Researcher
Jonas Demeulemeester
- Disciplines (Flanders Institute for Biotechnology):Analysis of next-generation sequence data, Cell death, Cancer biology, Behavioural neuroscience
- Disciplines (KU Leuven):Artificial intelligence, Genetics, Bioinformatics and computational biology, Oncology, Medical systems biology
Affiliations
- Laboratory of Integrative Cancer Genomics (VIB-KU Leuven) (Division)
Responsible
From1 Jul 2022 → Today - Laboratory of Integrative Cancer Genomics (VIB-KU Leuven) (Division)
Member
From1 Aug 2022 → Today - Department of Oncology (Department)
Member
From1 Jul 2022 → 31 Jul 2022 - Demeulemeester lab (Research group)
Responsible
From1 Apr 2022 → Today - Aerts Lab (Research group)
Responsible
From1 Apr 2022 → 30 Jun 2022 - Aerts Lab (Research group)
Member
From1 Oct 2020 → 31 Mar 2022 - Laboratory of Reproductive Genomics (Division)
Member
From1 Oct 2015 → 30 Jun 2022 - Molecular Virology and Gene Therapy (Division)
Member
From1 Oct 2009 → 31 Jul 2015 - Biochemistry, Molecular and Structural Biology (Division)
Member
From13 Aug 2007 → 7 Sep 2007
Projects
1 - 7 of 7
- Machine Learning for Single-Molecule and Single-cell Multiomics to Bridge Genotype and Phenotype.From17 Sep 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- SymBioSys: Computationally mapping genomic heterogeneity from long read sequencing dataFrom1 Oct 2022 → TodayFunding: BOF - projects
- Single-molecule multi-omics to study tumour heterogeneity and evolutionFrom1 Sep 2022 → TodayFunding: Foundations, funds and other with scientific goal
- Integration of long read genome sequencing and single-cell multi-omics to identify genetic variation underlying Parkinson’s diseaseFrom1 Sep 2022 → TodayFunding: BOF - doctoral mandates
- Charting non-small cell lung cancer evolution and heterogeneity through multi-omics analysis and deconvolutionFrom1 Oct 2020 → 1 Jul 2022Funding: FWO senior postdoctoral fellowship
- Deconvolution of bulk tumour transcriptome and DNA methylation data to reveal underlying cell populations.From1 Oct 2015 → 30 Sep 2020Funding: FWO fellowships
- Development of a novel antiviral strategy directed against the nuclear import of HIV.From1 Oct 2009 → 13 Feb 2015Funding: FWO fellowships
Publications
31 - 40 of 87
- Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition(2020)
Authors: Jonas Demeulemeester
Pages: 306 - + - Butler enables rapid cloud-based analysis of thousands of human genomes(2020)
Authors: Jonas Demeulemeester
Pages: 288 - + - The evolutionary history of 2,658 cancers(2020)
Authors: Jonas Demeulemeester
Pages: 122 - + - Neoantigen-directed immune escape in lung cancer evolution(2019)
Authors: Jonas Demeulemeester, Peter Van Loo
Pages: 479 - + - Pan-cancer analysis of homozygous deletions in primary tumours uncovers rare tumour suppressors (vol 8, 1221, 2017)(2019)
Authors: Jiqiu Cheng, Jonas Demeulemeester, David C Wedge, Hans Kristian M Vollan, Jason J Pitt, Hege G Russnes, Bina P Pandey, Gro Nilsen, Silje Nord, Graham R Bignell, et al.
- Pan-cancer analysis of homozygous deletions in primary tumours uncovers rare tumour suppressors (vol 8, 1221, 2017)(2018)
Authors: Jiqiu Cheng, Jonas Demeulemeester, David C Wedge, Hans Kristian M Vollan, Jason J Pitt, Hege G Russnes, Bina P Pandey, Gro Nilsen, Silje Nord, Graham R Bignell, et al.
- Affinity switching of the LEDGF/p75 IBD interactome is governed by kinase-dependent phosphorylation(2018)
Authors: Jan De Rijck, Jonas Demeulemeester, Siska Van Belle, Frauke Christ, Zeger Debyser
Pages: E7053 - E7062 - Recurrent rearrangements of FOS and FOSB define osteoblastoma(2018)
Authors: Annelien Verfaillie, Jonas Demeulemeester, Peter Van Loo
- Inhibitors of the Integrase–Transportin-SR2 interaction block HIV nuclear import(2018)
Authors: Jonas Demeulemeester, Jolien Blokken, Stéphanie De Houwer, Lieve Dirix, Arnaud Marchand, Patrick Chaltin, Frauke Christ, Zeger Debyser
- LEDGF/p75 is dispensable for hematopoiesis but essential for MLL-rearranged leukemogenesis(2017)
Authors: Sara Elashkar, Jonas Demeulemeester, Frauke Christ, Siska Van Belle, Nancy Boeckx, Zeger Debyser, Jan De Rijck
Pages: 95 - 107