Researcher
Jonas Demeulemeester
- Disciplines (Flanders Institute for Biotechnology):Analysis of next-generation sequence data, Cell death, Cancer biology, Behavioural neuroscience
- Disciplines (KU Leuven):Artificial intelligence, Genetics, Bioinformatics and computational biology, Oncology, Medical systems biology
Affiliations
- Laboratory of Integrative Cancer Genomics (VIB-KU Leuven) (Division)
Responsible
From1 Jul 2022 → Today - Laboratory of Integrative Cancer Genomics (VIB-KU Leuven) (Division)
Member
From1 Aug 2022 → Today - Department of Oncology (Department)
Member
From1 Jul 2022 → 31 Jul 2022 - Demeulemeester lab (Research group)
Responsible
From1 Apr 2022 → Today - Aerts Lab (Research group)
Responsible
From1 Apr 2022 → 30 Jun 2022 - Aerts Lab (Research group)
Member
From1 Oct 2020 → 31 Mar 2022 - Laboratory of Reproductive Genomics (Division)
Member
From1 Oct 2015 → 30 Jun 2022 - Molecular Virology and Gene Therapy (Division)
Member
From1 Oct 2009 → 31 Jul 2015 - Biochemistry, Molecular and Structural Biology (Division)
Member
From13 Aug 2007 → 7 Sep 2007
Projects
1 - 7 of 7
- Machine Learning for Single-Molecule and Single-cell Multiomics to Bridge Genotype and Phenotype.From17 Sep 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- SymBioSys: Computationally mapping genomic heterogeneity from long read sequencing dataFrom1 Oct 2022 → TodayFunding: BOF - projects
- Single-molecule multi-omics to study tumour heterogeneity and evolutionFrom1 Sep 2022 → TodayFunding: Foundations, funds and other with scientific goal
- Integration of long read genome sequencing and single-cell multi-omics to identify genetic variation underlying Parkinson’s diseaseFrom1 Sep 2022 → TodayFunding: BOF - doctoral mandates
- Charting non-small cell lung cancer evolution and heterogeneity through multi-omics analysis and deconvolutionFrom1 Oct 2020 → 1 Jul 2022Funding: FWO senior postdoctoral fellowship
- Deconvolution of bulk tumour transcriptome and DNA methylation data to reveal underlying cell populations.From1 Oct 2015 → 30 Sep 2020Funding: FWO fellowships
- Development of a novel antiviral strategy directed against the nuclear import of HIV.From1 Oct 2009 → 13 Feb 2015Funding: FWO fellowships
Publications
21 - 30 of 87
- A pan-cancer landscape of somatic mutations in non-unique regions of the human genome(2021)
Authors: Jonas Demeulemeester, Annelien Verfaillie
Pages: 1589 - + - A ubiquitous disordered protein interaction module orchestrates transcription elongation(2021)
Authors: Jonas Demeulemeester, Zeger Debyser
Pages: 1113 - + - Aberrant integration of Hepatitis B virus DNA promotes major restructuring of human hepatocellular carcinoma genome architecture(2021)
Authors: Jonas Demeulemeester
- Evolutionary predictability of genetic versus nongenetic resistance to anticancer drugs in melanoma(2021)
Authors: Michael Dewaele, Panagiotis Karras, Nina Van Raemdonck, Dennis Pedri, Jonas Demeulemeester, Sara Vander Borght, Francesca Bosisio, Joost van den Oord, Isabelle Vanden Bempt, Diether Lambrechts, et al.
Pages: 1135 - + - Interpretation of allele-specific chromatin accessibility using cell state-aware deep learning(2021)
Authors: Ibrahim Ihsan Taskiran, Jonas Demeulemeester, David Mauduit, Valerie Christiaens, Jasper Wouters, Stein Aerts
- Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes(2021)
Authors: Jonas Demeulemeester
Pages: 2239 - + - Transcriptional profiling of STAT1 gain-of-function reveals common and mutation-specific fingerprints(2021)
Authors: Simone Giovannozzi, Jonas Demeulemeester, Rik Schrijvers, Rik Gijsbers
- Drivers underpinning the malignant transformation of giant cell tumour of bone(2020)
Authors: Jonas Demeulemeester
Pages: 433 - 440 - Pervasive chromosomal instability and karyotype order in tumour evolution(2020)
Authors: Jonas Demeulemeester
Pages: 126 - + - Integrated analysis of gene expression and chromosomal aberrations to determine the global patterns of DNA methylation heterogeneity in the TRACERx lung study(2020)
Authors: F Gimeno-Valiente, K Chen, EL Cadieux, TBK Watkins, O Chervova, P Dhami, H Vaikkinen, A Feber, Jonas Demeulemeester, M Tanic, et al.
Pages: S799 - S799