Researcher
Johan Grooten
- Disciplines:Immunology not elsewhere classified, Allergology, Adaptive immunology, Applied immunology, Autoimmunity, Immunogenetics, Transplantation immunology, Innate immunity, Vaccinology, Microbiology not elsewhere classified
Affiliations
- Department of Biomedical molecular biology (Department)
Responsible
From1 Oct 2010 → 30 Sep 2017 - Department of Biomedical molecular biology (Department)
Member
From1 Oct 2010 → 30 Sep 2017 - Department of Biomedical molecular biology (Department)
Member
From1 May 1996 → 30 Sep 2020 - Department of Plant Biotechnology and Bioinformatics (Department)
Member
From1 Jan 1993 → 30 Apr 1996
Projects
1 - 6 of 6
- Advancing novel and promising TB vaccine candidates from discovery to preclinical and early clinical developmentFrom1 Jan 2015 → 31 Dec 2018Funding: H2020 - Health, demographic change and wellbeing
- Targeting the modified innate functionality of the post-asthma alveolar macrophage for relieving Respiratory Syncytical Virus-induced astham exacerbation.From2 Jul 2013 → 31 May 2015Funding: Foundations, funds and other with scientific goal
- Increasing the efficiency of RNA-cancer vaccination by modulation of type-I-IFN activity, and interference with PD-LI / PD-1 to the tumor bedFrom1 Dec 2012 → 30 Nov 2016Funding: IWT personal funding - specialisation scholarships
- Novel molecular intervention technology for infectious and allergic respiratory diseasesFrom1 Jan 2012 → 31 Oct 2016Funding: BOF - Concerted Research Project from 1994
- Development and evaluation of particulate formulations for the selective delivery of antigens and immunpotentiators towards dendritic cells.From1 Oct 2010 → 1 Oct 2012Funding: BOF - Doctoral projects
- Synthetic mycolic acids for therapy of asthma and as adjuvants for vaccinationFrom15 Jun 2008 → 14 Jun 2009Funding: IOF - Industrial Research Fund
Publications
1 - 10 of 55
- Aspergillus fumigatus recognition by dendritic cells negatively regulates allergic lung inflammation through a TLR2/MyD88 pathway(2021)
Authors: Pauline Percier, Sofie De Prins, Giresse Tima, Rudi Beyaert, Johan Grooten, Marta Romano, Olivier Denis
Pages: 39 - 49 - Post-PEGylated and crosslinked polymeric ssRNA nanocomplexes as adjuvants targeting lymph nodes with increased cytolytic T cell inducing properties(2018)
Authors: Bo Lou, Ans De Beuckelaer, George Dakwar, Katrien Remaut, Johan Grooten, Kevin Braeckmans, Bruno De Geest, Enrico Mastrobattista, Stefaan De Koker, Wim E. Hennink
Pages: 73 - 83 - Treatment with mRNA coding for the necroptosis mediator MLKL induces antitumor immunity directed against neo-epitopes(2018)
Authors: Lien Van Hoecke, Peter Vandenabeele, Johan Grooten, Jan Tavernier, Stefaan De Koker
- Type I interferons modulate CD8U+207A T cell immunity to mRNA vaccines(2017)
Authors: Ans De Beuckelaer, Johan Grooten, Stefaan De Koker
Pages: 216 - 226 - Mycolates of Mycobacterium tuberculosis modulate the flow of cholesterol for bacillary proliferation in murine macrophages(2017)
Authors: Ilke Vermeulen, Mark Baird, Juma Al-Dulayymi, Muriel Smet, Jan Verschoor, Johan Grooten
Pages: 709 - 718 - Arginine-rich peptide-based mRNA nanocomplexes efficiently instigate cytotoxic T cell immunity dependent on the amphipathic organization of the peptide(2017)
Authors: Vimal Kumar Udhayakumar, Ans De Beuckelaer, Joanne McCaffrey, Cian M McCrudden, Jonathan L Kirschman, Daryll Vanover, Lien Van Hoecke, Kim Deswarte, Bruno De Geest, Stefan Lienenklaus, et al.
- Inflammatory monocytes regulate Th1 oriented immunity to CpG adjuvanted protein vaccines through production of IL-12(2017)
Authors: Stefaan De Koker, Lien Van Hoecke, Ans De Beuckelaer, Kim Deswarte, Monique Willart, Pieter Bogaert, Thomas Naessens, Bruno De Geest, Johan Grooten
- Type I interferons interfere with the capacity of mRNA lipoplex vaccines to elicit cytolytic T cell responses(2016)
Authors: Ans De Beuckelaer, Charlotte Pollard, Lien Van Hoecke, Vimal Kumar Udhayakumar, Muriel Smet, Niek Sanders, Stefan Lienenklaus, Siegfried Weiss, Guido Vanham, Johan Grooten, et al.
Pages: 2012 - 2020 - pH-Degradable mannosylated nanogels for dendritic cell targeting(2016)
Authors: Ruben De Coen, Nane Vanparijs, Martijn Risseeuw, Lien Lybaert, Benoit Louage, Stefaan De Koker, Vimal Kumar Udhayakumar, Johan Grooten, Leeanne Taylor, Neil Ayres, et al.
Pages: 2479 - 2488 - Engineering polymer hydrogel nanoparticles for lymph node-targeted delivery(2016)
Authors: Stefaan De Koker, Jivei Cui, Nane Vanparijs, Lorenzo Albertazzi, Johan Grooten, Frank Caruso, Bruno De Geest
Pages: 1334 - 1339
Patents
1 - 2 of 2