Researcher
Julie De Backer
- Keywords:Aortic dissection, Marfan syndrome, Aortic Aneurysm, Cardiogenetics, congenital heart disease
- Disciplines:Vascular diseases, Cardiology, Cardiac and vascular medicine not elsewhere classified, Genetics
Affiliations
- Department of Internal Medicine and Pediatrics (Department)
Member
From1 Oct 2018 → Today - Department of Biomolecular Medicine (Department)
Member
From1 Oct 2018 → 30 Sep 2023 - Department of Internal medicine (Department)
Member
From1 Oct 2011 → 30 Sep 2018 - Department of Pediatrics and medical genetics (Department)
Member
From1 Oct 2001 → 30 Sep 2018
Projects
1 - 10 of 11
- Contribution of immune cells to vascular wall damage and dissection in Marfan syndromeFrom1 Jul 2024 → TodayFunding: Foreign foundations, funds with scientific view
- Advancing Personalized Care in Heritable Thoracic Aortic DiseasesFrom1 Jan 2024 → TodayFunding: BOF - projects
- Unraveling the mechanisms that drive cardiovascular manifestations in Marfan syndrome using mouse modelsFrom1 Nov 2023 → 30 Apr 2024Funding: BOF - doctoral mandates
- Paving the way to precision medicine in childhood-onset diseases: A lifespan perspective on accelerated aging using the epigenetic clockFrom1 Jan 2022 → TodayFunding: FWO research project (including WEAVE projects)
- A zebrafish platform for genetic and chemical screening to improve diagnosis, risk estimation and treatment of cardiovascular manifestations in Marfan syndrome.From1 Jan 2022 → TodayFunding: FWO research project (including WEAVE projects)
- An integrated translational platform to improve the management and outcome of rare heritable connective tissue diseaseFrom1 Jan 2021 → TodayFunding: BOF - projects
- Human stem cell-derived models to unveil mechanisms of impaired myocardial function in Marfan SyndromeFrom1 Oct 2019 → 30 Jul 2024Funding: BOF - projects
- Using advanced fluid dynamics modelling for cardiovascular phenotyping of zebrafish modelsFrom1 Oct 2018 → 30 Sep 2024Funding: BOF - Doctoral projects
- Using Zebrafish as a novel tool to Improve the Diagnosis and Outcome of Marfan SyndromeFrom1 Sep 2018 → 31 Aug 2020Funding: H2020-EU.1.3.- EXCELLEN SCIENCE - Marie Skłodowska-Curie actions
- Study of the genetic basis and molecular pathogenesis of cardiovascular manifestations in heritable thoracic aortic aneurysmsFrom1 Oct 2014 → 1 Nov 2019Funding: FWO fellowships, BOF - Other initiatives
Publications
1 - 10 of 219
- Three-dimensional co-culturing of stem cell-derived cardiomyocytes and cardiac fibroblasts reveals a role for both cell types in Marfan-related cardiomyopathy(2024)
Authors: Jeffrey Aalders, Laurens Léger, Louis Van der Meeren, Sanjay Sinha, Andre Skirtach, Julie De Backer, Jolanda van Hengel
Pages: 14 - 24 - Perinatal outcomes after in-utero exposure to beta-blockers in women with heart disease : data from the ESC EORP registry of pregnancy and cardiac disease (ROPAC)(2024)
Authors: Karishma P. Ramlakhan, Jolien W. Roos-Hesselink, Thomas Basso, Jaimi Greenslade, Robert B. Flint, Eric V. Krieger, Avraham Shotan, Werner Budts, Julie De Backer, Roger Hall, et al.
- Surveillance of adults with congenital heart disease : current guidelines and actual clinical practice(2024)
Authors: Jolien W. Roos-Hesselink, Chiara Pelosi, Margarita Brida, Julie De Backer, Sabine Ernst, Werner Budts, Helmut Baumgartner, Erwin Oechslin, Daniel Tobler, Adrienne H. Kovacs, et al.
- Bicuspid aortic valve disease with early-onset complications : characteristics and aortic outcomes(2024)
Authors: Maximilian A. Selbst, Colin R. Ward, Megan L. Svetgoff, Hector I. Michelena, Anna Sabate-Rotes, Julie De Backer, Laura Muiño Mosquera, Anji T. Yetman, Malenka M. Bissell, Maria Grazia Andreassi, et al.
Pages: 253 - 258 - Genetics of aortic disease(2024)Series: Biomechanics of living organs
Authors: Julie De Backer, Laura Muiño Mosquera, John A. Elefteriades, Christian Gasser, Stéphane Avril
Pages: 17 - 48 - TGFB3-related heritable thoracic aortic disease : results from the montalcino aortic consortium(2023)Volume: 81
Authors: Michelle Lim, Andrew Lai, Jonathan Schweber, Nikita Garg, Julie Fleischer, Julie De Backer, Laura Muiño Mosquera, Anji Yetman, Anthony David Caffarelli, Guillaume Jondeau, et al.
Pages: 2020 - 2020 - Unraveling the role of TGFβ signaling in thoracic aortic aneurysm and dissection using Fbn1 mutant mouse models(2023)
Authors: Violette Deleeuw, Eric Carlson, Marjolijn Renard, Keith D. Zientek, Phillip A. Wilmarth, Ashok P. Reddy, Elise C. Manalo, Sara F. Tufa, Douglas R. Keene, Margie Olbinado, et al.
Pages: 17 - 33 - Long-term follow-up of atrioventricular valve function in Fontan patients : effect of atrioventricular valve surgery(2023)
Authors: Thierry Bové, Eva Grootjans, Thomas Martens, Daniël De Wolf, Kristof Vandekerckhove, Joseph Panzer, Katya De Groote, Julie De Backer, Katrien Francois
- Application of an automated analysis framework for pulsed-wave Doppler cardiac ultrasound measurements to generate reference data in adult zebrafish(2023)
Authors: Matthias Van Impe, Lisa Caboor, Violette Deleeuw, Karo De Rycke, Michiel Vanhooydonck, Julie De Backer, Patrick Segers, Patrick Sips
Pages: R782 - R796 - Genetic testing in patients with congenital heart disease : you do no harm when using the right tools!(2023)
Authors: Julie De Backer, Laura Muiño Mosquera