Researcher
Jan Michiels
- Disciplines (Flanders Institute for Biotechnology):Auto-ecology, Biogeography and phylogeography, Anthropological genetics, Bacteriology, Biogeochemical cycli, Epigenomics
- Disciplines (KU Leuven):Biological system engineering
- See also: Jan Michiels (Flanders Institute for Biotechnology)
Affiliations
- Microbial and Plant Genetics (CMPG) (Division)
Responsible
From1 Aug 2020 → Today - Microbial and Plant Genetics (CMPG) (Division)
Member
From1 Aug 2020 → Today - Michiels Lab (Research group)
Responsible
From1 Oct 2017 → Today - Centre of Microbial and Plant Genetics (Division)
Member
From1 Aug 2005 → 31 Jul 2020
Projects
1 - 10 of 63
- Protein Aggregates: A Window into Bacterial Antibiotic Tolerance and DormancyFrom1 Jan 2024 → TodayFunding: FWO research project (including WEAVE projects)
- Unraveling the essential role of the universally conserved GTPase Obg in bacteriaFrom1 Oct 2023 → 2 Oct 2023Funding: Own budget, for example: patrimony, inscription fees, gifts
- Mutational robustness and evolvability in model microbesFrom1 Oct 2023 → TodayFunding: Fund Recuperation Fiscal Exemption
- An automated multi-mode reader for high-throughput, highly sensitive and time-resolved measurements of fluorescence, luminescence and absorbance of microbial culturesFrom1 Jan 2023 → TodayFunding: BOF - scientific equipment program
- Evolutionary trajectories of antibiotic susceptibility in longitudinal bacterial isolatesFrom3 Oct 2022 → TodayFunding: FWO fellowships
- Deciphering persister awakening in uropathogenic Escherichia coli through CRISPRi screeningFrom29 Sep 2022 → TodayFunding: FWO fellowships
- Combined computing and experimental platform for microbial strain optimization towards biochemicals productionFrom5 Sep 2022 → TodayFunding: FWO fellowships
- The role of bacterial persistence in the evolvability of antibiotic resistanceFrom1 Mar 2022 → TodayFunding: FWO fellowships
- MyCOS-Synthetic biology for a sustainable conversion of mycelia waste streams into valuable biobased chitooligosaccharides for plant health.From1 Jan 2022 → 31 Dec 2023Funding: FWO Thematic call for research projects in the field of bioeconomy
- Digging deep into the arsenal of calcium-dependent antibiotics through highly targeted genotype-based selectionFrom1 Jan 2022 → TodayFunding: FWO research project (including WEAVE projects)
Publications
41 - 50 of 182
- Enrichment of persisters enabled by a ß-lactam-induced filamentation method reveals their stochastic single-cell awakening(2019)
Authors: Etthel Windels, Kevin Verstrepen, Bram Van den Bergh, Jan Michiels
- Mechanistic insights in HokB-mediated persister formation and awakening(2019)
Authors: Dorien Wilmaerts, Jan Michiels, Natalie Verstraeten
- Biochemical determinants of ObgE-mediated persistence(2019)
Authors: Natalie Verstraeten, Bram Van den Bergh, Pauline Herpels, Elen Louwagie, Dorien Wilmaerts, Liselot Dewachter, Maarten Fauvart, Jan Michiels
Pages: 1593 - 1608 - A droplet microfluidics platform for scalable and high-throughput isolation of antibiotic-producing microbes(2019)
Authors: Pieter Berden, Liesbet Lagae, Jan Michiels, Maarten Fauvart
Pages: 833 - 834 - Bacterial Heterogeneity and Antibiotic Survival: Understanding and Combatting Persistence and Heteroresistance(2019)
Authors: Liselot Dewachter, Maarten Fauvart, Jan Michiels
Pages: 255 - 267 - Antibiotics: Combatting Tolerance To Stop Resistance(2019)
Authors: Etthel Windels, Bram Van den Bergh, Maarten Fauvart, Jan Michiels
- HokB monomerization and membrane repolarization control persister awakening(2019)
Authors: Dorien Wilmaerts, Liselot Dewachter, Celien Bollen, Natalie Verstraeten, Jan Michiels
Pages: 1031 - 1042 - Study of β-lactam induced bacteriolysis using high-throughput time-resolved microscopy and mechanical bacteriolysis by nanostructured surfaces(2019)
Authors: taiyeb Zahir, Jan Michiels, Maarten Fauvart
- High-throughput time-resolved morphology screening in bacteria reveals phenotypic responses to antibiotics.(2019)
Authors: Taiyeb Zahir, Rafael Camacho, Raffaele Vitale, Cyril Ruckebusch, Johan Hofkens, Maarten Fauvart, Jan Michiels
Pages: 269 - High-throughput time-resolved morphology screening in bacteria reveals phenotypic responses to antibiotics(2019)
Authors: Raffaele Vitale, Johan Hofkens, Jan Michiels