< Back to previous page
Researcher
Jan Parys
- Disciplines:Laboratory medicine, Palliative care and end-of-life care, Regenerative medicine, Other basic sciences, Other health sciences, Nursing, Other paramedical sciences, Other translational sciences, Other medical and health sciences
Affiliations
- Laboratory of Molecular and Cellular Signaling (Division)
Member
From1 Oct 2007 → Today
Projects
1 - 10 of 17
- A kinetic, high-throughput cellular screening system (Plate Imaging Reader) for the "real time" monitoring of dynamic intracellular Ca2+ signals in living cellsFrom1 May 2020 → TodayFunding: BOF - scientific equipment program
- Bcl-2/Bcl-XL proteins as modulators of calcium signaling through IP3 receptors: from novel molecular mechanisms to implications for therapeuticsFrom1 Oct 2019 → 30 Sep 2023Funding: IOF - technology concept exploration, BOF - projects
- Physiological significance of pyruvate kinase M2 interaction with the IP3 receptor and its application as a new way to induce apoptosis.From1 Jan 2019 → 31 Dec 2022Funding: FWO research project (including WEAVE projects)
- A star is born: TBMIM5 as a novel Ca2+ channel at the inner mitochondrial membraneFrom1 Oct 2016 → 21 Jan 2021Funding: BOF - doctoral mandates
- Novel insights in the interplay between ryanodine receptors and Bcl-2 proteins.From1 Oct 2015 → 30 Sep 2016Funding: BOF - Other initiatives
- Crosstalk in the Ca2+ microdomain between lysosomes and endoplasmic reticulum controls the autophagic process.From1 Jan 2015 → 31 Dec 2018Funding: FWO research project (including WEAVE projects)
- Insights into the pathways implicated in the addiction of cancer B-cells to Bcl-2 at the endoplasmic reticulumFrom1 Oct 2014 → 30 Sep 2018Funding: FWO fellowships
- The role of lysosomal Ca2+ in the regulation of autophagyFrom1 Sep 2014 → 10 Dec 2019Funding: FWO fellowships, BOF - Doctoral projects
- A novel concept in the biology of Bcl-2 proteins: primed to death at the endoplasmic reticulum.From1 Jan 2014 → 31 Dec 2017Funding: FWO research project (including WEAVE projects)
- Interplay between the endoplasmic reticulum, Ca2+ and autophagy induced by various stressorsFrom1 Jan 2013 → 31 Dec 2016Funding: FWO research project (including WEAVE projects)
Publications
41 - 50 of 160
- Extracellular and ER-stored Ca2+ contribute to BIRD-2-induced cell death in diffuse large B-cell lymphoma cells(2018)
Authors: Rita La Rovere, Peter Vangheluwe, Jan Parys, Geert Bultynck
- Pathophysiological consequences of isoform-specific IP3 receptor mutations(2018)
Authors: Martijn Kerkhofs, Bruno Seitaj, Hristina Ivanova, Giovanni Monaco, Geert Bultynck, Jan Parys
Pages: 1707 - 1717 - Calcium signaling in health, disease and therapy Preface(2018)
Authors: Jan Parys, Geert Bultynck
Pages: 1657 - 1659 - Insights into the pathways implicated in the addiction of cancer B-cells to Bcl-2 at the endoplasmic reticulum(2018)
Authors: Mart Bittremieux, Geert Bultynck, Jan Parys
- A critical appraisal of the role of intracellular Ca2+-signaling pathways in Kawasaki disease(2018)
Authors: Ludwig Missiaen, Geert Bultynck, Jan Parys
Pages: 95 - 103 - Ca2+ signaling and cell death: Focus on the role of Ca2+ signals in the regulation of cell death & survival processes in health, disease and therapy(2018)
Authors: Jan Parys, Geert Bultynck
Pages: 1 - 2 - The regulation of autophagy by calcium signals: Do we have a consensus?(2018)
Authors: Geert Bultynck, Jan Parys
Pages: 32 - 46 - Bcl-2 inhibitors as anti-cancer therapeutics: the impact of and on calcium signaling(2018)
Authors: Tamara Vervloessem, Martijn Kerkhofs, Rita La Rovere, Flore Sneyers, Jan Parys, Geert Bultynck
Pages: 102 - 116 - Emerging molecular mechanisms in chemotherapy: Ca2+ signaling at the mitochondria-associated endoplasmic reticulum membranes(2018)
Authors: Martijn Kerkhofs, Mart Bittremieux, Jan Parys, Geert Bultynck
- The mycotoxin phomoxanthone A disturbs the form and function of the inner mitochondrial membrane(2018)
Authors: Jan Parys