Researcher
Jonathan Baets
- Research Expertise:Neurogenetics, molecular genetics, neuropathology, clinical neurology, clinical neurophysiology
- Keywords:NEUROPATHOLOGY, NEURO MUSCULAR DISEASES, PATHOMECHANISM, HEREDITARY NEUROPATHIES, GENETIC DISEASE, Medicine
- Disciplines:Neurosciences, Genetics, Clinical genetics and molecular diagnostics, Neurological and neuromuscular diseases, Neurophysiology, Histology
- Research techniques:molecular genetics, histopathology, clinical neurophysiology
- Users of research expertise:neurologists, neuroscientists, geneticists
Affiliations
- Translational Neurosciences (TNW) (Research group)
Member
From1 Jan 2019 → Today - Neurogenetics Group (Research group)
Member
From1 Jan 2015 → 31 Dec 2018 - Neurogenetics Group (Research group)
Member
From1 Oct 2003 → 31 Dec 2014
Projects
1 - 10 of 13
- Impact of α-spectrin mutations on the cytoskeleton and organelle organization in neurodegeneration (SpecDroHuman).From1 Sep 2023 → TodayFunding: HORIZON.1.2 - Marie Skłodowska-Curie-actions (MSCA)
- Dissecting the role of the KDM5A overactivity in the pathophysiology of sporadic Inclusion Body myositis : from the deep proteome towards disease models and novel therapies.From27 Apr 2023 → TodayFunding: Foundations, funds and other with scientific goal
- Study of SPTAN1 pathomechanisms: the spectrin complex as a central hub in rare neurological and neuromuscular diseases.From1 Jan 2023 → TodayFunding: FWO research project
- Agreement Born-Bunge Institute and University of Antwerp, 2023-2027.From1 Jan 2023 → TodayFunding: Fund Recuperation Fiscal Exemption
- Validation and characterization of SPTAN1 mutations as a novel cause for hereditary cerebellar ataxia.From1 Apr 2021 → 31 Mar 2022Funding: BOF - projects
- Unraveling neuromuscular spectrinopathies through SPTAN1 genotype-phenotype correlationsFrom2 Feb 2021 → 31 Dec 2021Funding: Foundations, funds and other with scientific goal
- IMARK. Network for image-based biomarker discovery and evaluationFrom1 Jan 2021 → TodayFunding: IOF - mandates
- Multidimensional analysis of the nervous system in health and disease (µNeuro).From1 Jan 2020 → TodayFunding: BOF - research organisations, Fund Recuperation Fiscal Exemption
- Primary muscle degeneration in sporadic Inclusion-Body Myositis: combining deep-proteome data in patient muscle tissue with novel cellular models to pinpoint key mechanisms driving inflammation and aberrant protein expression.From1 Jan 2019 → 31 Dec 2021Funding: FWO research grant KAN
- La myosite à inclusions, une maladie inflammatoire dégénératif : une approche protéomique afin d'identifier les mécanismes perturbant l'homéostasie protéinique.From1 Jan 2018 → 31 Dec 2018Funding: Foundations, funds and other with scientific goal
Publications
41 - 50 of 79
- Multisystem proteinopathy due to a homozygous p.Arg159His VCP mutation: A tale of the unexpected(2020)
Authors: Willem De Ridder, Abdelkrim Azmi, Christoph S. Clemen, Ludwig Eichinger, Andreas Hofmann, Rolf Schroeder, Katherine Johnson, Ana Topf, Volker Straub, Peter De Jonghe, et al.
Pages: E785 - E796 - Tackling etiologically unsolved progressive muscle disorders(2020)
Authors: Willem De Ridder, Jonathan Baets, Peter De Jonghe
Number of pages: 199 - Malignant hyperthermia related DNA analysis (RYR1 gene) in Belgian families(2019)
Authors: Luc Heytens, M. Dos Santos Silva, J. De Puydt, K. Heytens, Willem De Ridder, Jonathan Baets, Geert Mortier
Pages: 197 - 205 - Pathogenic variants in the AFG3L2 proteolytic domain cause SCA28 through haploinsufficiency and proteostatic stress-driven OMA1 activation(2019)
Authors: Susanna Tulli, Andrea Del Bondio, Valentina Baderna, Davide Mazza, Franca Codazzi, Tyler Mark Pierson, Alessandro Ambrosi, Dagmar Nolte, Cyril Goizet, Camilo Toro, et al.
Pages: 499 - 511 - CMT disease severity correlates with mutation-induced open conformation of histidyl-tRNA synthetase, not aminoacylation loss, in patient cells(2019)
Authors: David Blocquel, Litao Sun, Zaneta Matuszekc, Sheng Li, Thomas Weber, Bernhard Kuhle, Grace Kooi, Na Wei, Jonathan Baets, Tao Pan, et al.
Pages: 19440 - 19448 - Functional characterization of GYG1 variants in two patients with myopathy and glycogenin-1 deficiency(2019)
Authors: Carola Hedberg-Oldfors, Willem De Ridder, Ognian Kalev, Klaus Boeck, Kittichate Visuttijai, Georg Caravias, Ana Toepf, Volker Straub, Jonathan Baets, Anders Oldfors
Pages: 951 - 960 - Extending the clinical and mutational spectrum of TRIM32-related myopathies in a non-Hutterite population(2019)
Authors: Katherine Johnson, Willem De Ridder, Ana Töpf, Marta Bertoli, Lauren Phillips, Peter De Jonghe, Jonathan Baets, Tine Deconinck, Vidosava Rakocevic Stojanovic, Stojan Peric, et al.
Pages: 490 - + - Safety and efficacy of intravenous bimagrumab in inclusion body myositis (RESILIENT): a randomised, double-blind, placebo-controlled phase 2b trial(2019)
Authors: Michael G. Hanna, Umesh A. Badrising, Olivier Benveniste, Thomas E. Lloyd, Merrilee Needham, Hector Chinoy, Masashi Aoki, Pedro M. Machado, Christina Liang, Katrina A. Reardon, et al.
Pages: 834 - 844 - NEK1 genetic variability in a Belgian cohort of ALS and ALS-FTD patients(2018)
Authors: Hung Nguyen Phuoc, Sara Van Mossevelde, Lubina Dillen, Jan L. De Bleecker, Matthieu Moisse, Philip Van Damme, Christine Van Broeckhoven, Julie van der Zee, Sebastiaan Engelborghs, Roeland Crois, et al.
- 221st ENMC International Workshop(2017)
Authors: Mary M. Reilly, Davide Pareyson, Joshua Burns, Matilde Laurá, Michael E. Shy, Dishan Singh, Jonathan Baets, et al.
Pages: 1138 - 1142