Researcher
Johan Grooten
- Disciplines:Immunology not elsewhere classified, Allergology, Adaptive immunology, Applied immunology, Autoimmunity, Immunogenetics, Transplantation immunology, Innate immunity, Vaccinology, Microbiology not elsewhere classified
Affiliations
- Department of Biomedical molecular biology (Department)
Responsible
From1 Oct 2010 → 30 Sep 2017 - Department of Biomedical molecular biology (Department)
Member
From1 Oct 2010 → 30 Sep 2017 - Department of Biomedical molecular biology (Department)
Member
From1 May 1996 → 30 Sep 2020 - Department of Plant Biotechnology and Bioinformatics (Department)
Member
From1 Jan 1993 → 30 Apr 1996
Projects
1 - 6 of 6
- Advancing novel and promising TB vaccine candidates from discovery to preclinical and early clinical developmentFrom1 Jan 2015 → 31 Dec 2018Funding: H2020 - Health, demographic change and wellbeing
- Targeting the modified innate functionality of the post-asthma alveolar macrophage for relieving Respiratory Syncytical Virus-induced astham exacerbation.From2 Jul 2013 → 31 May 2015Funding: Foundations, funds and other with scientific goal
- Increasing the efficiency of RNA-cancer vaccination by modulation of type-I-IFN activity, and interference with PD-LI / PD-1 to the tumor bedFrom1 Dec 2012 → 30 Nov 2016Funding: IWT personal funding - specialisation scholarships
- Novel molecular intervention technology for infectious and allergic respiratory diseasesFrom1 Jan 2012 → 31 Oct 2016Funding: BOF - Concerted Research Project from 1994
- Development and evaluation of particulate formulations for the selective delivery of antigens and immunpotentiators towards dendritic cells.From1 Oct 2010 → 1 Oct 2012Funding: BOF - Doctoral projects
- Synthetic mycolic acids for therapy of asthma and as adjuvants for vaccinationFrom15 Jun 2008 → 14 Jun 2009Funding: IOF - Industrial Research Fund
Publications
11 - 20 of 55
- Coadministration of a plasmid encoding HIV-1 Gag enhances the efficacy of cancer DNA vaccines(2016)
Authors: Laure Lambricht, Kevin Vanvarenberg, Ans De Beuckelaer, Lien Van Hoecke, Johan Grooten, Bernard Ucakar, Pascale Lipnik, Niek Sanders, Stefan Lienenklaus, Véronique Préat, et al.
Pages: 1686 - 1696 - Cholesterol-sensing liver X receptors stimulate Th2-driven allergic eosinophilic asthma in mice(2016)
Authors: Muriel Smet, Lien Van Hoecke, Ans De Beuckelaer, Seppe Vander Beken, Thomas Naessens, Karl Vergote, Monique Willart, Jan-Ake Gustafsson, Knut R Steffensen, Johan Grooten
Pages: 350 - 361 - pH-degradable imidazoquinoline-ligated nanogels for lymph node-focused immune activation(2016)
Authors: Lutz Nuhn, Nane Vanparijs, Ans De Beuckelaer, Lien Lybaert, Glenn Verstraete, Kim Deswarte, Stefan Lienenklaus, Nikunj M Shukla, Alex CD Salyer, Johan Grooten, et al.
Pages: 8098 - 8103 - Spontaneous protein adsorption on graphene oxide nanosheets allowing efficient intracellular vaccine protein delivery(2016)
Authors: Hui Li, Kaat Fierens, Zhiyue Zhang, Nane Vanparijs, Katleen Van Steendam, Natalia Feiner Gracia, Thomas De Beer, Ans De Beuckelaer, Stefaan De Koker, Dieter Deforce, et al.
Pages: 1147 - 1155 - GM-CSF treatment prevents respiratory syncytial virusU+2013 induced pulmonary exacerbation responses in postallergic mice by stimulating alveolar macrophage maturation(2016)
Authors: Thomas Naessens, Muriel Smet, Charlotte Pollard, Lien Van Hoecke, Ans De Beuckelaer, Monique Willart, Stefaan De Koker, Johan Grooten
Pages: 700 - 709 - Mycobacterium tuberculosis-associated synthetic mycolates differentially exert immune stimulatory adjuvant activity(2016)
Authors: Muriel Smet, Charlotte Pollard, Ans De Beuckelaer, Lien Van Hoecke, Seppe Vander Beken, Stefaan De Koker, Juma'a R Al Dulayymi, Kris Huygen, Jan Verschoor, Mark S Baird, et al.
Pages: 2149 - 2154 - Vaccination with necroptotic cancer cells induces efficient anti-tumor immunity(2016)
Authors: Tania Love Aaes, Agnieszka Kaczmarek, Tinneke Delvaeye, Bram De Craene, Stefaan De Koker, Liesbeth Heyndrickx, Iris Delrue, Joachim Taminau, Bartosz Wiernicki, Philippe De Groote, et al.
Pages: 274 - 287 - Hybrid pulmonary surfactant-coated nanogels mediate efficient in vivo delivery of siRNA to murine alveolar macrophages(2015)
Authors: Lynn De Backer, Thomas Naessens, Stefaan De Koker, Elisa Zagato, Johan Grooten, Koen Raemdonck
Pages: 53 - 63 - The site of administration influences both the type and the magnitude of the immune response induced by DNA vaccine electroporation(2015)
Authors: Gaëlle Vandermeulen, Kevin Vanvarenberg, Ans De Beuckelaer, Stefaan De Koker, Laure Lambricht, Catherine Uyttenhove, Anca Reschner, Alain Vanderplasschen, Johan Grooten, Véronique Préat
Pages: 3179 - 3185 - E-cadherin expression in macrophages dampens their inflammatory responsiveness in vitro, but does not modulate M2-regulated pathologies in vivo(2015)
Authors: Jan Van den Bossche, Damya Laoui, Thomas Naessens, Hermelijn H Smits, Cornelis H Hokke, Benoit Stijlemans, Johan Grooten, Patrick De Baetselier, Jo A Van Ginderachter
Patents
1 - 2 of 2