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Researcher
Jan Pascal Kahler
- Disciplines:Organic chemistry, Biochemistry and metabolism, Systems biology, Medical biochemistry and metabolism
Affiliations
- Laboratory of Chemical Biology (Division)
Member
From15 Mar 2017 → Today
Projects
1 - 1 of 1
- Synthesis of novel fluorescently quenched activity-based probes for serine proteases and the application in live cell imaging using various detection techniquesFrom7 Mar 2017 → 31 Mar 2022Funding: FWO Strategic Basic Research Grant
Publications
1 - 7 of 7
- Synthesis of Novel Fluorescent Phosphonate and Phosphinate Activity-based Probes and their Application for the Detection of Serine Proteases(2022)
Authors: Jan Pascal Kahler, Steven Verhelst
- Phosphinate esters as novel warheads for activity-based probes targeting serine proteases(2021)
Authors: Jan Pascal Kahler, Steven Verhelst
Pages: 1285 - 1290 - Facile Synthesis of Aminomethyl Phosphinate Esters as Serine Protease Inhibitors with Primed Site Interaction(2020)
Authors: Jan Pascal Kahler, Stijn Lenders, Merel van de Plassche, Steven Verhelst
Pages: 1739 - 1744 - Activity-Based Protein Profiling of Serine Proteases in Immune Cells(2020)
Authors: Jan Pascal Kahler, Roeland Vanhoutte, Steven Verhelst
- ATP13A2 deficiency disrupts lysosomal polyamine export(2020)
Authors: Sarah van Veen, Shaun Martin, Chris Van den Haute, Veronick Benoy, Roeland Vanhoutte, Jan Pascal Kahler, Jean-Paul Decuypere, Géraldine Gelders, Johan Swinnen, Wim Annaert, et al.
Pages: 419 - 424 - Recent Advances in Activity-Based Protein Profiling of Proteases(2019)
Authors: Suravi Chakrabarty, Jan Pascal Kahler, Merel van de Plassche, Roeland Vanhoutte, Steven Verhelst
Pages: 253 - 281 - Clickable polyamine derivatives as chemical probes for the polyamine transport system(2018)
Authors: Roeland Vanhoutte, Jan Pascal Kahler, Shaun Martin, Sarah van Veen, Steven Verhelst
Pages: 907 - 911
Patents
1 - 1 of 1