Researcher
Jo Van Ginderachter
- Keywords (Vrije Universiteit Brussel):Applied biological sciences, biotechnology
- Disciplines (Flanders Institute for Biotechnology):Analysis of next-generation sequence data, Adaptive immunology, Bacteriology
- Disciplines (Vrije Universiteit Brussel):Applied immunology
Affiliations
- Cellular and Molecular Immunology (Research group)
Responsible
From1 Oct 1995 → Today - Department of Bio-engineering Sciences (Department)
Member
From1 Jan 2024 → Today - Department of Bio-engineering Sciences (Department)
Member
From1 Oct 2019 → 31 Dec 2023 - Department of Bio-engineering Sciences (Department)
Member
From8 Apr 2019 → 30 Sep 2019 - Van Ginderachter Lab (Research group)
Responsible
From1 Jan 2017 → Today - Department of Bio-engineering Sciences (Department)
Member
From1 Oct 2012 → Today - Department of Bio-engineering Sciences (Department)
Member
From1 Oct 2010 → 20 Oct 2022 - Department of Bio-engineering Sciences (Department)
Member
From1 Oct 1999 → 30 Sep 2014
Projects
11 - 20 of 26
- GEAR: Integrating a multimodal approach to address current challenges in immunotherapy (INTEGRAL)From1 Jan 2020 → TodayFunding: IOF - technology validation in real environment, IOF - mandates
- A novel cancer therapy that selectively targets tumor-infiltrating regulatory T cellsFrom1 Nov 2019 → 31 Oct 2023Funding: FWO fellowships
- Blockade of the VSIG4 immune checkpoint molecule as novel cancer therapyFrom1 Jan 2019 → 31 Dec 2022Funding: FWO fellowships
- Elucidating the role of CD11b+ conventional dendritic cells (cDC2) in the tumor microenvironment and their potential use as tumor vaccine.From1 Jan 2019 → 31 Dec 2022Funding: FWO research project (including WEAVE projects)
- IOF Accelerator: Camelidae-derived single domain antibody fragments for theranosis of cancerFrom21 Dec 2018 → 20 Dec 2021Funding: IOF - technology validation in real environment
- FWO Hercules MZW: Platform for cell analysis after radioactivity based Molecular Imaging and targeted Therapy of cancer (PeRMIT)From1 May 2018 → 30 Apr 2023Funding: FWO Medium Size Research Infrastructure
- FWO Hercules MZW: Light sheet fluorescence microscopy in life sciences and medical researchFrom1 May 2018 → 30 Apr 2022Funding: FWO Medium Size Research Infrastructure
- Strategic Research Programme: Molecular Imaging and targeting of macrophages in Inflammation (ITARMI)From1 Nov 2017 → 31 Oct 2022Funding: University - Project driven research
- Targeted killing or reprogramming of tumor-associated macrophages with multifunctional nanomedicinesFrom1 Jan 2017 → 31 Mar 2022Funding: FWO research project (including WEAVE projects)
- Blockade of the CCR8 chemokine receptor as novel cancer therapyFrom1 Jan 2017 → 31 Dec 2020Funding: FWO fellowships
Publications
1 - 10 of 101
- Q586B2 is a crucial virulence factor during the early stages of Trypanosoma brucei infection that is conserved amongst trypanosomatids(2024)
Authors: Benoit Stijlemans, Patrick De Baetselier, Inge Van Molle, Laurence Lecordier, Erika Hendrickx, Ema Romão, Cecile Vincke, Wendy Baetens, Steve Schoonooghe, Gholamreza Hassanzadeh-Ghassabeh, et al.
- Phase I Study of [68Ga]Ga-Anti-CD206-sdAb for PET/CT Assessment of Protumorigenic Macrophage Presence in Solid Tumors (MMR Phase I)(2023)
Authors: Odrade Gondry, Catarina Xavier, Laurens Raes, Johannes Heemskerk, Nick Devoogdt, Hendrik Everaert, Karine Breckpot, Quentin Lecocq, Lore Decoster, Christel Fontaine, et al.
Pages: 1378-1384 - Ontogeny, functions and reprogramming of Kupffer cells upon infectious disease(2023)
Authors: Mohamed Musrati, Patrick De Baetselier, Kiavash Movahedi, Jo A Van Ginderachter
- Flt3L therapy increases the abundance of Treg-promoting CCR7+ cDCs in preclinical cancer models(2023)
Authors: Emile J Clappaert, Daliya Kancheva, Jan Brughmans, Ayla Debraekeleer, Pauline M R Bardet, Yvon Elkrim, Dagmar Lacroix, Maida Zivalj, Ahmed E. I. Hamouda, Jo A Van Ginderachter, et al.
- Whole-mouse clearing and imaging at the cellular level with vDISCO(2023)
Authors: Ruiyao Cai, Zeynep Ilgin Kolabas, Chenchen Pan, Hongcheng Mai, Shan Zhao, Doris Kaltenecker, Fabian F Voigt, Muge Molbay, Tzu-Lun Ohn, Cecile Vincke, et al.
Pages: 1197-1242 - Hallmarks of Cancer Affected by the MIF Cytokine Family(2023)
Authors: Romina Mora Barthelmess, Benoit Stijlemans, Jo A Van Ginderachter
Pages: 1-25 - Size-advantage of monovalent nanobodies against the macrophage mannose receptor for deep tumor penetration and tumor-associated macrophage targeting(2023)
Authors: Marco Erreni, Francesca D'Autilia, Roberta Avigni, Evangelia Bolli, Sana M Arnouk, Kiavash Movahedi, Pieterjan Debie, Achille Anselmo, Raffaella Parente, Cecile Vincke, et al.
Pages: 355-373 - Macrophages in the brain(2023)
Authors: Karen De Vlaminck, Jo A Van Ginderachter, Kiavash Movahedi
Number of pages: 173 - Dendritic cell-based cancer immunotherapy: increasing intratumoral dendritic cell abundance and potential for vaccination(2023)
Authors: Emile J Clappaert, Damya Laoui, Jo A Van Ginderachter
Number of pages: 171 - The Interface of Tumour-Associated Macrophages with Dying Cancer Cells in Immuno-Oncology(2022)
Authors: Isaure Vanmeerbeek, Jannes Govaerts, Raquel S Laureano, Jenny Sprooten, Stefan Naulaerts, Daniel M Borras, Damya Laoui, Massimiliano Mazzone, Jo A Van Ginderachter, Abhishek D Garg
Patents
1 - 6 of 6
- Tumor-associated dendritic cell preparations and uses thereof (Inventor)
- Non-blocking human ccr8 binders (Inventor)
- Human ccr8 binders (Inventor)
- A ccr8 antagonist antibody in combination with a lymphotoxin beta receptor agonist antibody in therapy against cancer (Inventor)
- Anti-macrophage mannose receptor immunoglobulin single variable domains for targeting and in vivo imaging of tumor-associated macrophages (Inventor)
- Murine cross-reactive human ccr8 binders (Inventor)