Researcher
Jo Vandesompele
- Keywords:non-coding RNA, RNA, Applied bioinformatics, DNA, cancer, liquid biopsy, DNA and RNA sequencing, PCR
- Disciplines:Cancer diagnosis, Cancer prevention, Cancer epidemiology, Cancer biology, Cancer therapy, Analysis of next-generation sequence data, Bioinformatics of disease, Bioinformatics data integration and network biology, Data visualisation and high-throughput image analysis, Ontologies, data curation and text mining, Development of bioinformatics software, tools and databases, Clinical genetics and molecular diagnostics, Oncology not elsewhere classified, Medical epigenomics, Medical metagenomics, Medical genomics, Single-cell data analysis, Bioinformatics and computational biology not elsewhere classified, Structural bioinformatics and computational proteomics
Affiliations
- Department of Biomolecular Medicine (Department)
Member
From1 Oct 2018 → Today - Department of Pediatrics and medical genetics (Department)
Member
From1 Oct 1997 → 30 Sep 2018
Projects
1 - 10 of 32
- Development of methods for the quantification of nucleic acids in functional genomics in cancerFrom16 Sep 2023 → 15 Jan 2024Funding: BOF - doctoral mandates
- International thematic network - PrIOMICFrom1 Jan 2023 → TodayFunding: BOF - mobility
- 6-color digital PCR instrumentFrom15 Dec 2022 → TodayFunding: BOF - scientific equipment program
- Every cell counts! Transforming exercise science through single fiber transcriptome analysis in human skeletal muscleFrom1 Oct 2022 → TodayFunding: FWO junior postdoctoral fellowship
- Cell-free nucleic acid profiling in diffuse large B-cell lymphoma: a molecular guidance to precision medicineFrom1 Oct 2022 → 31 Oct 2022Funding: BOF - doctoral mandates
- Replication fork protector dependency factors: novel targets for combination treatment and immunomodulation in neuroblastoma (REINFORCE)From1 Jan 2022 → TodayFunding: BOF - projects
- Development of a laboratory toolbox to study human circular RNAsFrom1 Oct 2021 → TodayFunding: BOF - projects
- The biology of tumor-derived extracellular RNA in liquid biopsiesFrom1 Nov 2020 → TodayFunding: FWO junior postdoctoral fellowship
- Cancer-specific circulating RNAs as biomarkers for diagnosis and therapy response monitoringFrom1 Nov 2020 → TodayFunding: FWO fellowships
- Analyzing circulating bacterial extracellular vesicles in cancer patients to identify their composition and biomarker potential.From1 Nov 2020 → 31 Mar 2023Funding: FWO fellowships
Publications
1 - 10 of 120
- Nationwide quality assurance of high-throughput diagnostic molecular testing during the SARS-CoV-2 pandemic : role of the Belgian National Reference Centre(2024)
Authors: Reile Janssen, Lize Cuypers, Lies Laenen, Els Keyaerts, Kurt Beuselinck, Sunita Janssenswillen, Bram Slechten, Jannes Bode, Elke Wollants, Kristel Van Laethem, et al.
- HTSplotter : an end-to-end data processing, analysis and visualisation tool for chemical and genetic in vitro perturbation screening(2024)
Authors: Carolina de Carvalho Nunes, Jasper Anckaert, Fanny De Vloed, Jolien De Wyn, Kaat Durinck, Jo Vandesompele, Franki Speleman, Vanessa Vermeirssen
- Nucleic acid degradation as barrier to gene delivery : a guide to understand and overcome nuclease activity(2024)
Authors: Heyang Zhang, Jo Vandesompele, Kevin Braeckmans, Stefaan De Smedt, Katrien Remaut
Pages: 317 - 360 - Blocking abundant RNA transcripts by high-affinity oligonucleotides during transcriptome library preparation(2023)
Authors: Celine Everaert, Jasper Verwilt, Kimberly Verniers, Niels Vandamme, Alvaro Marcos Rubio, Jo Vandesompele, Pieter Mestdagh
- Performance evaluation of RNA purification kits and blood collection tubes in the Extracellular RNA Quality Control (exRNAQC) study(2023)
Authors: Anneleen Decock, Olivier De Wever, Celine Everaert, Hetty Helsmoortel, An Hendrix, Pieter Mestdagh, Annelien Morlion, Jo Vandesompele, Ruben Van Paemel, Francisco Avila Cobos, et al.
Number of pages: 1 - Performance evaluation of RNA purification kits and blood collection tubes in the Extracellular RNA Quality Control (exRNAQC) study(2023)
Authors: Anneleen Decock, Olivier De Wever, Celine Everaert, Hetty Helsmoortel, An Hendrix, Pieter Mestdagh, Annelien Morlion, Jo Vandesompele, Ruben Van Paemel, Francisco Avila Cobos, et al.
Number of pages: 1 - Large-scale benchmarking of circRNA detection tools reveals large differences in sensitivity but not in precision(2023)
Authors: Marieke Vromman, Jasper Anckaert, Stefania Bortoluzzi, Alessia Buratin, Chia-Ying Chen, Qinjie Chu, Trees-Juen Chuang, Roozbeh Dehghannasiri, Christoph Dieterich, Xin Dong, et al.
Pages: 1159 - 1169 - Exploring the cell-free total RNA transcriptome in diffuse large B-cell lymphoma and primary mediastinal B-cell lymphoma patients as biomarker source in blood plasma liquid biopsies(2023)
Authors: Philippe Decruyenaere, Edoardo Giuili, Kimberly Verniers, Jasper Anckaert, Katrien De Grove, Malaïka Van der Linden, Dries Deeren, Jo Van Dorpe, Fritz Offner, Jo Vandesompele
- Circular RNA detection pipelines yield divergent sets of circular RNAs(2023)
Authors: Marieke Vromman, Jo Vandesompele
Pages: 1135 - 1136 - Exploration of neuroblastoma xenograft models for tumor extracellular RNA profiling in murine blood plasma(2023)
Authors: Jill Deleu, Hanne Van Droogenbroeck, Jasper Anckaert, Anneleen Decock, Jilke De Wilde, Kaat Durinck, Liselot Mus, Justine Nuytens, Muhammad Rishfi, Kathleen Schoofs, et al.
Patents
1 - 6 of 6
- Inhibition of a lncRNA for treatment of melanoma (Inventor)
- Biomarkers for disease burden of neuroblastoma (Inventor)
- Usages of recombinant extracellular vesicles (Inventor)
- Biomarkers for disease burden of neuroblastoma (Inventor)
- Usages of recombinant extracellular vesicles (Inventor)
- Inhibition of a lncRNA for treatment of melanoma (Inventor)
Linked dataset
1 - 1 of 1