Researcher
Karen Sermon
- Keywords:Medicine
- Disciplines:Stem cell biology, Developmental biology, Reproductive medicine, Genetics
Affiliations
- Reproduction and Genetics (Research group)
Responsible
From1 Oct 1988 → Today - Basic (bio-) Medical Sciences (Department)
Member
From1 Jan 2024 → Today - Basic (bio-) Medical Sciences (Department)
Member
From1 Apr 2022 → Today - Basic (bio-) Medical Sciences (Department)
Member
From8 Apr 2019 → Today - Basic (bio-) Medical Sciences (Department)
Member
From1 Jan 2014 → 20 Oct 2022 - Department of Embryology and Genetics (Department)
Member
From1 Jul 2004 → 31 Dec 2013 - Medical Imaging and Physical Sciences (Department)
Member
From1 Oct 2003 → 30 Jun 2004 - Department of Embryology and Genetics (Department)
Member
From1 Oct 1997 → 30 Sep 2006 - Centre for Medical Genetics (Research group)
Member
From1 Feb 1996 → 30 Sep 1997
Projects
1 - 10 of 26
- The Genetic Component to Infertility and Early Developmental FailureFrom1 Jan 2023 → TodayFunding: BOF - Methusalem
- Identifying causes of emergence of chromosomal abnormalities in human cleavage stage embryos.From1 Nov 2022 → TodayFunding: FWO fellowships
- Exploring the first lineage segregation in the human embryo: is GATA3 the gatekeeper of trophectoderm differentiation?From1 Jan 2022 → TodayFunding: FWO research project (including WEAVE projects)
- The impact of recurrent chromosomal abnormalities on growth advantage and differentiation capacity of human pluripotent stem cellsFrom1 Nov 2020 → TodayFunding: FWO fellowships
- The search for the origin of chromosomal abnormalities in human preimplantation embryosFrom1 Oct 2019 → 31 Oct 2023Funding: FWO fellowships
- A roadmap to the safe introduction of hESC in the clinic: the case of genetic mosaicism in hESC-derived retinal cellsFrom1 Jan 2019 → 31 Dec 2022Funding: FWO fellowships
- FWO Hercules MZW: Light sheet fluorescence microscopy in life sciences and medical researchFrom1 May 2018 → 30 Apr 2022Funding: FWO Medium Size Research Infrastructure
- The origins of mitochondrial DNA mosaicism in early human developmentFrom1 Jan 2018 → 31 Dec 2018Funding: FWO research grant KAN
- The identification of copy number variations that impede differentiation of human pluripotent stem cells.From1 Jan 2018 → 31 Dec 2018Funding: FWO research grant KAN
- The search for the origin of chromosomal abnormalities in human preimplantation embryosFrom1 Jan 2018 → 31 Dec 2021Funding: FWO research project (including WEAVE projects)
Publications
1 - 10 of 65
- Children born after assisted reproduction more commonly carry a mitochondrial genotype associating with low birthweight(2024)
Authors: Claudia Spits, Joke Mertens, Florence Belva, Aafke PA van Montfoort, Marius Regin, Filippo Zambelli, Sara Seneca, Edouard Couvreu De Deckersberg, Maryse Bonduelle, Herman Tournaye, et al.
- Genetics of infertility: a paradigm shift for medically assisted reproduction(2023)
Authors: Willem Verpoest, Özlem Okutman, Annelore Van Der Kelen, Karen Sermon, Stéphane Viville
Pages: 2289-2295 - Lineage segregation in human pre-implantation embryos is specified by YAP1 and TEAD1(2023)
Authors: Marius Regin, Wafaa Essahib, Andrej Demtschenko, Delphine Dewandre, Laurent David, Claudia Gerri, Kathy K Niakan, G Verheyen, H Tournaye, Johan Sterckx, et al.
Pages: 1484-1498 - A systematic review and evidence assessment of monogenic gene-disease relationships in human female infertility and differences in sex development(2023)
Authors: Annelore Van Der Kelen, Özlem Okutman, Elodie Javey, Münevver Serdarogullari, Charlotte Janssens, Manjusha S Ghosh, Bart J H Dequeker, Florence Perold, Claire Kastner, Emmanuelle Kieffer, et al.
Pages: 218-232 - #ESHREjc report(2023)
Authors: Sofia Makieva, Juan J Fraire-Zamora, Mina Mincheva, Julia Uraji, Zoya E Ali, Omar F Ammar, George Liperis, Munevver Serdarogullari, Enrica Bianchi, Jonathan Pettitt, et al.
Pages: 324-327 - Mitochondrial DNA variants segregate during human preimplantation development into genetically different cell lineages that are maintained postnatally(2022)
Authors: Joke Mertens, Marius Regin, Neelke De Munck, Edouard Couvreu De Deckersberg, Florence Belva, Karen Sermon, H Tournaye, Christophe Blockeel, Hilde Van De Velde, C Spits
Pages: 3629-3642 - Impaired catabolism of free oligosaccharides due to MAN2C1 variants causes a neurodevelopmental disorder(2022)
Authors: Nuno M. M. Maia, Sven Potelle, Hamide Yildirim, Sandrine Duvet, Shyam K. Akula, Celine Schulz, Elsa Wiame, Alexander Gheldof, Katherine O'kane, Abbe Lai, et al.
Pages: 345-360 - Myotonic dystrophy type 1 embryonic stem cells show decreased myogenic potential, increased CpG methylation at the DMPK locus and RNA mis-splicing(2022)
Authors: Silvie Franck, Edouard Couvreu De Deckersberg, Jodi L Bubenik, Christina Markouli, Lise Barbé, Joke Allemeersch, Pierre Hilven, Geoffrey Duqué, Maurice S Swanson, Alexander Gheldof, et al.
- ESHRE survey results and good practice recommendations on managing chromosomal mosaicism(2022)
Authors: Martine De Rycke, Antonio Capalbo, Edith Coonen, Giovanni Coticchio, Francesco Fiorentino, Veerle Goossens, Saria Mcheik, Carmen Rubio, Karen Sermon, Ioannis Sfontouris, et al.
- Sustained intrinsic WNT and BMP4 activation impairs hESC differentiation to definitive endoderm and drives the cells towards extra-embryonic mesoderm(2021)
Authors: Christina Markouli, Edouard Couvreu De Deckersberg, Dominika Alicja Dziedzicka, Marius Regin, Silvie Franck, Alexander Scott Keller, Alexander Gheldof, Mieke Geens, Karen Sermon, C Spits