- Users of research expertise:
Jean-Claude Dujardin graduated in Zoology (Facultés Notre Dame de la Paix, Namur, Belgium) in 1983. One year later, he acquired the diploma in Tropical Medical Biology at the Institute of Tropical Medicine. He joined the ITM as assistant in 1986 and introduced molecular parasitology. From 1990 to 1992 he was a visiting scientist at the Instituto de Medicina Tropical A. von Humboldt (Lima, Peru) and in 1995 he got the degree of Doctor in Science (Zoology) at the Free University of Brussels. He is the head of the Unit of Molecular Parasitology at ITM since 2002 and became the head of the Department of Biomedical Sciences (ITM) since 2011.
He explored the diversity of Leishmania and leishmaniases for over 25 years, ‘from genomes to eco-systems’. As such, he has the relevant laboratory experience in (i) parasitology and (ii) molecular biology both in the high-tech context of a modern lab and in the working conditions of a laboratory in a tropical context. He led several international research consortia on drug resistance and molecular epidemiology of leishmaniasis. He teaches in several Belgian Universities and is part-time professor at the University of Antwerp.
- Drug resistance in leishmaniasis: mechanisms, link with survival skills, in vitro and in vivo phenotyping, experimental validation, surveillance tools, interacting closely with ‘clinomics’ line
- ‘Clinomic’ diversity in leishmania: genomic, transcriptomic, metabolomic exploitation of parasite collections linked to well-documented cohorts of patients (understanding of clinical and in vitro/vivo phenotypic diversity, parasite evolution)
- Molecular epidemiology of leishmaniasis: (i) further dissemination of standardized and QA-typing tests and (ii) application of molecular tools for characterization of transmission patterns (with a special interest for asymptomatic infections)