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Researcher
Johan Neyts
- Disciplines:Microbiology, Systems biology, Laboratory medicine
Affiliations
- Faculty of Medicine (Faculty)
Member
From1 Oct 2000 → 30 Sep 2002 - Laboratory of Virology and Chemotherapy (Rega Institute) (Division)
Member
From1 Oct 1999 → Today
Infrastructure
1 - 1 of 1
Projects
61 - 70 of 82
- Development of potent antivirals for the treatment and prophylaxis of norovirus infections.From1 Oct 2014 → 30 Sep 2015Funding: IOF - Industrial Research Fund
- The yellow fever vaccine at work: Mechanisms and platform for chronic hepatitis B and COVID-19 vaccinesFrom1 Sep 2014 → 15 Sep 2021Funding: Own budget, for example: patrimony, inscription fees, gifts
- Discovery, initial hit-optimization and mechanism of action of novel inhibitors of enterovirus.From1 Sep 2014 → 1 Jun 2018Funding: Own budget, for example: patrimony, inscription fees, gifts
- An automated platform for multiparameter data collection on live pathogens of higher or unknown biosafety risk.From26 Jun 2014 → 31 Dec 2018Funding: Hercules - Large scale research infrastructure
- Academia-Industry Research and Development Opportunities for Picornaviruses.From1 Jan 2014 → 31 Dec 2017Funding: Marie Curie - People
- Exploring molecular targets for inhibition of alpha- and enterovirus replicationFrom4 Nov 2013 → 11 May 2017Funding: Own budget, for example: patrimony, inscription fees, gifts
- Advanced studies towards knowledge on Lyssavirus Encephalitis Pathogenesis improving options for survival.From1 Nov 2013 → 31 Oct 2016Funding: General Activities (Annex IV)
- A novel, DNA-based, live-attenuated vaccine for the yellow fever virus and other medically important flaviviruses.From1 Oct 2013 → 30 Sep 2014Funding: IOF - Industrial Research Fund
- Protein-protein interactions as a potential target voor antiviral therapy: development of inhibitors of the HCV NS5A-PI4KIII- alfa interaction.From1 Jan 2013 → 15 Aug 2014Funding: IWT personal funding - strategic basic research grants
- The intimate link between hepatitis C virus and the host lipid metabolism as a potential target for inhibition of viral replication.From1 Oct 2012 → 30 Sep 2016Funding: FWO fellowships
Publications
1 - 10 of 621
- Mechanism of action of phthalazinone derivatives against rabies virus.(2024)
Authors: Dirk Jochmans, Johan Neyts
Pages: 105838 - Design, synthesis, and molecular modeling studies of novel 2-quinolone-1,2,3-triazole-α-aminophosphonates hybrids as dual antiviral and antibacterial agents.(2024)
Authors: Johan Neyts, Dirk Jochmans, Steven De Jonghe
Pages: 116235 - Beware of drug resistance: Let's not lose tecovirimat against mpox.(2024)
Authors: Johan Neyts, Laurens Liesenborghs
Pages: 276 - 278 - Molnupiravir inhibits human norovirus and rotavirus replication in 3D human intestinal enteroids.(2024)
Authors: Jana Van Dycke, Johan Neyts, Jelle Matthijnssens, Joana Duarte Da Rocha Pereira
Pages: 105839 - Lower respiratory tract single-cell RNA sequencing and neutrophil extracellular trap profiling of COVID-19-associated pulmonary aspergillosis: a single centre, retrospective, observational study.(2024)
Authors: Simon Feys, Sam Vanmassenhove, Bram Boeckx, Seppe Cambier, Yves Debaveye, Greet Hermans, Katrien Lagrou, Johan Neyts, Marijke Peetermans, Joana Duarte Da Rocha Pereira, et al.
Pages: e247 - e260 - Discovery of JNJ-1802, a First-in-Class Pan-Serotype Dengue Virus NS4B Inhibitor(2024)
Authors: Suzanne Kaptein, Johan Neyts
Pages: 4063 - 4082 - Integrating artificial intelligence-based epitope prediction in a SARS-CoV-2 antibody discovery pipeline: caution is warranted(2024)
Authors: Dirk Jochmans, Rana Abdelnabi, Birgit Weynand, Johan Neyts
- Studies of the human-to-human spread of respiratory pathogens.(2024)
Authors: Emmanuel Andre, Johan Neyts
- Genetic consequences of effective and suboptimal dosing with mutagenic drugs in a hamster model of SARS-CoV-2 infection(2024)
Authors: Rana Abdelnabi, Johan Neyts
- Design, synthesis, and lead optimization of piperazinyl-pyrimidine analogues as potent small molecules targeting the viral capping machinery of Chikungunya virus(2024)
Authors: Rana Abdelnabi, Johan Neyts, Leen Delang
Patents
1 - 10 of 10
- Corona virus binders (Inventor)
- Lassavirus vaccines (Inventor)
- Chimeric filovirus vaccines (Inventor)
- Chimeric zika-japanese encephalitis virus (Inventor)
- Chimeric yellow fever zika virus strain (Inventor)
- Viral replication inhibitors (Inventor)
- Treatment and prevention of dengue disease (Inventor)
- Coronavirus vaccines (Inventor)
- Design synthesis and methods of use of acyclic fleximer nucleoside analogues having anti-coronavirus activity (Inventor)
- Treatment and prevention of dengue disease (Inventor)