Researcher
Jan SPAAS
- Keywords (Ghent University):Carnosine, Neuroinflammation, Multiple Sclerosis, Histidine-containing dipeptides
- Keywords (Hasselt University):Physical education and physiotherapy, Biomedical sciences (incl. biochemistry)
- Disciplines (Ghent University):Neurological and neuromuscular diseases, Neurophysiology, Autoimmunity
- Disciplines (Hasselt University):Autoimmunity, Neurological and neuromuscular diseases, Neurophysiology
- See also: Jan Spaas (Ghent University)
Affiliations
- Department of Movement and Sports Sciences (Department)
Member
From23 Oct 2020 → 24 Sep 2023 - Cardio & organ systems (Department)
Member
From1 Jan 2020 → 30 Sep 2023 - Cardio & organ systems (Research group)
Member
From1 Jan 2020 → 30 Sep 2023 - Faculty of Medicine and Life Sciences (Faculty)
Member
From1 Oct 2018 → 30 Sep 2023 - Physiology - Biochemistry - Immunology (Department)
Member
From1 Oct 2018 → 31 Dec 2019 - Physiology (Research group)
Member
From1 Oct 2018 → 31 Dec 2019 - Rehabilitation Sciences (Faculty)
Member
From1 Sep 2018 → 30 Sep 2018 - Biomedical Research Institute (Research institute)
Member
From1 Oct 2017 → 30 Sep 2023 - Rehabilitation Sciences & Physiotherapy (Department)
Member
From1 Oct 2017 → 30 Sep 2018 - Rehabilitation Research Center (Research group)
Member
From1 Oct 2017 → 30 Sep 2018 - Faculty of Medicine and Life Sciences (Faculty)
Member
From1 Oct 2017 → 31 Aug 2018
Projects
1 - 3 of 3
- Carnosine in neuroinflammation and demyelination: a versatile dipeptide to halt damage and boost repair in Multiple Sclerosis?From1 Nov 2021 → 30 Sep 2023Funding: FWO fellowships
- Carnosine in neuroinflammation and demyelination: a versatile dipeptide to halt damage and boost repair in Multiple Sclerosis?From1 Nov 2019 → 31 Oct 2021Funding: FWO fellowships
- Impact of muscle carnosine loading on exercise capacity and muscle contractile characteristics in Experimental Autoimmune Encephalomyelitis (EAE) and Multiple Sclerosis.From1 Oct 2017 → 30 Oct 2019Funding: BOF - Doctoral projects
Publications
1 - 10 of 17
- Carnosine on the move: histidine-containing dipeptides in the pathophysiology and treatment of multiple sclerosis(2023)
Authors: Jan SPAAS, Bert OP 'T EIJNDE
- Extensive profiling of histidine-containing dipeptides reveals species- and tissue-specific distribution and metabolism in mice, rats, and humans(2023)
Authors: Thibaux Van der Stede, Jan SPAAS, Sarah de Jager, Jana DE BRANDT, Camilla Hansen, Jan Stautemas, Bjarne Vercammen, Siegrid De Baere, Siska Croubels, Charles-Henri Van Assche, et al.
- Carnosine synthase deficiency aggravates neuroinflammation in multiple sclerosis(2023)
Authors: Jan SPAAS, Thibaux Van der Stede, Sarah de Jager, Annet VAN DE WATERWEG BERENDS, Assia TIANE, Hans Baelde, Shahid P. Baba, Matthias Eckhardt, Esther WOLFS, Tim VANMIERLO, et al.
- Effect of beta-alanine supplementation on histidine-containing dipeptides in persons with COPD(2023)
Authors: Jana DE BRANDT, Thibaux Van der Stede, Jan SPAAS, Sarah De Jager, Chris BURTIN, Martijn A. SPRUIT, Wim Derave
- Changes in sedentary behaviour and physical activity in response to an exercise intervention in persons with multiple sclerosis(2022)
Authors: Ine NIESTE, Jan SPAAS, Paul VAN ASCH, Bert OP 'T EIJNDE
Pages: 685 - 686 - Altered muscle oxidative phenotype impairs exercise tolerance but does not Improve after exercise training in multiple sclerosis(2022)
Authors: Jan SPAAS, Richie P. Goulding, Charly KEYTSMAN, Lena FONTEYN, Jack VAN HORSSEN, Richard T. Jaspers, Bert OP 'T EIJNDE, Rob C. I. Wust
Pages: 2537 - 2550 - Lifestyle interventions to reduce sedentary behaviour in clinical populations: A systematic review and meta-analysis of different strategies and effects on cardiometabolic health(2021)
Authors: Ine NIESTE, Wouter FRANSSEN, Jan SPAAS, Liesbeth BRUCKERS, H.H.C.M. SAVELBERG, Bert OP 'T EIJNDE
- Oxidative stress and impaired oligodendrocyte precursor cell differentiation in neurological disorders(2021)
Authors: Jan SPAAS, Lieve VAN VEGGEL, Melissa SCHEPERS, Assia TIANE, Jack VAN HORSSEN, David WILSON, Pablo R. Moya, Elisabeth PICCART, Niels HELLINGS, Bert OP 'T EIJNDE, et al.
Pages: 4615 - 4637 - Carnosine quenches the reactive carbonyl acrolein in the central nervous system and attenuates autoimmune neuroinflammation(2021)
Authors: Jan SPAAS, Wouter FRANSSEN, Charly KEYTSMAN, Laura Blancquaert, Tim VANMIERLO, Jeroen BOGIE, Bieke BROUX, Niels HELLINGS, Jack VAN HORSSEN, Dheeraj Kumar Posa, et al.
- Can consumer wearable activity tracker-based interventions improve physical activity and cardiometabolic health in patients with chronic diseases? A systematic review and meta-analysis of randomised controlled trials(2020)
Authors: Wouter FRANSSEN, Gregor H. L. M. Franssen, Jan SPAAS, Francesca SOLMI, Bert OP 'T EIJNDE