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Researcher
Johan Swinnen
- Disciplines:Oncology, Medical systems biology
Affiliations
- Laboratory of Lipid Metabolism and Cancer (Division)
Responsible
From1 Jan 2012 → Today - Laboratory of Lipid Metabolism and Cancer (Division)
Member
From1 Jan 2012 → Today - Clinical and Experimental Endocrinology (Division)
Member
From1 Jan 2003 → 31 Dec 2011 - Department of Development and Regeneration (Department)
Member
From1 Oct 2000 → 31 Dec 2002
Infrastructure
1 - 2 of 2
- An high-throughput automated small molecule screening platform (Consortium coordinator)
- Next Generation Magnetic Resonance Mass Spectrometry. (Consortium coordinator)
Projects
1 - 10 of 51
- Targeting lipid metabolism to overcome cancer therapy resistanceFrom1 Apr 2024 → TodayFunding: IOF - mandates
- Een uitgebreide pijplijn voor translationeel onderzoek en training die het lipidenmetabolisme benut om de behandeling van prostaatkanker te verbeteren en jonge onderzoekers op te leiden in de aanpak van complexe ziektenFrom1 Jan 2024 → TodayFunding: HORIZON.1.2 - Marie Skłodowska-Curie-actions (MSCA)
- A Comprehensive Translational Research and Training Pipeline Harnessing Lipid Metabolism to Improve Prostate Cancer Management and Educate Young Researchers in Tackling Complex DiseaseFrom1 Jan 2024 → TodayFunding: BOF - projects
- Chemical Imaging of Biological Systems by Mass Spectrometry Imaging-enhanced Coherent Raman Scattering MicroscopyFrom2 Oct 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- 4D-Lipidomics: a new standard in advanced lipidomics researchFrom1 Jan 2023 → TodayFunding: BOF - scientific equipment program
- LipoMacs: functional Lipidomics to unlock Macrophage-mediated therapyFrom1 Oct 2022 → TodayFunding: FWO Strategic Basic Research (SBO)
- Multimodal Coherent Raman Scattering /Fluorescence Lifetime Imaging Microscopy systemFrom2 Aug 2022 → TodayFunding: Other federal scientific institutions
- An high-throughput automated small molecule screening platform.From1 May 2022 → TodayFunding: FWO Large scale research infrastructure
- Aggressive salivary gland neoplasms: institutional-international collaborative evaluation of advances in clinical management and translational research into tumor biologyFrom11 Jan 2022 → 31 Dec 2023Funding: Own budget, for example: patrimony, inscription fees, gifts
- Inter-organelle communication through membrane contact sites in oncology and neurodegenerative diseases (InterAction)From1 Oct 2021 → TodayFunding: Fund Recuperation Fiscal Exemption, BOF - projects
Publications
101 - 110 of 133
- The effects of the clinically applicable chemotherapeutics on theimmunogenicity of melanoma cell death.(2015)
Authors: Patrizia Agostinis, Johan Swinnen
- Concurrent MEK and autophagy inhibition is required to restore cell death associated danger-signalling in Vemurafenib-resistant melanoma cells(2015)
Authors: Shaun Martin, Hannelore Maes, Abhishek Garg, Seyma Demirsoy, Johan Swinnen, Patrizia Agostinis
Pages: 290 - 304 - The novo lipogenesis as a target for anti-cancer therapy: an in vitrostudy on feasibility and underlying mechanisms(2014)
Authors: Veerle Daniëls, Johan Swinnen, Patrizia Agostinis
Number of pages: 140 - Cancer Cells Differentially Activate and Thrive on De Novo Lipid Synthesis Pathways in a Low-Lipid Environment(2014)
Authors: Veerle Daniëls, Johan Swinnen
- Lipogenesis and lipolysis: The pathways exploited by the cancer cells to acquire fatty acids(2013)
Authors: Johan Swinnen
Pages: 585 - 9 - A possible role for micro-RNA 141 down-regulation in sunitinib resistant metastatic clear cell renal cell carcinoma through induction of epithelial-to-mesenchymal transition and hypoxia resistance(2013)
Authors: Joost Berkers, Olivier Govaere, Benoit Beuselinck, Patrick Schöffski, Maarten Albersen, Joost van den Oord, Tania Roskams, Johan Swinnen, Steven Joniau, Hendrik Van Poppel, et al.
Pages: 1930 - 8 - Evaluation of androgen-induced effects on the uptake of [18F]FDG, [11C]choline and [11C]acetate in an androgen-sensitive and androgen-independent prostate cancer xenograft model(2013)
Authors: Johan Swinnen, Evelyne Lerut, Michel Koole, Luc Mortelmans, Felix Mottaghy
Pages: 31 - 31 - ATP Citrate Lyase Knockdown Induces Growth Arrest and Apoptosis through Different Cell- and Environment-Dependent Mechanisms(2012)
Authors: Johan Swinnen
Pages: 1925 - 1935 - ATP-citrate lyase: a key player in cancer metabolism(2012)
Authors: Johan Swinnen
Pages: 3709 - 3714 - De novo lipogenesis and membrane remodeling in cancer(2012)
Authors: Ali Talebi, Jonas Dehairs, Johan Swinnen
Pages: 49 - 53
Patents
1 - 5 of 5
- Screening methods for compounds modulating polyamine transport (Inventor)
- Combination treatment of arsenic oxide and antiandrogens (Inventor)
- Cancer phospholipidome (Inventor)
- CANCER PHOSPHOLIPIDOME (Inventor)
- PHOSPHOLIPID PROFILING OF CANCER (Inventor)