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Researcher
Johan Vande Voorde
- Disciplines:Microbiology, Systems biology, Laboratory medicine
Affiliations
- Laboratory of Virology and Chemotherapy (Rega Institute) (Division)
Member
From1 Jun 2008 → 16 Apr 2017 - Laboratory of Molecular Bacteriology (Rega Institute) (Division)
Member
From5 Nov 2007 → 31 May 2008
Projects
1 - 1 of 1
- The effect of Mycoplasma enzymes on the antiviral and anticancer activity of nucleoside analoguesFrom1 Jun 2008 → 2 Dec 2013Funding: IWT personal funding - strategic basic research grants
Publications
11 - 17 of 17
- Role of human hypoxanthine guanine phosphoribosyltransferase in activation of the antiviral agent T-705 (favipiravir)(2013)
Authors: Lieve Naesens, Johan Vande Voorde, Jan Balzarini
Pages: 615 - 629 - Characterization of pyrimidine nucleoside phosphorylase of Mycoplasma hyorhinis: implications for the clinical efficacy of nucleoside analogues(2012)
Authors: Johan Vande Voorde, Kristof Vrancken, Sandra Liekens, Jan Balzarini
Pages: 113 - 23 - Inhibition of pyrimidine and purine nucleoside phosphorylases by a 3,5-dichlorobenzoyl-substituted 2-deoxy-d-ribose-1-phosphate derivative(2012)
Authors: Johan Vande Voorde, Sandra Liekens, Jan Balzarini
Pages: 1358 - 63 - Phosphoramidate ProTides of the anticancer agent FUDR successfully deliver the preformed bioactive monophosphate in cells and confer advantage over the parent nucleoside(2011)
Authors: Johan Vande Voorde, Sandra Liekens, Jan Balzarini
Pages: 7247 - 7258 - The cytostatic activity of NUC-3073, a phosphoramidate prodrug of 5-fluoro-2'-deoxyuridine, is independent of activation by thymidine kinase and insensitive to degradation by phosphorolytic enzymes(2011)
Authors: Johan Vande Voorde, Sandra Liekens, Jan Balzarini
Pages: 441 - 52 - Synthesis and biological evaluation of unsaturated keto and exomethylene d-arabinopyranonucleoside analogs: Novel 5-fluorouracil analogs that target thymidylate synthase(2011)
Authors: Johan Vande Voorde, Sandra Liekens, Jan Balzarini
Pages: 993 - 1005 - Evidence for the presence of Legionella bacteriophages in environmental water samples
Authors: Johan Vande Voorde, Liesbeth Maes, Jozef Anné
Pages: 191 - 7