Researcher
Joost Schymkowitz
- Disciplines (Flanders Institute for Biotechnology):Analysis of next-generation sequence data, Cell death, Behavioural neuroscience
- Disciplines (KU Leuven):Proteins, Bioinformatics of disease, Structural bioinformatics and computational proteomics, Synthetic biology, Proteomics
- See also: Joost Schymkowitz (Flanders Institute for Biotechnology)
Affiliations
- Switch Lab (Research group)
Responsible
From1 Jan 2017 → Today - Switch Laboratory (VIB-KU Leuven) (Division)
Member
From1 Jan 2011 → Today - Department of Cellular and Molecular Medicine (Department)
Member
From15 Sep 2010 → 31 Dec 2010
Infrastructure
1 - 1 of 1
- When size matters: a platform to study molecular interactions and multimerisation (Consortium coordinator)
Projects
41 - 50 of 54
- The role of aggregation gatekeepers in proteostasis.From10 Dec 2014 → 23 Jun 2020Funding: IWT personal funding - strategic basic research grants
- Evaluation of p53 aggregation as a drug target in oncology.From1 Nov 2014 → 31 Oct 2018Funding: SBO (Strategic basic research)
- Adapting targeted protein aggregation for detection.From1 Oct 2014 → 30 Sep 2018Funding: IOF - Industrial Research Fund
- Development of Pept-Ins for in vivo imaging.From1 Sep 2014 → 20 Dec 2018Funding: IWT personal funding - strategic basic research grants
- Identifying novel aggregation-associated disease mutants.From1 Jan 2014 → 31 Dec 2014Funding: BOF - Other initiatives
- Triggers and interactions of protein aggregatesFrom1 Oct 2013 → 30 Sep 2023Funding: BOF - ZAP BOF mandates
- The function and interactoome of protein aggregatesFrom1 Jan 2013 → 31 Dec 2016Funding: FWO research project (including WEAVE projects)
- Aggregation as a mechanism for p53 oncogenic transformation: clinical relevance and new tools for its studyFrom1 Oct 2012 → 2 Oct 2017Funding: BOF - Doctoral projects
- Infrastructure enabling correlative light and electron microscopy for the Life Sciences.From28 Jun 2012 → 27 Dec 2018Funding: Hercules - Small and Medium size research infrastructure
- The Possible Role of the Staphylococcus epidermidis LPxTG Surface Protein SesC in Biofilm Formation and its use as a potentional vaccine targetFrom18 Apr 2012 → 18 May 2017Funding: Own budget, for example: patrimony, inscription fees, gifts
Publications
1 - 10 of 159
- Integrating physics in deep learning algorithms: a force field as a PyTorch module.(2024)
Authors: Gabriele Orlando, Joost Schymkowitz, Frederic Rousseau
Pages: btae160 - Local structural preferences in shaping tau amyloid polymorphism(2024)
Authors: Grigoria Tsaka, Rodrigo Gallardo, Dietmar Thal, Frederic Rousseau, Joost Schymkowitz
- N-glycosylation as a eukaryotic protective mechanism against protein aggregation.(2024)
Authors: Bert Houben, Matthias De Vleeschouwer, Matthew Wilson, Gert Matthijs, Joost Schymkowitz, Frederic Rousseau
Pages: eadk8173 - Modulation of hen egg white protein techno-functionality by amyloid formation(2024)
Authors: Anja Vananroye, Paula Moldenaers, Joost Schymkowitz, Frederic Rousseau, Jan Delcour
- LRRC37B is a human modifier of voltage-gated sodium channels and axon excitability in cortical neurons(2023)
Authors: Sofie Beckers, Katerina Konstantoulea, Maarten Dewilde, Frederic Rousseau, Joost Schymkowitz, Tom Theys, Joris de Wit, Pierre Vanderhaeghen
- Mechanisms and pathology of protein misfolding and aggregation(2023)
Authors: Nikolaos Louros, Joost Schymkowitz, Frederic Rousseau
Pages: 912 - 933 - Improved coalescence and creaming stability of structured oil-in-water emulsions and emulsion gels containing ovalbumin amyloid-like fibrils produced by heat and enzymatic treatments(2023)
Authors: Frederic Rousseau, Joost Schymkowitz, Jan Delcour
- TDP‑43 pathology is associated with increased tau burdens and seeding(2023)
Authors: Sandra Oliveira Tomé, Grigoria Tsaka, Klara Gawor, Philip Van Damme, Ludo Van Den Bosch, Rik Vandenberghe, Frederic Rousseau, Joost Schymkowitz, Dietmar Thal
- Exploiting the aggregation propensity of beta-lactamases to design inhibitors that induce enzyme misfolding(2023)
Authors: Laleh Khodaparast, Ladan Khodaparast, Emiel Michiels, Rodrigo Gallardo, Bert Houben, Matthias De Vleeschouwer, Frederic Rousseau, Joost Schymkowitz
- Amyloid-like p53 as prognostic biomarker in serous ovarian cancer-a study of the OVCAD consortium(2023)
Authors: Ignace Vergote, Toon Van Gorp, Frederic Rousseau, Joost Schymkowitz
Pages: 2473 - 2484
Patents
1 - 10 of 10
- Molecules targeting ras protein (Inventor)
- Molecules targeting proteins (Inventor)
- Molecules targeting mutant ras protein (Inventor)
- Beta-lactamase inhibitors (Inventor)
- Carbon dioxide generation (Inventor)
- Molecules targeting mutant ras protein (Inventor)
- Means and methods for the prediction of amyloid core sequences (Inventor)
- Molecules targeting proteins (Inventor)
- Molecules targeting ras protein (Inventor)
- Carbon dioxide generation (Inventor)