Researcher
Joost Schymkowitz
- Disciplines (Flanders Institute for Biotechnology):Analysis of next-generation sequence data, Cell death, Behavioural neuroscience
- Disciplines (KU Leuven):Proteins, Bioinformatics of disease, Structural bioinformatics and computational proteomics, Synthetic biology, Proteomics
- See also: Joost Schymkowitz (Flanders Institute for Biotechnology)
Affiliations
- Switch Lab (Research group)
Responsible
From1 Jan 2017 → Today - Switch Laboratory (VIB-KU Leuven) (Division)
Member
From1 Jan 2011 → Today - Department of Cellular and Molecular Medicine (Department)
Member
From15 Sep 2010 → 31 Dec 2010
Infrastructure
1 - 1 of 1
- When size matters: a platform to study molecular interactions and multimerisation (Consortium coordinator)
Projects
1 - 10 of 54
- The Hidden Biology of Inclusion BodiesFrom1 Jan 2024 → TodayFunding: FWO research project (including WEAVE projects)
- New molecular tools for diagnostic and treatment of systemic amyloidosisFrom2 Oct 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Structural and morphological studies of heterotypic amyloid fibrilsFrom1 Oct 2023 → TodayFunding: FWO junior postdoctoral fellowship
- Heterotypic aggregation of Aβ42 with disease-relevant proteins in Alzheimer’s diseaseFrom1 Oct 2023 → TodayFunding: FWO junior postdoctoral fellowship
- Cotranslational protein folding and aggregationFrom4 Sep 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Investigation of Heterotypic Interactions of TDP-43 Aggregation in NeurodegenerationFrom11 Apr 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- When size matters: a platform to study molecular interactions and multimerisationFrom1 May 2022 → TodayFunding: FWO Medium Size Research Infrastructure
- Characterization of novel antibiotics against bacterial protein secretion.From1 Apr 2022 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Convergence of tau and TDP-43 in Alzheimer's: towards a multitarget diagnosisFrom1 Dec 2021 → 31 Oct 2022Funding: BOF - postdoctoral mandates
- Rational design of biologics for therapeutic development (FoldCo)From19 Oct 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
Publications
71 - 80 of 159
- Thermodynamic and Evolutionary Coupling between the Native and Amyloid State of Globular Proteins(2020)
Authors: Rodrigo Gallardo, Rob van der Kant, Nikolaos Louros, Emiel Michiels, Bert Houben, Chris Ulens, Frederic Rousseau, Joost Schymkowitz
- Nanomaterials to avoid and destroy protein aggregates(2020)
Authors: Joost Schymkowitz, Frederic Rousseau, Bela Z Schmidt
- Preparation of Amorphous Solid Dispersions by Cryomilling: Chemical and Physical Concerns Related to Active Pharmaceutical Ingredients and Carriers(2020)
Authors: Timothy Pas, Emiel Michiels, Frederic Rousseau, Joost Schymkowitz, Robin Koekoekx, Christian Clasen, Guy Van den Mooter
Pages: 1001 - 1013 - Entropic Bristles Tune the Seeding Efficiency of Prion-Nucleating Fragments(2020)
Authors: Emiel Michiels, Rodrigo Gallardo, Nikolaos Louros, Joost Schymkowitz, Frederic Rousseau
Pages: 2834 - + - Protein Homeostasis Database: protein quality control in E.coli(2020)
Authors: Reshmi Ramakrishnan, Bert Houben, Joost Schymkowitz, Frederic Rousseau
Pages: 948 - 949 - WALTZ-DB 2.0: an updated database containing structural information of experimentally determined amyloid-forming peptides(2020)
Authors: Nikolaos Louros, Katerina Konstantoulea, Matthias De Vleeschouwer, Joost Schymkowitz, Frederic Rousseau
Pages: D389 - D393 - Large expert-curated database for benchmarking document similarity detection in biomedical literature search(2019)
Authors: Christopher McCrum, Mieke Deschodt, Koenraad Devriendt, Johan Joubert, Joost Schymkowitz
- Differential proteostatic regulation of insoluble and abundant proteins(2019)
Authors: Reshmi Ramakrishnan, Bert Houben, Frederic Rousseau, Joost Schymkowitz
Pages: 4098 - 4107 - Exposure of a cryptic Hsp70 binding site determines the cytotoxicity of the ALS-associated SOD1-mutant A4V(2019)
Authors: Filip Claes, Nikolaos Louros, Emiel Michiels, Rob van der Kant, Bert Houben, Wim Robberecht, Frederic Rousseau, Joost Schymkowitz
Pages: 443 - 457 - Assessing computational predictions of the phenotypic effect of cystathionine-beta-synthase variants(2019)
Authors: Frederic Rousseau, Joost Schymkowitz
Pages: 1530 - 1545
Patents
1 - 10 of 10
- Molecules targeting ras protein (Inventor)
- Molecules targeting proteins (Inventor)
- Molecules targeting mutant ras protein (Inventor)
- Beta-lactamase inhibitors (Inventor)
- Carbon dioxide generation (Inventor)
- Molecules targeting mutant ras protein (Inventor)
- Means and methods for the prediction of amyloid core sequences (Inventor)
- Molecules targeting proteins (Inventor)
- Molecules targeting ras protein (Inventor)
- Carbon dioxide generation (Inventor)