Researcher
Karen Sermon
- Keywords:Medicine
- Disciplines:Stem cell biology, Developmental biology, Reproductive medicine, Genetics
Affiliations
- Reproduction and Genetics (Research group)
Responsible
From1 Oct 1988 → Today - Basic (bio-) Medical Sciences (Department)
Member
From1 Jan 2024 → Today - Basic (bio-) Medical Sciences (Department)
Member
From1 Apr 2022 → Today - Basic (bio-) Medical Sciences (Department)
Member
From8 Apr 2019 → Today - Basic (bio-) Medical Sciences (Department)
Member
From1 Jan 2014 → 20 Oct 2022 - Department of Embryology and Genetics (Department)
Member
From1 Jul 2004 → 31 Dec 2013 - Medical Imaging and Physical Sciences (Department)
Member
From1 Oct 2003 → 30 Jun 2004 - Department of Embryology and Genetics (Department)
Member
From1 Oct 1997 → 30 Sep 2006 - Centre for Medical Genetics (Research group)
Member
From1 Feb 1996 → 30 Sep 1997
Projects
11 - 20 of 26
- Do children born after intracytoplasmic sperm injection have an increased risk of mutations in mitochondrial DNA?From1 Jan 2017 → 31 Dec 2017Funding: FWO research grant KAN
- The effect of maternal decidualization on the development of the blastocyst in humansFrom1 Jan 2017 → 31 Dec 2017Funding: FWO research grant KAN
- FWO-SB-Scholarship: defining the molecular basis for liver cell differentiation deficiency in human pluripotent stem cellsFrom1 Jan 2017 → 31 Dec 2020Funding: FWO fellowships
- SEGa - The Science and Ethics of stem cell-derived GametesFrom1 Feb 2016 → 31 Jan 2020Funding: IWT / VLAIO - excluding impulse programmes
- Identification of molecular regulators of differentiation potential in human embryonic stem cells.From1 Oct 2015 → 30 Sep 2019Funding: FWO fellowships
- Human pluripotent stem cells as disease models for trinucleotide instability in myotonic dystrophy type IFrom1 Jan 2015 → 31 Dec 2018Funding: FWO research project (including WEAVE projects)
- Human pluripotent stem cells as models for diseaseFrom1 Oct 2014 → 30 Sep 2015Funding: University - Project driven research
- Totipotency versus fate in human embryonic stem cellsFrom1 Jan 2014 → 31 Dec 2017Funding: FWO research project (including WEAVE projects)
- (In)stability of X chromosome inactivation in human pluripotent stem cellsFrom1 Jan 2012 → 31 Dec 2012Funding: FWO research grant KAN
- Chromosomal abnormalities in human preimplantation embryos and embryonic stem cells: causes, mechanisms and consequences for IVF and regenerative medicineFrom1 Jan 2010 → 31 Dec 2013Funding: FWO research project (including WEAVE projects)
Publications
1 - 10 of 68
- Children born after assisted reproduction more commonly carry a mitochondrial genotype associating with low birthweight(2024)
Authors: Claudia Spits, Joke Mertens, Florence Belva, Aafke PA van Montfoort, Marius Regin, Filippo Zambelli, Sara Seneca, Edouard Couvreu De Deckersberg, Maryse Bonduelle, Herman Tournaye, et al.
- SALL3 mediates the loss of neuroectodermal differentiation potential in human embryonic stem cells with chromosome 18q loss(2024)
Authors: Claudia Spits, Yingnan Lei, Diana Al Delbany, Nusa Krivec, Marius Regin, Edouard Couvreu De Deckersberg, Charlotte Janssens, Manjusha S Ghosh, Karen Sermon
Pages: 562-578 - Genetics of infertility: a paradigm shift for medically assisted reproduction(2023)
Authors: W Verpoest, Özlem Okutman, Annelore Van Der Kelen, Karen Sermon, Stéphane Viville
Pages: 2289-2295 - Lineage segregation in human pre-implantation embryos is specified by YAP1 and TEAD1(2023)
Authors: Marius Regin, Wafaa Essahib, Andrej Demtschenko, Delphine Dewandre, Laurent David, Claudia Gerri, Kathy K Niakan, G Verheyen, Herman Tournaye, Johan Sterckx, et al.
Pages: 1484-1498 - A systematic review and evidence assessment of monogenic gene-disease relationships in human female infertility and differences in sex development(2023)
Authors: Annelore Van Der Kelen, Özlem Okutman, Elodie Javey, Münevver Serdarogullari, Charlotte Janssens, Manjusha S Ghosh, Bart J H Dequeker, Florence Perold, Claire Kastner, Emmanuelle Kieffer, et al.
Pages: 218-232 - #ESHREjc report(2023)
Authors: Sofia Makieva, Juan J Fraire-Zamora, Mina Mincheva, Julia Uraji, Zoya E Ali, Omar F Ammar, George Liperis, Munevver Serdarogullari, Enrica Bianchi, Jonathan Pettitt, et al.
Pages: 324-327 - Mitochondrial DNA variants segregate during human preimplantation development into genetically different cell lineages that are maintained postnatally(2022)
Authors: Joke Mertens, Marius Regin, Neelke De Munck, Edouard Couvreu De Deckersberg, Florence Belva, Karen Sermon, Herman Tournaye, Christophe Blockeel, Hilde Van de Velde, Claudia Spits
Pages: 3629-3642 - Impaired catabolism of free oligosaccharides due to MAN2C1 variants causes a neurodevelopmental disorder(2022)
Authors: Nuno M. M. Maia, Sven Potelle, Hamide Yildirim, Sandrine Duvet, Shyam K. Akula, Celine Schulz, Elsa Wiame, Alexander Gheldof, Katherine O'kane, Abbe Lai, et al.
Pages: 345-360 - Myotonic dystrophy type 1 embryonic stem cells show decreased myogenic potential, increased CpG methylation at the DMPK locus and RNA mis-splicing(2022)
Authors: Silvie Franck, Edouard Couvreu De Deckersberg, Jodi L Bubenik, Christina Markouli, Lise Barbé, Joke Allemeersch, Pierre Hilven, Geoffrey Duqué, Maurice S Swanson, Alexander Gheldof, et al.
- ESHRE survey results and good practice recommendations on managing chromosomal mosaicism(2022)
Authors: M De Rycke, Antonio Capalbo, Edith Coonen, Giovanni Coticchio, Francesco Fiorentino, Veerle Goossens, Saria Mcheik, Carmen Rubio, Karen Sermon, Ioannis Sfontouris, et al.