Researcher
Johan Grooten
- Disciplines:Immunology not elsewhere classified, Allergology, Adaptive immunology, Applied immunology, Autoimmunity, Immunogenetics, Transplantation immunology, Innate immunity, Vaccinology, Microbiology not elsewhere classified
Affiliations
- Department of Biomedical molecular biology (Department)
Responsible
From1 Oct 2010 → 30 Sep 2017 - Department of Biomedical molecular biology (Department)
Member
From1 Oct 2010 → 30 Sep 2017 - Department of Biomedical molecular biology (Department)
Member
From1 May 1996 → 30 Sep 2020 - Department of Plant Biotechnology and Bioinformatics (Department)
Member
From1 Jan 1993 → 30 Apr 1996
Projects
1 - 6 of 6
- Advancing novel and promising TB vaccine candidates from discovery to preclinical and early clinical developmentFrom1 Jan 2015 → 31 Dec 2018Funding: H2020 - Health, demographic change and wellbeing
- Targeting the modified innate functionality of the post-asthma alveolar macrophage for relieving Respiratory Syncytical Virus-induced astham exacerbation.From2 Jul 2013 → 31 May 2015Funding: Foundations, funds and other with scientific goal
- Increasing the efficiency of RNA-cancer vaccination by modulation of type-I-IFN activity, and interference with PD-LI / PD-1 to the tumor bedFrom1 Dec 2012 → 30 Nov 2016Funding: IWT personal funding - specialisation scholarships
- Novel molecular intervention technology for infectious and allergic respiratory diseasesFrom1 Jan 2012 → 31 Oct 2016Funding: BOF - Concerted Research Project from 1994
- Development and evaluation of particulate formulations for the selective delivery of antigens and immunpotentiators towards dendritic cells.From1 Oct 2010 → 1 Oct 2012Funding: BOF - Doctoral projects
- Synthetic mycolic acids for therapy of asthma and as adjuvants for vaccinationFrom15 Jun 2008 → 14 Jun 2009Funding: IOF - Industrial Research Fund
Publications
41 - 50 of 55
- Polyelectrolyte Microcapsules as Antigen Delivery Vehicles To Dendritic Cells: Uptake, Processing, and Cross-Presentation of Encapsulated Antigens(2009)
Authors: Stefaan De Koker, Bruno De Geest, Satwinder Singh, Riet De Rycke, Thomas Naessens, Yvette Van Kooyk, Johan Grooten
Pages: 8485 - 8489 - New asthma biomarkers: lessons from murine models of acute and chronic asthma(2009)
Authors: Emmanuel Di Valentin, Celine Crahay, Nancy Garbacki, Benoit Hennuy, Maud Gueders, Agnes Noel, Jean-Michel Foidart, Johan Grooten, Alain Colige, Jacques Piette, et al.
Pages: L185 - L197 - Cholesteroid nature of free mycolic acids from M. tuberculosis(2008)
Authors: Yolandy Benadie, Madrey Deysel, D. Gilbert R. Siko, Vanessa V. Roberts, Sandra Van Wyngaardt, Simon T. Thanyani, Gianna Sekanka, Annemieke M.C. Ten Bokum, Lynne A. Collett, Johan Grooten, et al.
Pages: 95 - 103 - Type I IFN counteracts the induction of antigen-specific immune responses by lipid-based delivery of mRNA vaccines
Authors: Charlotte Pollard, Joanna Rejman, Winni De Haes, Bernard Verrier, Ellen Van Gulck, Thomas Naessens, Pieter Bogaert, Johan Grooten, Guido Vanham, Stefaan De Koker
Pages: 251 - 259 - Alternatively activated macrophages engage in homotypic and heterotypic interactions through IL-4 and polyamine-induced E-cadherin/catenin complexes
Authors: J Van den Bossche, Pieter Bogaert, Chris Guerin, K Movahedi, R Van den Bergh, A Pereira-Fernandes, JMC Geuns, H Pircher, P Dorny, Johan Grooten, et al.
Pages: 4664 - 4674 - PH1-derived bivalent bibodies and trivalent tribodies bind differentially to shed and tumour cell-associated MUC1
Authors: Steve Schoonooghe, Ingrid Burvenich, Liesbet Vervoort, Filip De Vos, Nico Mertens, Johan Grooten
Pages: 721 - 728 - Efficient production of human bivalent and trivalent anti-MUC1 Fab-scFv antibodies in Pichia pastoris
Authors: Steve Schoonooghe, Vladimir Kaigorodov, Monika Zawisza, Caroline Dumolyn, Jurgen Haustraete, Johan Grooten, Nico Mertens
Pages: AR70-1 - AR70-14 - Challenges and advances towards the rational design of mRNA vaccines
Authors: Charlotte Pollard, Stefaan De Koker, Guido Vanham, Johan Grooten
Pages: 705 - 713 - Lipoplexes carrying mRNA encoding Gag protein modulate dendritic cells to stimulate HIV-specific immune responses
Authors: Winni De Haes, Joanna Rejman, Charlotte Pollard, Céline Merlin, Marc Vekemans, Eric Florence, Johan Grooten, Guido Vanham, Stefaan De Koker, Ellen Van Gulck
Pages: 77 - 87 - M2e-displaying virus-like particles with associated RNA promote T helper 1 type adaptive immunity against influenza A
Authors: Lorena Ibanez, Marina De Filette, Michael Schotsaert, Jessica De Sloovere, Stefan Roels, Charlotte Pollard, Johan Grooten, Walter Fiers
Patents
1 - 2 of 2