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Researcher
Jan Michiels
- Disciplines (Flanders Institute for Biotechnology):Auto-ecology, Biogeography and phylogeography, Anthropological genetics, Bacteriology, Biogeochemical cycli, Epigenomics
- Disciplines (KU Leuven):Biological system engineering
- See also: Jan Michiels (Flanders Institute for Biotechnology)
Affiliations
- Microbial and Plant Genetics (CMPG) (Division)
Responsible
From1 Aug 2020 → Today - Microbial and Plant Genetics (CMPG) (Division)
Member
From1 Aug 2020 → Today - Michiels Lab (Research group)
Responsible
From1 Oct 2017 → Today - Centre of Microbial and Plant Genetics (Division)
Member
From1 Aug 2005 → 31 Jul 2020
Projects
1 - 10 of 62
- Protein Aggregates: A Window into Bacterial Antibiotic Tolerance and DormancyFrom1 Jan 2024 → TodayFunding: FWO research project (including WEAVE projects)
- Unraveling the essential role of the universally conserved GTPase Obg in bacteriaFrom1 Oct 2023 → 2 Oct 2023Funding: Own budget, for example: patrimony, inscription fees, gifts
- An automated multi-mode reader for high-throughput, highly sensitive and time-resolved measurements of fluorescence, luminescence and absorbance of microbial culturesFrom1 Jan 2023 → TodayFunding: BOF - scientific equipment program
- Evolutionary trajectories of antibiotic susceptibility in longitudinal bacterial isolatesFrom3 Oct 2022 → TodayFunding: FWO fellowships
- Deciphering persister awakening in uropathogenic Escherichia coli through CRISPRi screeningFrom29 Sep 2022 → TodayFunding: FWO fellowships
- Combined computing and experimental platform for microbial strain optimization towards biochemicals productionFrom5 Sep 2022 → TodayFunding: FWO fellowships
- The role of bacterial persistence in the evolvability of antibiotic resistanceFrom1 Mar 2022 → TodayFunding: FWO fellowships
- MyCOS-Synthetic biology for a sustainable conversion of mycelia waste streams into valuable biobased chitooligosaccharides for plant health.From1 Jan 2022 → 31 Dec 2023Funding: FWO Thematic call for research projects in the field of bioeconomy
- Digging deep into the arsenal of calcium-dependent antibiotics through highly targeted genotype-based selectionFrom1 Jan 2022 → TodayFunding: FWO research project (including WEAVE projects)
- deCiphering bacterial peRsIsTence of Individual Cells down to Atomic LevelFrom1 Jan 2022 → TodayFunding: FWO EOS
Publications
11 - 20 of 183
- Deep mutational scanning of essential bacterial proteins can guide antibiotic development(2023)
Authors: Liselot Dewachter, Thomas Schalck, Jan Michiels
- Bacterial host factors involved in conjugation(2022)
Authors: Laetitia Van Wonterghem, Jan Michiels, Natalie Verstraeten
- Amplification Efficiency and Template Accessibility as Distinct Causes of Rain in Digital PCR: Monte Carlo Modeling and Experimental Validation(2022)
Authors: Pieter Berden, Liesbet Lagae, Jan Michiels, Maarten Fauvart
Pages: 15781 - 15789 - Model-based classification of rain in digital PCR as a benchmark for assay reliability(2022)
Authors: Pieter Berden, Jan Michiels
Pages: 755 - 756Number of pages: 2 - Assessing persister awakening dynamics following antibiotic treatment in E. coli(2022)
Authors: Dorien Wilmaerts, Sander Govers, Jan Michiels
- Ecology and evolution of antibiotic persistence(2022)
Authors: Laure Verstraete, Bram Van den Bergh, Natalie Verstraeten, Jan Michiels
Pages: 1 - 14 - Genome-Wide Association Study Reveals Host Factors Affecting Conjugation in Escherichia coli(2022)
Authors: Laetitia Van Wonterghem, Natalie Verstraeten, Jan Michiels
- Transcription-coupled DNA repair underlies variation in persister awakening and the emergence of resistance(2022)
Authors: Dorien Wilmaerts, Paul Matthay, Jan Michiels
- Mutations in respiratory complex I promote antibiotic persistence through alterations in intracellular acidity and protein synthesis(2022)
Authors: Bram Van den Bergh, Liselot Dewachter, Maarten Fauvart, Jan Michiels
Pages: 1 - 18 - Studying bacterial persistence: Established methods and current advances(2021)
Authors: Elen Louwagie, Laure Verstraete, Jan Michiels, Natalie Verstraeten
Pages: 3 - 20