Researcher
Juan Fraire
- Disciplines:Pharmacognosy and phytochemistry, Biomarker discovery and evaluation, Other pharmaceutical sciences, Toxicology and toxinology, Pharmacotherapy, Pharmacology, Pharmaceutical technology, Cell engineering, Clinical trials, Biopharmaceuticals
Affiliations
- Department of Pharmaceutics (Department)
Member
From14 Sep 2016 → 30 Sep 2023
Projects
1 - 1 of 1
- Light-triggered nanobombs for intracellular delivery of functional macromoleculesFrom1 Oct 2019 → 30 Sep 2022Funding: FWO junior postdoctoral fellowship
Publications
11 - 20 of 23
- Vapor nanobubble is the more reliable photothermal mechanism for inducing endosomal escape of siRNA without disturbing cell homeostasis(2020)
Authors: Juan Fraire, Gaëlle Houthaeve, Jing Liu, Laurens Raes, Lotte Vermeulen, Stephan Stremersch, Toon Brans, Gerardo Garcia-Diaz Barriga, Sarah De Keulenaer, Filip Van Nieuwerburgh, et al.
Pages: 262 - 275 - Intracellular labeling with extrinsic probes : delivery strategies and applications(2020)
Authors: Jing Liu, Juan Fraire, Stefaan De Smedt, Ranhua Xiong, Kevin Braeckmans
- Intracellular delivery of mRNA in adherent and suspension cells by vapor nanobubble photoporation(2020)
Authors: Laurens Raes, Stephan Stremersch, Juan Fraire, Toon Brans, Glenn Goetgeluk, Stijn De Munter, Lien Van Hoecke, Rein Verbeke, Jelter Van Hoeck, Ranhua Xiong, et al.
- Laser-induced vapor nanobubbles improve diffusion in biofilms of antimicrobial agents for wound care(2019)
Authors: Eline Teirlinck, Juan Carlos Fraire, Heleen Van Acker, Jasper Wille, Rosalie Swimberghe, Toon Brans, Ranhua Xiong, Maarten Meire, Roeland De Moor, Stefaan De Smedt, et al.
- Delivery of mixed-lineage kinase domain-like protein by vapor nanobubble photoporation induces necroptotic-like cell death in tumor cells(2019)
Authors: Lien Van Hoecke, Laurens Raes, Stephan Stremersch, Toon Brans, Juan Fraire, Ria Roelandt, Wim Declercq, Peter Vandenabeele, Koen Raemdonck, Kevin Braeckmans, et al.
- Gold nanoparticle-mediated photoporation enables delivery of macromolecules over a wide range of molecular weights in human CD4+ T cells(2019)
Authors: Laurens Raes, Clarissa Van Hecke, Julie Michiels, Stephan Stremersch, Juan Fraire, Toon Brans, Ranhua Xiong, Stefaan De Smedt, Linos Vandekerckhove, Koen Raemdonck, et al.
- Exploring light-sensitive nanocarriers for simultaneous triggered antibiotic release and disruption of biofilms upon generation of laser-induced vapor nanobubbles(2019)
Authors: Eline Teirlinck, Alexandre Barras, Jing Liu, Juan Fraire, Tatu Lajunen, Ranhua Xiong, Katrien Forier, Chengnan Li, Arto Urtti, Rabah Boukherroub, et al.
- Mechanistic profiling of the release kinetics of siRNA from lipidoid-polymer hybrid nanoparticles in vitro and in vivo after pulmonary administration(2019)
Authors: Kaushik Thanki, Delphine van Eetvelde, Antonia Geyer, Juan Fraire, Remi Hendrix, Hannelore Van Eygen, Emma Putteman, Haider Sami, Cristiane de Souza Carvalho-Wodarz, Henrik Franzyk, et al.
Pages: 82 - 93 - Photoablation of human vitreous opacities by light-induced vapor nanobubbles(2019)
Authors: Félix Sauvage, Juan Fraire, Katrien Remaut, J Sebag, Karen Peynshaert, Michael Harrington, Frans J Van de Velde, Ranhua Xiong, Marie-Jose Tassignon, Toon Brans, et al.
Pages: 8401 - 8416 - Improved label-free identification of individual exosome-like vesicles with Au@Ag nanoparticles as SERS substrate(2019)
Authors: Juan Fraire, Stephan Stremersch, Davinia Bouckaert, Tinne Monteyne, Thomas De Beer, Pieter Wuytens, Andre Skirtach, Koen Raemdonck, Kevin Braeckmans
Pages: 39424 - 39435
Patents
1 - 6 of 6
- Composition comprising at least one nanobomb suitable for altering a biological barrier (Inventor)
- Composition for treatment of vitreous disease or disorder (Inventor)
- Method and system for characterizing extracellular vesicles (Inventor)
- Composition comprising at least one nanobomb suitable for altering a biological barrier (Inventor)
- Composition for treatment of vitreous disease or disorder (Inventor)
- Method and system for characterizing extracellular vesicles (Inventor)