Researcher
Jean-Marc Taymans
- Keywords:Biomedical sciences (incl. biochemistry)
Affiliations
- Research Group for Neurobiology and Gene Therapy (Division)
Member
From1 Oct 2005 → 30 Sep 2014
Projects
1 - 3 of 3
- Study of the cellular signaling processes of the Parkinsons disease protein LRRK2.From1 Apr 2012 → 31 Mar 2014Funding: Other federal public and semi-governmental institutions
- Unraveling the cellular signaling of neurodegeneration in LRRK2 Parkinson's disease.From1 Jan 2012 → 31 Dec 2014Funding: FWO research grant KAN
- Structural and functional study of the central GTPase/kinase catalytic core of LRRK2, a Parkinson's disease-linked protein.From1 Jan 2009 → 31 Dec 2014Funding: FWO research project (including WEAVE projects)
Publications
1 - 10 of 32
- Chemical genetic approach identifies microtubule affinity-regulating kinase 1 as a leucine-rich repeat kinase 2 substrate(2015)
Authors: Lauran Reyniers, Evy Lobbestael, Jean-Marc Taymans, Veerle Baekelandt
Pages: 2980 - 2992 - Chemical genetic approach identifies microtubule affinity-regulating kinase 1 as a leucine-rich repeat kinase 2 substrate(2015)
Authors: Petranka Krumova, Lauran Reyniers, Marc Meyer, Evy Lobbestael, Daniela Stauffer, Bertran Gerrits, Lionel Muller, Sjouke Hoving, Klemens Kaupmann, Johannes Voshol, et al.
Pages: 2980 - 2992 - Indolinone based LRRK2 kinase inhibitors with a key hydrogen bond(2014)
Authors: Jean-Marc Taymans, Veerle Baekelandt
Pages: 4630 - 4637 - Differential protein-protein interactions of LRRK1 and LRRK2 indicate roles in distinct cellular signaling pathways(2014)
Authors: Lauran Reyniers, Evy Lobbestael, Rita Derua, Etienne Waelkens, Veerle Baekelandt, Jean-Marc Taymans
Pages: 239 - 250 - In silico, in vitro and cellular analysis with a kinome-wide inhibitor panel correlates cellular LRRK2 dephosphorylation to inhibitor activity on LRRK2(2014)
Authors: Renée Vancraenenbroeck, Joren De Raeymaecker, Evy Lobbestael, Marc De Maeyer, Arnout Voet, Veerle Baekelandt, Jean-Marc Taymans
Pages: 51 - Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease(2014)
Authors: Evy Lobbestael, Veerle Baekelandt, Jean-Marc Taymans
Pages: 2626 - 2631 - In vitro phosphorylation does not influence the aggregation kinetics of WT α-synuclein in contrast to its phosphorylation mutants(2014)
Authors: Sarah Schreurs, Rita Derua, Etienne Waelkens, Jean-Marc Taymans, Veerle Baekelandt, Yves Engelborghs
Pages: 1040 - 1067 - A direct interaction between leucine-rich repeat kinase 2 and specific β-tubulin isoforms regulates tubulin acetylation(2014)
Authors: Jean-Marc Taymans, Veerle Baekelandt
Pages: 895 - 908 - Regulation and targeting of enzymes mediating Parkinson's disease pathogenesis: focus on Parkinson's disease kinases, GTPases, and ATPases(2014)
Authors: Jean-Marc Taymans, Veerle Baekelandt
Pages: 71 - Phosphatases of α-synuclein, LRRK2, and tau: important players in the phosphorylation-dependent pathology of Parkinsonism(2014)
Authors: Jean-Marc Taymans, Veerle Baekelandt