Researcher
Johan Swinnen
- Disciplines:Oncology, Medical systems biology
Affiliations
- Laboratory of Lipid Metabolism and Cancer (Division)
Responsible
From1 Jan 2012 → Today - Laboratory of Lipid Metabolism and Cancer (Division)
Member
From1 Jan 2012 → Today - Clinical and Experimental Endocrinology (Division)
Member
From1 Jan 2003 → 31 Dec 2011 - Department of Development and Regeneration (Department)
Member
From1 Oct 2000 → 31 Dec 2002
Infrastructure
1 - 2 of 2
- An high-throughput automated small molecule screening platform (Consortium coordinator)
- Next Generation Magnetic Resonance Mass Spectrometry. (Consortium coordinator)
Projects
1 - 10 of 51
- Targeting lipid metabolism to overcome cancer therapy resistanceFrom1 Apr 2024 → TodayFunding: IOF - mandates
- Een uitgebreide pijplijn voor translationeel onderzoek en training die het lipidenmetabolisme benut om de behandeling van prostaatkanker te verbeteren en jonge onderzoekers op te leiden in de aanpak van complexe ziektenFrom1 Jan 2024 → TodayFunding: HORIZON.1.2 - Marie Skłodowska-Curie-actions (MSCA)
- A Comprehensive Translational Research and Training Pipeline Harnessing Lipid Metabolism to Improve Prostate Cancer Management and Educate Young Researchers in Tackling Complex DiseaseFrom1 Jan 2024 → TodayFunding: BOF - projects
- Chemical Imaging of Biological Systems by Mass Spectrometry Imaging-enhanced Coherent Raman Scattering MicroscopyFrom2 Oct 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- 4D-Lipidomics: a new standard in advanced lipidomics researchFrom1 Jan 2023 → TodayFunding: BOF - scientific equipment program
- LipoMacs: functional Lipidomics to unlock Macrophage-mediated therapyFrom1 Oct 2022 → TodayFunding: FWO Strategic Basic Research (SBO)
- Multimodal Coherent Raman Scattering /Fluorescence Lifetime Imaging Microscopy systemFrom2 Aug 2022 → TodayFunding: Other federal scientific institutions
- An high-throughput automated small molecule screening platform.From1 May 2022 → TodayFunding: FWO Large scale research infrastructure
- Aggressive salivary gland neoplasms: institutional-international collaborative evaluation of advances in clinical management and translational research into tumor biologyFrom11 Jan 2022 → 31 Dec 2023Funding: Own budget, for example: patrimony, inscription fees, gifts
- Inter-organelle communication through membrane contact sites in oncology and neurodegenerative diseases (InterAction)From1 Oct 2021 → TodayFunding: Fund Recuperation Fiscal Exemption, BOF - projects
Publications
11 - 20 of 133
- Altered Functionality of Lipoprotein(a) Impacts on Angiogenesis in Diabetic Retinopathy(2023)
Authors: Jonas Dehairs, Johan Swinnen
- Pharmacological induction of membrane lipid poly-unsaturation sensitizes melanoma to ROS inducers and overcomes acquired resistance to targeted therapy(2023)
Authors: Ali Talebi, Vincent de Laat, Xander Spotbeen, Jonas Dehairs, Ginevra Doglioni, David Nittner, Tania Roskams, Patrizia Agostinis, Oliver Bechter, Veerle Boecxstaens, et al.
- Uncovering a novel role of peroxisomal β-oxidation in advanced, treatment-resistant prostate cancer(2023)
Authors: Jonas Dehairs, Johan Swinnen
- A palmitate-rich metastatic niche enables metastasis growth via p65 acetylation resulting in pro-metastatic NF-κB signaling(2023)
Authors: Ginevra Doglioni, Alex Cuadros, Xiaozheng Liu, dorien Broekaert, Sofie Demeyer, Xander Spotbeen, Margherita Demicco, François Richard, Tatjana Geukens, Maxim De Schepper, et al.
Pages: 344 - + - PERK recruits E-Syt1 at ER-mitochondria contacts for mitochondrial lipid transport and respiration(2023)
Authors: Maria Livia Sassano, Alex van Vliet, Chris Van den Haute, Johan Swinnen, Leen Moens, Kristina Casteels, Isabelle Meyts, Patrizia Agostinis
- AI-based MRI auto-segmentation of brain tumor in rodents, a multicenter study(2023)
Authors: Shuncong Wang, Johan Swinnen
- Junctional adhesion molecule-A is dispensable for myeloid cell recruitment and diversification in the tumor microenvironment(2022)
Authors: Isabelle Scheyltjens, Ali Talebi, Johan Swinnen
- NOVEL THERAPY FOR BRAIN METASTASIS(2022)
Authors: Shuncong Wang, Yicheng Ni, Guy Bormans, Johan Swinnen
- The ApoA-I mimetic peptide 5A enhances remyelination by promoting clearance and degradation of myelin debris(2022)
Authors: Jonas Dehairs, Johan Swinnen
- Cholesterol in macrophage-derived extracellular vesicles drives remyelination in the brain(2022)
Authors: Jonas Dehairs, Johan Swinnen
Pages: 1013 - 1014
Patents
1 - 5 of 5
- Screening methods for compounds modulating polyamine transport (Inventor)
- Combination treatment of arsenic oxide and antiandrogens (Inventor)
- Cancer phospholipidome (Inventor)
- CANCER PHOSPHOLIPIDOME (Inventor)
- PHOSPHOLIPID PROFILING OF CANCER (Inventor)