Researcher
Jean-Christophe Marine
- Disciplines:Biophysics, Molecular and cell biology, Laboratory medicine, Microbiology, Systems biology, Plant biology, Medicinal and biomolecular chemistry
Affiliations
- Department of Biomedical molecular biology (Department)
Member
From1 Feb 2004 → 30 Sep 2013
Projects
1 - 3 of 3
- STAND UP TO CANCER: Integration of individual cancer genes in signalisation network in pediatric tumorsFrom1 Jan 2011 → 31 Dec 2014Funding: FWO research project (including WEAVE projects)
- The role of the p53 tumour suppressor protein in epigenetic maintenance of genomic integrity via transcriptional silencing and stabilisation of heterochromatic domains.From1 Oct 2008 → 8 Jun 2012Funding: FWO fellowships, BOF - Other initiatives
- Targeting Modulators of the P53 Tumour Suppressor Pathway as a new Avenue for Cancer TreatmentFrom1 Jan 2007 → 31 Dec 2010Funding: Other federal scientific institutions
Publications
11 - 20 of 21
- TCTP protects from apoptotic cell death by antagonizing bax function(2008)
Authors: L SUSINI, S BESSE, D DUFLAUT, A LESPAGNOL, Chantal Beekman, G FIUCCI, AR ATKINSON, D BUSSO, P POUSSIN, Jean-Christophe Marine, et al.
Pages: 1211 - 1220 - Real-time qPCR as a tool for evaluating RNAi-mediated gene silencing(2008)
Authors: Pieter Mestdagh, Sarah De Clercq, Filip Pattyn, Jean-Christophe Marine
Pages: 16 - 21 - Functional analysis of the p53 pathway in neuroblastoma cells using the small-molecule MDM2 antagonist Nutlin-3
Authors: Ali Rihani, Daniel Dreidax, Sarah De Clercq, Jean-Christophe Marine, Frank Westermann
Pages: 983 - 993 - Antitumor Activity of the Selective MDM2 Antagonist Nutlin-3 Against Chemoresistant Neuroblastoma With Wild-Type p53
Authors: Jasmien Taildeman, Irina Lambertz, Liesbeth Vercruysse, Ali Rihani, Martin Michaelis, Jindrich Cinatl, Claude Cuvelier, Jean-Christophe Marine, Marc Bracke
Pages: 1562 - 1574 - Bcl-2 and accelerated DNA repair mediates resistance of hair follicle bulge stem cells to DNA-damage-induced cell death
Authors: Panagiota A Sotiropoulou, Aurelie Candi, Guilhem Mascre, Sarah De Clercq, Khalil Kass Youssef, Gaelle Lapouge, Ellen Dahl, Claudio Semeraro, Geertrui Denecker, Jean-Christophe Marine, et al.
Pages: 572 - 582 - Cop1 constitutively regulates c-Jun protein stability and functions as a tumor suppressor in mice
Authors: Domenico Migliorini, Dieter Defever, Rajesh Vyas, Geertrui Denecker, Enrico Radaelli, Aleksandra Zwolinska, Vanessa Depaepe, Tino Hochepied, William C Skarnes, Jean-Christophe Marine
Pages: 1329 - 1343 - Widespread overexpression of epitope-tagged Mdm4 does not accelerate tumor formation in vivo
Authors: Sarah De Clercq, Agniezska Gembarska, Geertrui Denecker, Marion Maetens, Michaël Naessens, Katharina Haigh, Jody Haigh, Jean-Christophe Marine
Pages: 5394 - 5405 - An illegitimate microRNA target site within the 3' UTR of MDM4 affects ovarian cancer progression and chemosensitivity
Authors: Jessica Wynendaele, Anja Böhnke, Eleonora Leucci, Søren Jensby Nielsen, Irina Lambertz, Stefanie Hammer, Nadja Sbrzesny, Dana Kubitza, Anja Wolf, Elise Gradhand, et al.
Pages: 9641 - 9649 - c-Abl Phosphorylates Hdmx and Regulates Its Interaction with p53
Authors: Valentina Zuckerman, Kristiaan Lenos, Grzegorz M. Popowicz, Isabelle Silberman, Tamar Grossman, Jean-Christophe Marine, Tad A. Holak, Aart G. Jochemsen, Ygal Haupt
Pages: 4031 - 4039 - Transforming growth factor-beta and mutant p53 conspire to induce metastasis by antagonizing p63: a (ternary) complex affair
Authors: Jean-Christophe Marine, Geert Berx
Pages: AR304-1 - AR304-2