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Researcher
Jessy Elst
- Research Expertise:After completing my biomedical education with specialization in clinical sciences at the University of Antwerp in 2017, I worked on and completed my PhD project at the University of Antwerp in the laboratory of Immunology and Allergology. After obtaining my PhD, I started as a postdoc researcher in the same laboratory. I conduct fundamental and translational research that mainly focuses on the activation and inhibition mechanisms of basophils and mast cells in anaphylaxis, clonal mast cell disorders and hypersensitivity reactions to drugs and Hymenoptera. In this research, mast cells are cultured from CD34+ progenitor cells isolated from peripheral blood or bone marrow. The analyzes of membrane characteristics, functional assays and cell culture are performed at the single cell level using flow cytometry. In addition, I have extensive experience with a human mast cell knock-down model using electroporation which I developed. Lastly, I started recently with performing genomics and transcriptomics in mast cells related diseases.
- Keywords:HYPERSENSITIVITY, IMMUNOLOGY, ALLERGOLOGY, Medicine
- Disciplines:Diagnostics, Immunology, Laboratory medicine, Molecular and cell biology, Cell signalling, Adaptive immunology, Allergology, Innate immunity
- Research techniques:cell culture Flow cytometry Electroporation
- Users of research expertise:Research groups PhD students Master students