kortrijk Campus (Faculty)
Member
From1 Oct 2000 → 31 Dec 2008
Projects
1 - 10 of 58
- B-specific: B-cell related gene and protein markers with prognostic and therapeutic value for CVDFrom1 Oct 2023 → TodayFunding: Horizon Europe - European Innovation Council (EIC)
- A novel targeted therapy to treat bleeding in patients with a left ventricular assist device.From1 May 2023 → TodayFunding: IOF - mandates
- Universal Chimeric Antigen Receptor (UniCAR) T-cell therapy: an innovative treatment for autoimmune diseaseFrom5 Apr 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Universal chimeric antigen receptor (uniCAR)-T cell therapy to treat autoimmune diseases: immune mediated thrombotic thrombocytopenic purpura as a model system.From1 Mar 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Flow cytometer for the Interdisciplinary Research Facility Life Sciences at Campus Kulak KortrijkFrom1 Jan 2023 → TodayFunding: BOF - scientific equipment program
- Allosteric ADAMTS13 activation: elucidating long-range structural crosstalk bringing the enzyme in a preactivated stateFrom1 Jan 2023 → TodayFunding: FWO research project (including WEAVE projects)
- An integrated approach to restore tolerance in autoimmune diseaseFrom1 Oct 2022 → TodayFunding: HORIZON.1.2 - Marie Skłodowska-Curie-actions (MSCA)
- Next-generation DNA vectors to improve efficacy, precision and accessibility of antibody gene transferFrom15 Mar 2022 → 14 Mar 2024Funding: BOF - various
- Innovative approaches to tackle autoimmune diseases: immune-mediated thrombotic thrombocytopenic purpura as a disease modelFrom1 Jul 2021 → 30 Jun 2023Funding: BOF - various
- A novel biomarker to improve the quality of life of immune mediatied thrombotic thrombocytopenic purpura patients.From1 Jun 2021 → 31 May 2023Funding: Foreign foundations, funds with scientific view
Publications
151 - 160 of 210
- Analysis of thrombogenicity under flow reveals new insights into the prothrombotic state of patients with post-COVID syndrome
Authors: Karen Vanhoorelbeke
Pages: 94 - 100 - Generation and validation of small ADAMTS13 fragments for epitope mapping of anti-ADAMTS13 autoantibodies in immune-mediated thrombotic thrombocytopenic purpura
Authors: Kadri Kangro, Elien Roose, Simon De Meyer, Karen Vanhoorelbeke
Pages: 918 - 930 - Endogenous plasmin levels control the development of acute episodes of thrombotic thrombocytopenic purpura in mice
Authors: Claudia Tersteeg, Louis Deforche, Ann Gils, Hans Deckmyn, Paul Declerck, H Rottensteiner, C Maas, Simon De Meyer, Karen Vanhoorelbeke
Pages: 153 - 153 - ADAMTS13's tail tale: Developing antibodies to reveal novel insights
Authors: Louis Deforche, Karen Vanhoorelbeke, Simon De Meyer, Wim Maes
Number of pages: 220 - Dissecting the pathophysiology of immune thrombotic thrombocytopenic purpura: interplay between genes and environmental triggers (vol 103, pg 1099, 2018)
Authors: Johana Hrdinova, Silvia D'Angelo, Nuno AG Grata, Bogac Ercig, Karen Vanhoorelbeke, Agnes Veyradier, Jan Voorberg, Paul Coppo
Pages: 924 - 924 - Active platelet-binding conformation of plasma von willebrand factor in young women with acute myocardial infarction
Authors: Hendrik Feys, Karen Vanhoorelbeke
Pages: 1653 - 1656 - Snelle en makkelijk uitvoerbare FO-SPR-gebaseerde laboratoriumtesten voor VWF antigen en functionaliteit en inzichten in de vaccin-geïnduceerde adaptieve immuunrespons tegen SARS-CoV-2
Authors: Bas Calcoen, Simon De Meyer, Karen Vanhoorelbeke, Marc Jacquemin, Wim Maes
- ADAMTS13 and anti-ADAMTS13 antibodies as markers for recurrence of acquired thrombotic thrombocytopenic purpura during remission
Authors: Hendrik Feys, Karen Vanhoorelbeke
Pages: 232 - 239 - Regulation of VWF Cleavage Is Mediated By Coupling ADAMTS13 D- and C- Domain Binding Sites
Authors: Karen Vanhoorelbeke
Pages: 5580 - 5581 - Inhibitors of the interactions between collagen and its receptors on platelets
Authors: Hans Deckmyn, Simon De Meyer, Katleen Broos, Karen Vanhoorelbeke
Pages: 311 - 337
Patents
1 - 9 of 9
- Haemorrhagic disorder due to ventricular assist device (Inventor)
- Humanised adamts13 binding antibodies (Inventor)
- Screening and sorting of single cells (Inventor)
- Anti adamts13 antibodies and their use for treatment or prevention of haemorrhagic disorders due to ventricular assist device (Inventor)
- Humanised adamts13 binding antibodies (Inventor)
- Screening and sorting of single cells (Inventor)
- Haemorrhagic disorder due to ventricular assist device (Inventor)
- Humanised adamts13 binding antibodies (Inventor)
- Anti adamts13 antibodies and their use for treatment or prevention of haemorrhagic disorders due to ventricular assist device (Inventor)