Researcher
Jo Vandesompele
- Keywords:non-coding RNA, RNA, Applied bioinformatics, DNA, cancer, liquid biopsy, DNA and RNA sequencing, PCR
- Disciplines:Cancer diagnosis, Cancer prevention, Cancer epidemiology, Cancer biology, Cancer therapy, Analysis of next-generation sequence data, Bioinformatics of disease, Bioinformatics data integration and network biology, Data visualisation and high-throughput image analysis, Ontologies, data curation and text mining, Development of bioinformatics software, tools and databases, Clinical genetics and molecular diagnostics, Oncology not elsewhere classified, Medical epigenomics, Medical metagenomics, Medical genomics, Single-cell data analysis, Bioinformatics and computational biology not elsewhere classified, Structural bioinformatics and computational proteomics
Affiliations
- Department of Biomolecular Medicine (Department)
Member
From1 Oct 2018 → Today - Department of Pediatrics and medical genetics (Department)
Member
From1 Oct 1997 → 30 Sep 2018
Projects
21 - 30 of 32
- Long noncoding RNAs in cancer: deciphering the functional role of the dark matter of the human cancer genomeFrom1 Jan 2016 → 31 Dec 2022Funding: BOF - Concerted Research Project from 1994
- Fair Anneleen Decock: Pioneering the neuroblastoma DNA methylome: identify biological differences between subgroups and optimization biomerkerdetectie plasma.From1 Oct 2015 → 30 Sep 2016Funding: FWO Humanitarian research project Stand up against Cancer
- Decoding long non-coding RNAs in cancer - Foundation against cancerFrom1 Jan 2015 → 31 Dec 2018Funding: Foundations, funds and other with scientific goal
- LncRNAs as therapeutic targets and diagnostic biomarkers for advanced melanomaFrom1 Apr 2014 → 30 Jun 2016Funding: IOF - Industrial Research Fund
- Improved outcome prediction of children with neuroblastoma using an integrated m/miRNA and DNA methylation signature (Stichting tegen Kanker)From1 Jan 2013 → 31 Dec 2022Funding: Foundations, funds and other with scientific goal
- Integrated biology-driven diagnostic and therapeutic management of neuroblastoma (Stichting tegen Kanker)From1 Jan 2013 → 31 Dec 2015Funding: Foundations, funds and other with scientific goal
- Discovery and functional analysis of TP53 network long non-coding RNA genes in cancerFrom1 Oct 2012 → 1 Oct 2014Funding: BOF - Other initiatives
- Development and application of digital PCRFrom15 Jun 2012 → 30 Jun 2016Funding: BOF - Other initiatives
- Human exome resequencing PCR assay designFrom15 Apr 2012 → 14 Oct 2013Funding: IOF - Industrial Research Fund
- Molecular phenotyping and in vivo assessment of miRNA perturbation in neuroblastomaFrom30 Dec 2010 → 30 Dec 2014Funding: Foundations, funds and other with scientific goal
Publications
1 - 10 of 120
- Nationwide quality assurance of high-throughput diagnostic molecular testing during the SARS-CoV-2 pandemic : role of the Belgian National Reference Centre(2024)
Authors: Reile Janssen, Lize Cuypers, Lies Laenen, Els Keyaerts, Kurt Beuselinck, Sunita Janssenswillen, Bram Slechten, Jannes Bode, Elke Wollants, Kristel Van Laethem, et al.
- HTSplotter : an end-to-end data processing, analysis and visualisation tool for chemical and genetic in vitro perturbation screening(2024)
Authors: Carolina de Carvalho Nunes, Jasper Anckaert, Fanny De Vloed, Jolien De Wyn, Kaat Durinck, Jo Vandesompele, Franki Speleman, Vanessa Vermeirssen
- Nucleic acid degradation as barrier to gene delivery : a guide to understand and overcome nuclease activity(2024)
Authors: Heyang Zhang, Jo Vandesompele, Kevin Braeckmans, Stefaan De Smedt, Katrien Remaut
Pages: 317 - 360 - Blocking abundant RNA transcripts by high-affinity oligonucleotides during transcriptome library preparation(2023)
Authors: Celine Everaert, Jasper Verwilt, Kimberly Verniers, Niels Vandamme, Alvaro Marcos Rubio, Jo Vandesompele, Pieter Mestdagh
- Performance evaluation of RNA purification kits and blood collection tubes in the Extracellular RNA Quality Control (exRNAQC) study(2023)
Authors: Anneleen Decock, Olivier De Wever, Celine Everaert, Hetty Helsmoortel, An Hendrix, Pieter Mestdagh, Annelien Morlion, Jo Vandesompele, Ruben Van Paemel, Francisco Avila Cobos, et al.
Number of pages: 1 - Performance evaluation of RNA purification kits and blood collection tubes in the Extracellular RNA Quality Control (exRNAQC) study(2023)
Authors: Anneleen Decock, Olivier De Wever, Celine Everaert, Hetty Helsmoortel, An Hendrix, Pieter Mestdagh, Annelien Morlion, Jo Vandesompele, Ruben Van Paemel, Francisco Avila Cobos, et al.
Number of pages: 1 - Large-scale benchmarking of circRNA detection tools reveals large differences in sensitivity but not in precision(2023)
Authors: Marieke Vromman, Jasper Anckaert, Stefania Bortoluzzi, Alessia Buratin, Chia-Ying Chen, Qinjie Chu, Trees-Juen Chuang, Roozbeh Dehghannasiri, Christoph Dieterich, Xin Dong, et al.
Pages: 1159 - 1169 - Exploring the cell-free total RNA transcriptome in diffuse large B-cell lymphoma and primary mediastinal B-cell lymphoma patients as biomarker source in blood plasma liquid biopsies(2023)
Authors: Philippe Decruyenaere, Edoardo Giuili, Kimberly Verniers, Jasper Anckaert, Katrien De Grove, Malaïka Van der Linden, Dries Deeren, Jo Van Dorpe, Fritz Offner, Jo Vandesompele
- Circular RNA detection pipelines yield divergent sets of circular RNAs(2023)
Authors: Marieke Vromman, Jo Vandesompele
Pages: 1135 - 1136 - Exploration of neuroblastoma xenograft models for tumor extracellular RNA profiling in murine blood plasma(2023)
Authors: Jill Deleu, Hanne Van Droogenbroeck, Jasper Anckaert, Anneleen Decock, Jilke De Wilde, Kaat Durinck, Liselot Mus, Justine Nuytens, Muhammad Rishfi, Kathleen Schoofs, et al.
Patents
1 - 6 of 6
- Inhibition of a lncRNA for treatment of melanoma (Inventor)
- Biomarkers for disease burden of neuroblastoma (Inventor)
- Usages of recombinant extracellular vesicles (Inventor)
- Biomarkers for disease burden of neuroblastoma (Inventor)
- Usages of recombinant extracellular vesicles (Inventor)
- Inhibition of a lncRNA for treatment of melanoma (Inventor)