Researcher
Janik Puttemans
- Research Expertise:
Working in the field of preclinical nuclear and molecular diagnostics and cancer therapy using single-domain antibody fragments.
- Keywords:Medicine
- Disciplines:Diagnostic radiology, Industrial biotechnology diagnostics, Cancer therapy, Image-guided interventions, Molecular diagnostics, Radiation therapy, Nuclear imaging
- Users of research expertise:
Working in the field of preclinical nuclear and molecular diagnostics and cancer therapy using single-domain antibody fragments.
Affiliations
- Molecular Imaging and Therapy (Research group)
Member
From1 Jan 2023 → Today - Medical Imaging (Research group)
Member
From1 Oct 2015 → Today - Supporting clinical sciences (Department)
Member
From1 May 2024 → Today - Clinical sciences (Department)
Member
From15 Jun 2021 → Today - Supporting clinical sciences (Department)
Member
From1 Jan 2020 → 31 Dec 2020 - Supporting clinical sciences (Department)
Member
From1 Jan 2016 → 31 Dec 2023 - Supporting clinical sciences (Department)
Member
From1 Oct 2015 → 20 Oct 2022 - Supporting clinical sciences (Department)
Member
From1 Oct 2015 → 15 Oct 2015 - Faculty of Medicine and Pharmacy (Faculty)
Member
From16 Sep 2015 → 4 Mar 2021
Projects
1 - 1 of 1
- FWO-SB-Beurs: Nanobodies targeting mutant-EGFR as a unique tumor-restrictive vehicle for targeted therapy of glioblastomaFrom1 Jan 2016 → 31 Dec 2019Funding: FWO fellowships
Publications
1 - 10 of 17
- Generation and Characterization of Novel Pan-Cancer Anti-uPAR Fluorescent Nanobodies as Tools for Image-Guided Surgery(2024)
Authors: Lukasz Mateusiak, Sam Floru, Timo W M De Groof, Janne Wouters, Noemi Declerck, Pieterjan Debie, Simone Janssen, Katty Zeven, Karine Breckpot, Janik Puttemans, et al.
- Anti-Idiotypic VHHs and VHH-CAR-T Cells to Tackle Multiple Myeloma: Different Applications Call for Different Antigen-Binding Moieties(2024)
Authors: Heleen Hanssens, Fien Meeus, Emma Lisette Gesquiere, Janik Puttemans, Y De Vlaeminck, Kim De Veirman, Karine Breckpot, Nick Devoogdt
- Scrutiny of chimeric antigen receptor activation by the extracellular domain(2024)
Authors: Heleen Hanssens, Fien Meeus, Y De Vlaeminck, Q Lecocq, Janik Puttemans, Pieterjan Debie, Timo W M De Groof, Cleo Goyvaerts, Kim De Veirman, Karine Breckpot, et al.
- Targeted α-Therapy Using 225Ac Radiolabeled Single-Domain Antibodies Induces Antigen-Specific Immune Responses and Instills Immunomodulation Both Systemically and at the Tumor Microenvironment(2023)
Authors: T Ertveldt, Ahmet Krasniqi, Hannelore Ceuppens, Janik Puttemans, Yana Dekempeneer, Kevin De Jonghe, Wout De Mey, Q Lecocq, Y De Vlaeminck, R M Awad, et al.
Pages: 751-758 - The road to personalized myeloma medicine(2022)
Authors: Janik Puttemans, Benoit Stijlemans, Marleen Keyaerts, Sam Vander Meeren, Wim Renmans, Karel Fostier, Pieterjan Debie, Heleen Hanssens, Magdalena Rodak, Marek Pruszynski, et al.
Pages: 159-169 - Imaging of Glioblastoma Tumor-Associated Myeloid Cells Using Nanobodies Targeting Signal Regulatory Protein Alpha(2021)
Authors: Karen De Vlaminck, Ema Romão, Janik Puttemans, Ana Rita Pombo Antunes, Daliya Kancheva, Isabelle Scheyltjens, Jo A Van Ginderachter, Serge Muyldermans, Nick Devoogdt, Kiavash Movahedi, et al.
- Evaluation of single domain antibodies as nuclear tracers for imaging of the immune checkpoint receptor human lymphocyte activation gene-3 in cancer(2021)
Authors: Q Lecocq, Pieterjan Debie, Janik Puttemans, R M Awad, L De Beck, T Ertveldt, Y De Vlaeminck, Cleo Goyvaerts, G Raes, Marleen Keyaerts, et al.
- Decorating sdAbs with Chelators(2021)
Authors: Henri Baudhuin, Janik Puttemans, Heleen Hanssens, Philippe Vanwolleghem, Sophie Hernot, G Raes, Catarina Xavier, Tony Lahoutte, Pieterjan Debie
- The Design and Preclinical Evaluation of a Single-Label Bimodal Nanobody Tracer for Image-Guided Surgery(2021)
Authors: Pieterjan Debie, Noemi Declerck, Danny M van Willigen, Celine M Huygen, Bieke De Sloovere, Lukasz Mateusiak, Jessica Bridoux, Janik Puttemans, Nick Devoogdt, Fijs W B van Leeuwen, et al.
Pages: 1-14 - CS1-specific single-domain antibodies labeled with Actinium-225 prolong survival and increase CD8+ T cells and PD-L1 expression in Multiple Myeloma(2021)
Authors: Kim De Veirman, Janik Puttemans, Ahmet Krasniqi, T Ertveldt, Heleen Hanssens, Ema Romão, Dirk Hose, Cleo Goyvaerts, Philip Vlummens, Serge Muyldermans, et al.