Researcher
Jef Rozenski
- Disciplines:Biomarker discovery and evaluation, Drug discovery and development, Medicinal products, Pharmaceutics, Pharmacognosy and phytochemistry, Pharmacology, Pharmacotherapy, Toxicology and toxinology, Other pharmaceutical sciences, Bioinformatics and computational biology
Affiliations
- Medicinal Chemistry (Rega Institute) (Division)
Member
From1 Oct 1999 → Today
Projects
1 - 10 of 11
- Exploration of the pharmacokinetics of clindamycin and its metabolites in special patients: from bioanalysis to clinical relevanceFrom1 Oct 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- An NMR facility tailored for biomedical researchFrom1 May 2020 → TodayFunding: FWO Medium Size Research Infrastructure
- Streamlining the route of phosphonate XNA from chemistry to applicationFrom1 Oct 2019 → TodayFunding: BOF - projects, IOF - technology concept exploration
- Directed evolution of bioactive compounds: Azol(in)e-containing post-translationally modified peptidesFrom1 Apr 2019 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Drug design strategies against newly emerging viral diseasesFrom17 Oct 2016 → 30 Oct 2020Funding: Own budget, for example: patrimony, inscription fees, gifts
- Development of XNA ligases as tools for synthetic biologyFrom22 Sep 2015 → 17 Oct 2019Funding: BOF - Doctoral projects, BOF - doctoral mandates
- Development of a xenozyme and an XNA ligase.From1 Oct 2014 → 30 Sep 2018Funding: BOF - Concerted Research Project from 1994
- Selection of nucleic acid chemistry for therapeutic aptamer design.From1 Jan 2014 → 31 Dec 2017Funding: FWO research project
- Oligonucleotides as biochemical and therapeutic tools.From1 Jan 2011 → 31 Dec 2014Funding: FWO research project
- Liquid chromatogram couples to a mass spectrometer for bioanalytical applications.From22 Jul 2010 → 22 Jan 2017Funding: Hercules - Small and Medium size research infrastructure
Publications
1 - 10 of 76
- Overview of in-capillary enzymatic reactions using capillary electrophoresis(2021)
Authors: Jozef Rozenski, Ann Van Schepdael
Pages: 57 - 73Number of pages: 17 - Exploring the dNTP -binding site of HIV-1 reverse transcriptase for inhibitor design(2021)
Authors: Weijie Gu, Sergio Martinez, Abhimanyu Kumar Singh, Jozef Rozenski, Dominique Schols, Piet Herdewyn, Kalyan Das, Steven De Jonghe
Number of pages: 19 - Noncanonical DNA polymerization by aminoadenine-based siphoviruses(2021)
Authors: Jozef Rozenski, Piet Herdewyn
Pages: 520 - +Number of pages: 31 - Synthesis and structure-activity studies of novel anhydrohexitol-based Leucyl-tRNA synthetase inhibitors(2021)
Authors: Dries De Ruysscher, Luping Pang, Stijn Lenders, Jozef Rozenski, Sergei Strelkov, Arthur Van Aerschot
Number of pages: 17 - Recent progress in the LC-MS/MS analysis of oxidative stress biomarkers(2020)
Authors: Asmin Andries, Jozef Rozenski, Pieter Vermeersch, Djalila Mekahli, Ann Van Schepdael
Pages: 402 - 428Number of pages: 27 - Structural Studies of HNA Substrate Specificity in Mutants of an Archaeal DNA Polymerase Obtained by Directed Evolution(2020)
Authors: Jozef Rozenski, Mikhail Abramov, Vitor Bernardes Pinheiro
Number of pages: 25 - Drug design strategies against newly emerging viral diseases(2020)
Authors: Muhammad Usman Mirza, Matheus Froeyen, Jozef Rozenski
- Synthesis and Biological Evaluation of 1,3-Dideazapurine-Like 7-Amino-5-Hydroxymethyl-Benzimidazole Ribonucleoside Analogues as Aminoacyl-tRNA Synthetase Inhibitors(2020)
Authors: Luping Pang, Steff De Graef, Eveline Lescrinier, Jozef Rozenski, Sergei Strelkov, Arthur Van Aerschot
Number of pages: 24 - Phenyltriazole-functionalized sulfamate inhibitors targeting tyrosyl- or isoleucyl-tRNA synthetase(2020)
Authors: Dries De Ruysscher, Luping Pang, Charles-Alexandre Mattelaer, Steff De Graef, Jozef Rozenski, Sergei Strelkov, Eveline Lescrinier, Arthur Van Aerschot
Number of pages: 15 - Synthesis and Biological Evaluation of Lipophilic Nucleoside Analogues as Inhibitors of Aminoacyl-tRNA Synthetases(2019)
Authors: Manesh Nautiyal, Steff De Graef, Luping Pang, Jozef Rozenski, Arthur Van Aerschot
Number of pages: 23